Acetyl-CoA carboxylase (ACC) 2 and 1 inhibitor (IC50values are 45 and 98 nM, respectively). Reduces hepatic and skeletal muscle malonyl-CoA levels in rats. Also inhibits hepaticde novolipogenesis and reduces whole body respiratory exchange ratio in rats.
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
Action Type
INHIBITOR
Mechanism of action
Acetyl-CoA carboxylase inhibitor
Product Description
Product Application:
PF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively.
Product Describtion:
PF-05175157 has been used as an acetyl-Coenzyme A carboxylase (ACC) inhibitor to study its effects on the infection of flavivirus.
D2312516