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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P648636-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $310.90 | |
P648636-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $480.90 | |
P648636-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $850.90 | |
P648636-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,350.90 |
Synonyms | CS-0028357 | BDBM50466964 | P-345 | Q27896272 | DB15124 | 1-(5-Chloro-6-(2-methylpropoxy)-3-pyridinyl)-3-methyl-N-(methylsulfonyl)-1H-indazole-5-carboxamide | 8RAL5N48VT | 1H-Indazole-5-carboxamide, 1-[5-chloro-6-(2-methylpropoxy)-3-pyridinyl]-3-methyl-n- |
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Specifications & Purity | ≥99% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | PF-05241328 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channels (Nav1.7) , with an IC 50 of 31 nM. Form:Solid IC50& Target:IC50: 31 nM (Nav1.7) |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 1-[5-chloro-6-(2-methylpropoxy)pyridin-3-yl]-3-methyl-N-methylsulfonylindazole-5-carboxamide |
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INCHI | InChI=1S/C19H21ClN4O4S/c1-11(2)10-28-19-16(20)8-14(9-21-19)24-17-6-5-13(7-15(17)12(3)22-24)18(25)23-29(4,26)27/h5-9,11H,10H2,1-4H3,(H,23,25) |
InChi Key | RVTSXVZXEGFIPW-UHFFFAOYSA-N |
Canonical SMILES | CC1=NN(C2=C1C=C(C=C2)C(=O)NS(=O)(=O)C)C3=CC(=C(N=C3)OCC(C)C)Cl |
Isomeric SMILES | CC1=NN(C2=C1C=C(C=C2)C(=O)NS(=O)(=O)C)C3=CC(=C(N=C3)OCC(C)C)Cl |
PubChem CID | 68109743 |
Molecular Weight | 436.91 |
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Solubility | DMSO : 100 mg/mL (228.88 mM; ultrasonic and warming and heat to 60°C) |
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