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PF-06454589 - 10mM in DMSO, high purity , CAS No.1527473-30-8(DMSO)

Item Number

P655602

Grouped product items
SKU	Size	Availability	Price	Qty
P655602-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$105.90

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Basic Description

Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	PF-06447475 is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC 50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2 , respectively. PF-06447475 can be used for parkinson's disease (PD) research.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	PF-06447475 is a highly potent, selective, brain penetrant LRRK2 kinase inhibitor with IC 50 values of 3 nM and 11 nM for WT LRRK and G2019S LRRK2 , respectively. PF-06447475 can be used for parkinson's disease (PD) research.

LRRK2 Tchem Leucine-rich repeat serine/threonine-protein kinase 2 (0 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Canonical SMILES	CN1C=C(C=N1)C2=CNC3=C2C(=NC=N3)N4CCOCC4
Molecular Weight	284.32

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