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PF-06840003 - 98%, high purity , CAS No.198474-05-4, Inhibitor of indoleamine 2;3-dioxygenase 1

Moligand™

≥98%

CAS#: 198474-05-4
Formula: C₁₂H₉FN₂O₂
Molecular Weight: 232.21
PubChem CID: 23063810

Item Number

P175464

Grouped product items
SKU	Size	Availability	Price
P175464-5mg	5mg	In stock	$75.90
P175464-10mg	10mg	In stock	$107.90
P175464-25mg	25mg	In stock	$173.90
P175464-50mg	50mg	In stock	$238.90
P175464-100mg	100mg	In stock	$380.90
P175464-250mg	250mg	In stock	$857.90

View related series

indoleamine 2，3-dioxygenase 1 Inhibitor Metabolic Enzyme/Protease

Basic Description

Synonyms	AKOS027252536 \| EOS200271 \| EOS-200271 \| Q420698 \| US9603836, Compound 1 \| GTPL9565 \| A925049 \| s8657 \| SCHEMBL5463464 \| EOS200271; EOS-200271; EOS 200271; PF 06840003; PF06840003 \| EX-A1186 \| NSC-796100 \| BP168137 \| DTXSID00630149 \| SB22834 \| AMY445 \| 2,
Specifications & Purity	Moligand™, ≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of indoleamine 2;3-dioxygenase 1

Associated Targets(Human)

IDO1 Tchem Indoleamine 2,3-dioxygenase 1 (10 Activities)

Discover Target: IDO1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

Discover Target: CYP2D6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

Discover Target: CYP1A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

Discover Target: CYP2C9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)

Discover Target: CYP2C19

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Homo sapiens (32628 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HeLa (62764 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

IDO1 Tchem Indoleamine 2,3-dioxygenase (6650 Activities)

Discover Target: IDO1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ABCG2 Tchem ATP-binding cassette sub-family G member 2 (4927 Activities)

Discover Target: ABCG2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Tdo2 Tryptophan 2,3-dioxygenase (8 Activities)

Discover Target: Tdo2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Canis familiaris (36305 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mus musculus (284745 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MC-38 (857 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

4T1 (1737 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

B16-F10 (4610 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CT26 (928 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Renca (39 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasma (328 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ido1 Indoleamine 2,3-dioxygenase 1 (313 Activities)

Discover Target: Ido1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Ido2 Indoleamine 2,3-dioxygenase 2 (105 Activities)

Discover Target: Ido2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MDCKII-LE (120 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione
INCHI	InChI=1S/C12H9FN2O2/c13-6-1-2-10-7(3-6)9(5-14-10)8-4-11(16)15-12(8)17/h1-3,5,8,14H,4H2,(H,15,16,17)
InChi Key	MXKLDYKORJEOPR-UHFFFAOYSA-N
Canonical SMILES	C1C(C(=O)NC1=O)C2=CNC3=C2C=C(C=C3)F
Isomeric SMILES	C1C(C(=O)NC1=O)C2=CNC3=C2C=C(C=C3)F
Alternate CAS	198474-05-4
PubChem CID	23063810
MeSH Entry Terms	3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione;EOS200271;PF-06840003
Molecular Weight	232.21

Certificates

Certificate of Analysis(COA)

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6 results found

Lot Number	Certificate Type	Date	Item
B2225230	Certificate of Analysis	Dec 10, 2024	P175464
B2225237	Certificate of Analysis	Dec 10, 2024	P175464
B2225240	Certificate of Analysis	Dec 10, 2024	P175464
B2225245	Certificate of Analysis	Dec 10, 2024	P175464
B2225246	Certificate of Analysis	Dec 10, 2024	P175464
B2225254	Certificate of Analysis	Dec 10, 2024	P175464

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

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PF-06840003 - 98%, high purity , CAS No.198474-05-4, Inhibitor of indoleamine 2;3-dioxygenase 1

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Safety and Hazards(GHS)

Related Documents

Solution Calculators

Molarity Calculator

Dilution Calculator

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