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PF-06869206 - 98%, high purity , CAS No.2227425-05-8

  • ≥98%
Item Number
P412139
Grouped product items
SKUSizeAvailabilityPrice Qty
P412139-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$52.90
P412139-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$92.90
P412139-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$202.90
P412139-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$356.90
View related series
Sodium Channel

Basic Description

Specifications & Purity≥98%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Information

PF-06869206 is an orally selective bioavailable inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1) with IC50 of 380 nM.

Associated Targets

SLC20A2 Tbio Sodium-dependent phosphate transporter 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC20A1 Tbio Sodium-dependent phosphate transporter 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC34A3 Tbio Sodium-dependent phosphate transport protein 2C 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC34A2 Tchem Sodium-dependent phosphate transport protein 2B 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLC34A1 Tchem Sodium-dependent phosphate transport protein 2A 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 3-chloro-7-[(2S)-2-(hydroxymethyl)morpholin-4-yl]-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
INCHI InChI=1S/C15H14ClF3N4O2/c1-7-10(16)11-12(21-7)13(23-2-3-25-8(5-23)6-24)9(4-20)14(22-11)15(17,18)19/h8,21,24H,2-3,5-6H2,1H3/t8-/m0/s1
InChi Key ATFQBBCQZKVZJN-QMMMGPOBSA-N
Canonical SMILES CC1=C(C2=C(N1)C(=C(C(=N2)C(F)(F)F)C#N)N3CCOC(C3)CO)Cl
Isomeric SMILES CC1=C(C2=C(N1)C(=C(C(=N2)C(F)(F)F)C#N)N3CCO[C@@H](C3)CO)Cl
PubChem CID 134159047
Molecular Weight 374.74

Certificates

Certificate of Analysis(COA)

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8 results found

Lot NumberCertificate TypeDateItem
B2419537Certificate of AnalysisJan 08, 2024 P412139
B2419538Certificate of AnalysisJan 08, 2024 P412139
B2419539Certificate of AnalysisJan 08, 2024 P412139
B2419543Certificate of AnalysisJan 08, 2024 P412139
B2419544Certificate of AnalysisJan 08, 2024 P412139
B2419545Certificate of AnalysisJan 08, 2024 P412139
B2419546Certificate of AnalysisJan 08, 2024 P412139
B2419548Certificate of AnalysisJan 08, 2024 P412139

Safety and Hazards(GHS)

Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P301+P312:IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell.

Related Documents

Solution Calculators