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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P412139-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $52.90 | |
P412139-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $92.90 | |
P412139-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $202.90 | |
P412139-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $356.90 |
Specifications & Purity | ≥98% |
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Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | Information PF-06869206 is an orally selective bioavailable inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1) with IC50 of 380 nM. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 3-chloro-7-[(2S)-2-(hydroxymethyl)morpholin-4-yl]-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile |
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INCHI | InChI=1S/C15H14ClF3N4O2/c1-7-10(16)11-12(21-7)13(23-2-3-25-8(5-23)6-24)9(4-20)14(22-11)15(17,18)19/h8,21,24H,2-3,5-6H2,1H3/t8-/m0/s1 |
InChi Key | ATFQBBCQZKVZJN-QMMMGPOBSA-N |
Canonical SMILES | CC1=C(C2=C(N1)C(=C(C(=N2)C(F)(F)F)C#N)N3CCOC(C3)CO)Cl |
Isomeric SMILES | CC1=C(C2=C(N1)C(=C(C(=N2)C(F)(F)F)C#N)N3CCO[C@@H](C3)CO)Cl |
PubChem CID | 134159047 |
Molecular Weight | 374.74 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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B2419537 | Certificate of Analysis | Jan 08, 2024 | P412139 |
B2419538 | Certificate of Analysis | Jan 08, 2024 | P412139 |
B2419539 | Certificate of Analysis | Jan 08, 2024 | P412139 |
B2419543 | Certificate of Analysis | Jan 08, 2024 | P412139 |
B2419544 | Certificate of Analysis | Jan 08, 2024 | P412139 |
B2419545 | Certificate of Analysis | Jan 08, 2024 | P412139 |
B2419546 | Certificate of Analysis | Jan 08, 2024 | P412139 |
B2419548 | Certificate of Analysis | Jan 08, 2024 | P412139 |
Signal | Warning |
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Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P301+P312:IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell. |