PF-07062119, Antibody of CD3e;Antibody of Guanylyl cyclase-C

Features and benefits
    Item Number
    Ab175630
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    Ab175630-1mg
    1mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $2,668.90
    Ab175630-5mg
    5mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $4,668.90

    Basic Description

    Product NamePF-07062119
    Specifications & PurityMoligand™
    GradeMoligand™
    Action TypeANTIBODY
    Mechanism of actionAntibody of CD3e;Antibody of Guanylyl cyclase-C

    Product Properties

    CASAb175630

    Associated Targets(Human)

    CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
    GUCY2C Tclin Heat-stable enterotoxin receptor (0 Activities)
    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
    CD3E Tclin T-cell surface glycoprotein CD3 epsilon chain (0 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    GUCY2C Tclin Heat-stable enterotoxin receptor (5 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

    Mechanisms of Action

    Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

    Certificates

    Certificate of Analysis(COA)

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    Related Documents

    References

    1. Mathur D, Root AR, Bugaj-Gaweda B, Bisulco S, Tan X, Fang W, Kearney JC, Lucas J, Guffroy M, Golas J et al..  (2020)  A Novel GUCY2C-CD3 T-Cell Engaging Bispecific Construct (PF-07062119) for the Treatment of Gastrointestinal Cancers..  Clin Cancer Res,  26  (9): (2188-2202).  [PMID:31996389] [10.1021/op500134e]

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