PF-622 , CAS No.898235-65-9

Item Number

P330789

Grouped product items
SKU	Size	Availability	Price	Qty
P330789-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$42.90
P330789-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$76.90

a novel, potent and selective inhibitor of FAAH (fatty acid amide hydrolase)

Basic Description

Synonyms	PF-622 \| NCGC00388308-02 \| FAAH Inhibitor, PF-622 \| N-phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carboxamide \| DTXSID00467917 \| SCHEMBL3600412 \| BDBM26741
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	PF-622 is a potent, irreversible, time-dependent FAAH inhibitor by covalently modifying the enzyme's active site serine (IC\|50\|= 33nM). It is completely selective for FAAH relative to other mammalian serine hydrolases.

Associated Targets(Human)

FAAH Tchem Fatty-acid amide hydrolase 1 (6 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TRPV1 Tclin Vanilloid receptor (8273 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	N-phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carboxamide
INCHI	InChI=1S/C21H22N4O/c26-21(23-18-7-2-1-3-8-18)25-14-12-24(13-15-25)16-19-11-10-17-6-4-5-9-20(17)22-19/h1-11H,12-16H2,(H,23,26)
InChi Key	SNTCRRMCALVGNL-UHFFFAOYSA-N
Canonical SMILES	C1CN(CCN1CC2=NC3=CC=CC=C3C=C2)C(=O)NC4=CC=CC=C4
Isomeric SMILES	C1CN(CCN1CC2=NC3=CC=CC=C3C=C2)C(=O)NC4=CC=CC=C4
PubChem CID	11515763
Molecular Weight	346.44

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Basic Description