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PHA-767491 - ≥98%, high purity , CAS No.845714-00-3, Inhibitor of MAPK activated protein kinase 2;Inhibitor of ribosomal protein S6 kinase A4

Specifications & Purity: ≥98%

CAS#: 845714-00-3
Formula: C₁₂H₁₁N₃O
Molecular Weight: 213.24
PubChem CID: 11715767

Item Number

P127009

Grouped product items
SKU	Size	Availability	Price
P127009-5mg	5mg	In stock	$209.90
P127009-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$940.90
P127009-100mg	100mg	In stock	$3,385.90

Potent dual Cdc7 and Cdk9 kinase inhibitor

View related series

MAPK activated protein kinase 2 Inhibitor ribosomal protein S6 kinase A4 Inhibitor

Basic Description

Synonyms	PHA-767491\|845714-00-3\|PHA 767491\|2-pyridin-4-yl-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one\|CAY10572\|1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one\|CAY10572(PHA-767491)\|5M2GUN688C\|2-(pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Dry ice
Action Type	INHIBITOR
Mechanism of action	Inhibitor of MAPK activated protein kinase 2;Inhibitor of ribosomal protein S6 kinase A4

Associated Targets

DYRK1B Tchem Dual specificity tyrosine-phosphorylation-regulated kinase 1B 0 Activities

Discover Target: DYRK1B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

DYRK1A Tchem Dual specificity tyrosine-phosphorylation-regulated kinase 1A 0 Activities

Discover Target: DYRK1A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CDK9 Tchem Cyclin-dependent kinase 9 0 Activities

Discover Target: CDK9

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CDK8 Tchem Cyclin-dependent kinase 8 0 Activities

Discover Target: CDK8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CDC7 Tchem Cell division cycle 7-related protein kinase 0 Activities

Discover Target: CDC7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PKN2 Tchem Serine/threonine-protein kinase N2 0 Activities

Discover Target: PKN2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PRKG1 Tchem cGMP-dependent protein kinase 1 0 Activities

Discover Target: PRKG1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAPKAPK2 Tchem MAP kinase-activated protein kinase 2 1 Activities

Discover Target: MAPKAPK2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CLK4 Tchem Dual specificity protein kinase CLK4 0 Activities

Discover Target: CLK4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RPS6KA4 Tchem Ribosomal protein S6 kinase alpha-4 1 Activities

Discover Target: RPS6KA4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	2-pyridin-4-yl-1,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one
INCHI	InChI=1S/C12H11N3O/c16-12-9-7-11(8-1-4-13-5-2-8)15-10(9)3-6-14-12/h1-2,4-5,7,15H,3,6H2,(H,14,16)
InChi Key	DKXHSOUZPMHNIZ-UHFFFAOYSA-N
Canonical SMILES	C1CNC(=O)C2=C1NC(=C2)C3=CC=NC=C3
Isomeric SMILES	C1CNC(=O)C2=C1NC(=C2)C3=CC=NC=C3
Alternate CAS	845714-00-3
PubChem CID	11715767
MeSH Entry Terms	PHA 767491;PHA-767491;PHA767491
Molecular Weight	213.24

Certificates

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3 results found

Lot Number	Certificate Type	Date	Item
J2116165	Certificate of Analysis	Aug 16, 2023	P127009
J2116167	Certificate of Analysis	Aug 16, 2023	P127009
J2116168	Certificate of Analysis	Aug 16, 2023	P127009

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