Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P106382-1g | 1g | In stock | $9.90 | |
P106382-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $24.90 | |
P106382-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $69.90 | |
P106382-100g | 100g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $249.90 | |
P106382-250g | 250g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $561.90 |
Synonyms | AS-14257 | Phenanthroquinone | SR-01000512656 | SB67051 | BP-13416 | SCHEMBL43050 | SR-01000512656-1 | Phenanthrene,10-dihydro-9,10-dioxo- | HMS2231F24 | CS-W015223 | 1,2-Dione-Based Compound, 14 | 9,10-Phenanthraquinone | Phenanthraquinone | P1136 | 9,10 |
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Specifications & Purity | ≥99% |
Storage Temp | Room temperature |
Shipped In | Normal |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | phenanthrene-9,10-dione |
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INCHI | InChI=1S/C14H8O2/c15-13-11-7-3-1-5-9(11)10-6-2-4-8-12(10)14(13)16/h1-8H |
InChi Key | YYVYAPXYZVYDHN-UHFFFAOYSA-N |
Canonical SMILES | C1=CC=C2C(=C1)C3=CC=CC=C3C(=O)C2=O |
Isomeric SMILES | C1=CC=C2C(=C1)C3=CC=CC=C3C(=O)C2=O |
WGK Germany | 3 |
RTECS | SF7875000 |
PubChem CID | 6763 |
Molecular Weight | 208.21 |
Beilstein | 608838 |
Reaxy-Rn | 608838 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
H2415494 | Certificate of Analysis | Aug 08, 2024 | P106382 |
H2415495 | Certificate of Analysis | Aug 08, 2024 | P106382 |
H2415502 | Certificate of Analysis | Aug 08, 2024 | P106382 |
H2415503 | Certificate of Analysis | Aug 08, 2024 | P106382 |
H2415504 | Certificate of Analysis | Aug 08, 2024 | P106382 |
H2415505 | Certificate of Analysis | Aug 08, 2024 | P106382 |
I2007262 | Certificate of Analysis | Jun 17, 2024 | P106382 |
H1823045 | Certificate of Analysis | Jun 21, 2022 | P106382 |
I2205491 | Certificate of Analysis | Nov 16, 2021 | P106382 |
E2312269 | Certificate of Analysis | May 19, 2021 | P106382 |
E2411038 | Certificate of Analysis | Apr 28, 2021 | P106382 |
K2207081 | Certificate of Analysis | Apr 28, 2021 | P106382 |
K2207085 | Certificate of Analysis | Apr 28, 2021 | P106382 |
Flash Point(°F) | 245 °C |
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Flash Point(°C) | 245 °C |
Boil Point(°C) | 360°C |
Melt Point(°C) | 209-212 °C(lit.) |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | SF7875000 |
Reaxy-Rn | 608838 |
Merck Index | 7213 |
1. Qiushuang Li, Bing Zhao, Xiangdong Kong, Liyan Wang, Wei Kan, Bo Song, Rui Yu, Pengfei Zhang. (2024) Multi-responsive fluorescent covalent organic framework based on phenanthro[9,10-d]imidazole moiety for relayed detection of Cu2+/Al3+ followed by PO43− and its applications. DYES AND PIGMENTS, 222 (111886). [PMID:] [10.1016/j.dyepig.2023.111886] |
2. Junqi Liu, Meng Wang, Saijin Wang, Yanli Zhao, Shi Zhou, Jinlian Li, Dongmei Wu. (2024) Assessment of oxygenated polycyclic aromatic hydrocarbon cytotoxicity using TiO2-MXene/MWCNTs/PDA/GCE electrochemical sensor. ELECTROCHIMICA ACTA, 474 (8): (143515). [PMID:9873016] [10.1016/j.electacta.2023.143515] |
3. Minghui Liu, Shibo Sun, Yao Meng, Ling Wang, Haowen Liu, Wuyang Shi, Qiuyu Zhang, Weiping Xu, Bingbing Sun, Jianqiang Xu. (2023) Benzophenanthridine Alkaloid Chelerythrine Elicits Necroptosis of Gastric Cancer Cells via Selective Conjugation at the Redox Hyperreactive C-Terminal Sec498 Residue of Cytosolic Selenoprotein Thioredoxin Reductase. MOLECULES, 28 (19): (6842). [PMID:37836684] [10.3390/molecules28196842] |
4. Wang Xue, Ji Ting, Zhao Jie, Ding Zhao. (2023) 9,10-phenanthrenequinone anchored on nitrogen-doped carbon nanotubes for symmetrical supercapacitors with enhanced performance. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS, 34 (12): (1-16). [PMID:] [10.1007/s10854-023-10439-1] |
5. Yitao Lv, Yi Zhang, Yunyin Yang, Jingyan Li, Jiacheng Wang, Xilin Xiao, Min Zhang. (2023) Strategy of In Situ Electrochemical Regulation for Highly Enhanced Nonenzymatic Sensing of Carbaryl. ANALYTICAL CHEMISTRY, 95 (8): (4015–4023). [PMID:36802553] [10.1021/acs.analchem.2c04373] |
6. Di Li, Chuan Wang, Jiahui Hu, Wu Tang, Shan Jia, Meichen Guo, Cong Fan. (2022) Phenanthraquinone-based polymer organic cathodes for highly efficient Na-ion batteries. CHEMICAL ENGINEERING JOURNAL, 449 (137745). [PMID:] [10.1016/j.cej.2022.137745] |
7. Jian Wang, Suhua Luo. (2022) Volume holographic storage using sync-angular multiplexing by rotating material in thick photopolymer. OPTICS AND LASER TECHNOLOGY, 153 (108295). [PMID:] [10.1016/j.optlastec.2022.108295] |
8. Wenjuan Li, Yan Wu, Conghu Li, Liangliang Zhu. (2021) Effect of (E,E)-2,4-decadienal on Side-Chain Modification, Conformation Change, and Aggregation of Bovine Serum Albumin. EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 124 (1): (2100066). [PMID:] [10.1002/ejlt.202100066] |
9. Wenquan Huang, Yuehua Deng, Liping Ye, Qiuling Xie, Yanbin Jiang. (2021) Enhancing hemocompatibility and the performance of Au@silica nanoparticles by coating with cRGD functionalized zein. Materials Science & Engineering C-Materials for Biological Applications, 125 (112064). [PMID:33965097] [10.1016/j.msec.2021.112064] |
10. Yangyang Liu, Tao Wang, Xiaozhong Fang, Yue Deng, Hanyun Cheng, Aziz-Ur-Rahim Bacha, Iqra Nabi, Liwu Zhang. (2020) Brown carbon: An underlying driving force for rapid atmospheric sulfate formation and haze event. SCIENCE OF THE TOTAL ENVIRONMENT, 734 (139415). [PMID:32464390] [10.1016/j.scitotenv.2020.139415] |
11. Shuai Ji, Xian Shao, Zhen-yu Su, Lei Ji, Yu-jie Wang, Yun-su Ma, Lu Zhao, Yan Du, Meng-zhe Guo, Dao-quan Tang. (2019) Segmented scan modes and polarity-based LC-MS for pharmacokinetic interaction study between Fufang Danshen Dripping Pill and Clopidogrel Bisulfate Tablet. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 174 (367). [PMID:31202879] [10.1016/j.jpba.2019.05.055] |
12. Yaqin Gao, Yan Lyu, Xiang Li. (2019) Size distribution of airborne particle-bound PAHs and o-PAHs and their implications for dry deposition. Environmental Science-Processes & Impacts, 21 (7): (1184-1192). [PMID:31188374] [10.1039/C9EM00174C] |
13. Wenjuan Li, Haiyan Gao, Honglei Mu, Hangjun Chen, Xiangjun Fang, Yongjun Zhou, Fei Tao. (2015) Three different active aldehydes induce the production of advanced lipoxidation end products upon incubation with bovine serum albumin. EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 117 (9): (1432-1443). [PMID:] [10.1002/ejlt.201400339] |
14. Gong Hao, He Zihao, Peng Anlin, Zhang Xin, Cheng Biao, Sun Yue, Zheng Ling, Huang Kun. (2014) Effects of several quinones on insulin aggregation. Scientific Reports, 4 (1): (1-8). [PMID:25008537] [10.1038/srep05648] |
1. Janice L Hyatt,Randy M Wadkins,Lyudmila Tsurkan,Latorya D Hicks,M Jason Hatfield,Carol C Edwards,Charles R Ross,Stephanie A Cantalupo,Guy Crundwell,Mary K Danks,R Kip Guy,Philip M Potter. (2007-10-19) Planarity and constraint of the carbonyl groups in 1,2-diones are determinants for selective inhibition of human carboxylesterase 1.. Journal of medicinal chemistry, 50 ((23)): (5727-5734). [PMID:17941623] |
2. Michael C Byrns,Stephan Steckelbroeck,Trevor M Penning. (2007-10-24) An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent malignancies.. Biochemical pharmacology, 75 ((2)): (484-493). [PMID:17950253] |
3. Juan Manuel Russo,Raymond K Kostuk. (2007-10-24) Temperature dependence properties of holographic gratings in phenanthrenquinone doped poly(methyl methacrylate) photopolymers.. Applied optics, 46 ((30)): (7494-7499). [PMID:17952187] |
4. Chester E Rodriguez,Zhanna Sobol,Robert H Schiestl. (2007-10-26) 9,10-Phenanthrenequinone induces DNA deletions and forward mutations via oxidative mechanisms in the yeast Saccharomyces cerevisiae.. Toxicology in vitro : an international journal published in association with BIBRA, 22 ((2)): (296-300). [PMID:17959352] |
5. Pedro Sanchez-Cruz,Antonio E Alegría. (2009-03-24) Quinone-enhanced reduction of nitric oxide by xanthine/xanthine oxidase.. Chemical research in toxicology, 22 ((5)): (818-823). [PMID:19301825] |
6. Simone L Pival,Mario Klimacek,Bernd Nidetzky. (2009-04-17) The catalytic mechanism of NADH-dependent reduction of 9,10-phenanthrenequinone by Candida tenuis xylose reductase reveals plasticity in an aldo-keto reductase active site.. The Biochemical journal, 421 ((1)): (43-49). [PMID:19368528] |
7. M Soledade C Pedras,Yang Yu. (2009-04-18) Salt stress induces production of melanin related metabolites in the phytopathogenic fungus Leptosphaeria maculans.. Natural product communications, 4 ((1)): (53-58). [PMID:19370875] |
8. Toshiyuki Matsunaga,Marina Arakaki,Tetsuro Kamiya,Satoshi Endo,Ossama El-Kabbani,Akira Hara. (2009-05-16) Involvement of an aldo-keto reductase (AKR1C3) in redox cycling of 9,10-phenanthrenequinone leading to apoptosis in human endothelial cells.. Chemico-biological interactions, 181 ((1)): (52-60). [PMID:19442656] |
9. Petr Milko,Jana Roithová. (2009-11-26) Redox processes in the iron(III)/9,10-phenanthraquinone system.. Inorganic chemistry, 48 ((24)): (11734-11742). [PMID:19928842] |
10. Naoya Kishikawa,Hajime Nakashima,Kaname Ohyama,Kenichiro Nakashima,Naotaka Kuroda. (2010-05-06) Determination of 9, 10-phenanthrenequinone in airborne particulates by High-Performance Liquid Chromatography with post-column fluorescence derivatization using 2-aminothiophenol.. Talanta, 81 ((4-5)): (1852-1855). [PMID:20441985] |
11. Onkar S Bains,Thomas A Grigliatti,Ronald E Reid,K Wayne Riggs. (2010-09-15) Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.. The Journal of pharmacology and experimental therapeutics, 335 ((3)): (533-545). [PMID:20837989] |
12. Naoya Kishikawa. (2010-10-12) [Development of selective determination methods for quinones with fluorescence and chemiluminescence detection and their application to environmental and biological samples].. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 130 ((10)): (1319-1324). [PMID:20930484] |
13. Tony Hadibarata,Sanro Tachibana,Muhamad Askari. (2011-04-06) Identification of metabolites from phenanthrene oxidation by phenoloxidases and dioxygenases of Polyporus sp. S133.. Journal of microbiology and biotechnology, 21 ((3)): (299-304). [PMID:21464602] |
14. Toshiyuki Matsunaga,Yuhki Shinoda,Yukari Inoue,Yuki Shimizu,Mariko Haga,Satoshi Endo,Ossama El-Kabbani,Akira Hara. (2011-06-01) Aldo-keto reductase 1C15 as a quinone reductase in rat endothelial cell: its involvement in redox cycling of 9,10-phenanthrenequinone.. Free radical research, 45 ((7)): (848-857). [PMID:21623689] |
15. Naoya Kishikawa,Maiko Nakao,Mohamed Saleh Elgawish,Kaname Ohyama,Kenichiro Nakashima,Naotaka Kuroda. (2011-06-08) 4-Carbomethoxybenzaldehyde as a highly sensitive pre-column fluorescence derivatization reagent for 9,10-phenanthrenequinone.. Talanta, 85 ((1)): (809-812). [PMID:21645778] |
16. Dianne Lim,Akihiro Ikeda,Kennedy K-T Vu,Kent T Yamaguchi,Tim R Tyner,Alam S Hasson. (2011-10-26) Method development for the measurement of quinone levels in urine.. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879 ((30)): (3592-3598). [PMID:22024390] |
17. Di Xiao,Bo Pan,Min Wu,Ying Liu,Di Zhang,Hongbo Peng. (2011-11-08) Sorption comparison between phenanthrene and its degradation intermediates, 9,10-phenanthrenequinone and 9-phenanthrol in soils/sediments.. Chemosphere, 86 ((2)): (183-189). [PMID:22055310] |
18. Simon Trosien,Siegfried R Waldvogel. (2012-06-05) Synthesis of highly functionalized 9,10-phenanthrenequinones by oxidative coupling using MoCl5.. Organic letters, 14 ((12)): (2976-2979). [PMID:22655861] |
19. Manas Kumar Biswas,Sarat Chandra Patra,Amarendra Nath Maity,Shyue-Chu Ke,Nirmal Das Adhikary,Prasanta Ghosh. (2012-06-06) Electronic structures of ruthenium and osmium complexes of 9,10-phenanthrenequinone.. Inorganic chemistry, 51 ((12)): (6687-6699). [PMID:22663598] |
20. Tatsushi Toyooka,Takuya Shinmen,Jac M M J G Aarts,Yuko Ibuki. (2012-08-29) Dual effects of N-acetyl-L-cysteine dependent on NQO1 activity: suppressive or promotive of 9,10-phenanthrenequinone-induced toxicity.. Toxicology and applied pharmacology, 264 ((3)): (404-412). [PMID:22925602] |
21. Toshiyuki Matsunaga,Mika Hosogai,Marina Arakaki,Satoshi Endo,Ossama El-Kabbani,Akira Hara. (2012-09-15) 9,10-phenanthrenequinone induces monocytic differentiation of U937 cells through regulating expression of aldo-keto reductase 1C3.. Biological & pharmaceutical bulletin, 35 ((9)): (1598-1602). [PMID:22975515] |
22. Zahra Afrasiabi,Preston Stovall,Kristen Finley,Amitava Choudhury,Charles Barnes,Aamir Ahmad,Fazlul Sarkar,Alok Vyas,Subhash Padhye. (2013-06-19) Targeting triple negative breast cancer cells by N3-substituted 9,10-phenanthrenequinone thiosemicarbazones and their metal complexes.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 114 (114-119). [PMID:23770498] |
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