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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P408649-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $176.90 |
Sodium Channel Inhibitors
Specifications & Purity | Moligand™, 10mM in DMSO |
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Biochemical and Physiological Mechanisms | Phenytoin (Diphenylhydantoin) is an inactive voltage-gated sodium channel stabilizer. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Product Description | Information Phenytoin Phenytoin (Diphenylhydantoin) is an inactive voltage-gated sodium channel stabilizer. In vivo
cell lines:MM.1S, MM.1R, RPMI8226, U266, RPMI8266, RPMI-Dox40, OPM1 cells, primary MM cells and PBMNCs Concentrations: Incubation Time: Powder Purity:≥99% |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Canonical SMILES | O=C1NC(=O)C(N1)(C2=CC=CC=C2)C3=CC=CC=C3 |
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Molecular Weight | 252.27 |
Enter Lot Number to search for COA:
1. De Bai, Haowei Chen, Lijuan Liu, Nanxi Xiang, Jichuan Zhang, Chengyu Wu, Jiaheng Zhang, Fang Wang. (2024) Ionic liquid microcapsules for the topical delivery of pterostilbene: Enhanced transdermal delivery and anti-wrinkle and skin brightening effects. JOURNAL OF MOLECULAR LIQUIDS, 395 (123842). [PMID:] [10.1016/j.molliq.2023.123842] |
2. Yuxuan Lin, Weihua Qin, Yuwei Lu, Mingye Ren, Pan Gao, Feng Xiao, Shaoxia Yang. (2023) Reconstructing atomic Fe coordination in the PMS activation process to realize efficient BPA degradation at low temperature. Environmental Science-Nano, 10 (5): (1284-1296). [PMID:] [10.1039/D2EN01156E] |
3. Wei Li, Zhen Wang, Xiaoyu Wang, Xiaowei Cao, Caili Bi, Lili Jiang, Shuna Cui, Yong Liu. (2021) Risk prediction of drug-drug interaction potential of phenytoin and miconazole topical formulations. CHEMICO-BIOLOGICAL INTERACTIONS, 343 (109498). [PMID:33961833] [10.1016/j.cbi.2021.109498] |
4. Mengtian Jia, Yanyan Zhu, Dong Guo, Xiaogang Bi, Xiaohong Hou. (2020) Surface molecularly imprinted polymer based on core-shell Fe3O4@MIL-101(Cr) for selective extraction of phenytoin sodium in plasma. ANALYTICA CHIMICA ACTA, 1128 (211). [PMID:32825905] [10.1016/j.aca.2020.06.075] |
5. Jing-Xian Zhang, Mei-Juan Qi, Mei-Zhi Shi, Jun-Jun Chen, Xiang-Qi Zhang, Jiao Yang, Ke-Zhi Zhang, Yong-Long Han, Cheng Guo. (2018) Effects of Danhong injection, a traditional Chinese medicine, on nine cytochrome P450 isoforms in vitro. BIOMEDICAL CHROMATOGRAPHY, 33 (4): (e4454). [PMID:30520061] [10.1002/bmc.4454] |
6. Suqian Xu, Hanxu Zhu, Wenrui Cao, Zhibin Wen, Jinnan Wang, Corvini Philippe François-Xavier, Thomas Wintgens. (2018) Cu-Al2O3-g-C3N4 and Cu-Al2O3-C-dots with dual-reaction centres for simultaneous enhancement of Fenton-like catalytic activity and selective H2O2 conversion to hydroxyl radicals. APPLIED CATALYSIS B-ENVIRONMENTAL, 234 (223). [PMID:] [10.1016/j.apcatb.2018.04.029] |
7. Qing Wang,Jing Li,Xin Yang,Li Xu,Zhi-guo Shi,Lan-Ying Xu. (2014-08-17) Investigation on performance of zirconia and magnesia-zirconia stationary phases in hydrophilic interaction chromatography.. Talanta, 129 (438-447). [PMID:25127617] |
1. De Bai, Haowei Chen, Lijuan Liu, Nanxi Xiang, Jichuan Zhang, Chengyu Wu, Jiaheng Zhang, Fang Wang. (2024) Ionic liquid microcapsules for the topical delivery of pterostilbene: Enhanced transdermal delivery and anti-wrinkle and skin brightening effects. JOURNAL OF MOLECULAR LIQUIDS, 395 (123842). [PMID:] [10.1016/j.molliq.2023.123842] |
2. Yuxuan Lin, Weihua Qin, Yuwei Lu, Mingye Ren, Pan Gao, Feng Xiao, Shaoxia Yang. (2023) Reconstructing atomic Fe coordination in the PMS activation process to realize efficient BPA degradation at low temperature. Environmental Science-Nano, 10 (5): (1284-1296). [PMID:] [10.1039/D2EN01156E] |
3. Wei Li, Zhen Wang, Xiaoyu Wang, Xiaowei Cao, Caili Bi, Lili Jiang, Shuna Cui, Yong Liu. (2021) Risk prediction of drug-drug interaction potential of phenytoin and miconazole topical formulations. CHEMICO-BIOLOGICAL INTERACTIONS, 343 (109498). [PMID:33961833] [10.1016/j.cbi.2021.109498] |
4. Mengtian Jia, Yanyan Zhu, Dong Guo, Xiaogang Bi, Xiaohong Hou. (2020) Surface molecularly imprinted polymer based on core-shell Fe3O4@MIL-101(Cr) for selective extraction of phenytoin sodium in plasma. ANALYTICA CHIMICA ACTA, 1128 (211). [PMID:32825905] [10.1016/j.aca.2020.06.075] |
5. Jing-Xian Zhang, Mei-Juan Qi, Mei-Zhi Shi, Jun-Jun Chen, Xiang-Qi Zhang, Jiao Yang, Ke-Zhi Zhang, Yong-Long Han, Cheng Guo. (2018) Effects of Danhong injection, a traditional Chinese medicine, on nine cytochrome P450 isoforms in vitro. BIOMEDICAL CHROMATOGRAPHY, 33 (4): (e4454). [PMID:30520061] [10.1002/bmc.4454] |
6. Suqian Xu, Hanxu Zhu, Wenrui Cao, Zhibin Wen, Jinnan Wang, Corvini Philippe François-Xavier, Thomas Wintgens. (2018) Cu-Al2O3-g-C3N4 and Cu-Al2O3-C-dots with dual-reaction centres for simultaneous enhancement of Fenton-like catalytic activity and selective H2O2 conversion to hydroxyl radicals. APPLIED CATALYSIS B-ENVIRONMENTAL, 234 (223). [PMID:] [10.1016/j.apcatb.2018.04.029] |
7. Qing Wang,Jing Li,Xin Yang,Li Xu,Zhi-guo Shi,Lan-Ying Xu. (2014-08-17) Investigation on performance of zirconia and magnesia-zirconia stationary phases in hydrophilic interaction chromatography.. Talanta, 129 (438-447). [PMID:25127617] |