Phenytoin - 10mM in DMSO, high purity , CAS No.57-41-0(DMSO)

Item Number
P408649
Grouped product items
SKUSizeAvailabilityPrice Qty
P408649-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$176.90

Sodium Channel Inhibitors

Basic Description

Specifications & PurityMoligand™, 10mM in DMSO
Biochemical and Physiological MechanismsPhenytoin (Diphenylhydantoin) is an inactive voltage-gated sodium channel stabilizer.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™
Product Description

Information

Phenytoin Phenytoin (Diphenylhydantoin) is an inactive voltage-gated sodium channel stabilizer.
In vitro


In vivo


Cell Data

cell lines:MM.1S, MM.1R, RPMI8226, U266, RPMI8266, RPMI-Dox40, OPM1 cells, primary MM cells and PBMNCs

Concentrations:

Incubation Time:

Powder Purity:≥99%

Associated Targets(Human)

SCN2A Tclin Sodium channel protein type 2 subunit alpha (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Canonical SMILES O=C1NC(=O)C(N1)(C2=CC=CC=C2)C3=CC=CC=C3
Molecular Weight 252.27

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

Citations of This Product

1. De Bai, Haowei Chen, Lijuan Liu, Nanxi Xiang, Jichuan Zhang, Chengyu Wu, Jiaheng Zhang, Fang Wang.  (2024)  Ionic liquid microcapsules for the topical delivery of pterostilbene: Enhanced transdermal delivery and anti-wrinkle and skin brightening effects.  JOURNAL OF MOLECULAR LIQUIDS,  395  (123842).  [PMID:] [10.1016/j.molliq.2023.123842]
2. Yuxuan Lin, Weihua Qin, Yuwei Lu, Mingye Ren, Pan Gao, Feng Xiao, Shaoxia Yang.  (2023)  Reconstructing atomic Fe coordination in the PMS activation process to realize efficient BPA degradation at low temperature.  Environmental Science-Nano,  10  (5): (1284-1296).  [PMID:] [10.1039/D2EN01156E]
3. Wei Li, Zhen Wang, Xiaoyu Wang, Xiaowei Cao, Caili Bi, Lili Jiang, Shuna Cui, Yong Liu.  (2021)  Risk prediction of drug-drug interaction potential of phenytoin and miconazole topical formulations.  CHEMICO-BIOLOGICAL INTERACTIONS,  343  (109498).  [PMID:33961833] [10.1016/j.cbi.2021.109498]
4. Mengtian Jia, Yanyan Zhu, Dong Guo, Xiaogang Bi, Xiaohong Hou.  (2020)  Surface molecularly imprinted polymer based on core-shell Fe3O4@MIL-101(Cr) for selective extraction of phenytoin sodium in plasma.  ANALYTICA CHIMICA ACTA,  1128  (211).  [PMID:32825905] [10.1016/j.aca.2020.06.075]
5. Jing-Xian Zhang, Mei-Juan Qi, Mei-Zhi Shi, Jun-Jun Chen, Xiang-Qi Zhang, Jiao Yang, Ke-Zhi Zhang, Yong-Long Han, Cheng Guo.  (2018)  Effects of Danhong injection, a traditional Chinese medicine, on nine cytochrome P450 isoforms in vitro.  BIOMEDICAL CHROMATOGRAPHY,  33  (4): (e4454).  [PMID:30520061] [10.1002/bmc.4454]
6. Suqian Xu, Hanxu Zhu, Wenrui Cao, Zhibin Wen, Jinnan Wang, Corvini Philippe François-Xavier, Thomas Wintgens.  (2018)  Cu-Al2O3-g-C3N4 and Cu-Al2O3-C-dots with dual-reaction centres for simultaneous enhancement of Fenton-like catalytic activity and selective H2O2 conversion to hydroxyl radicals.  APPLIED CATALYSIS B-ENVIRONMENTAL,  234  (223).  [PMID:] [10.1016/j.apcatb.2018.04.029]
7. Qing Wang,Jing Li,Xin Yang,Li Xu,Zhi-guo Shi,Lan-Ying Xu.  (2014-08-17)  Investigation on performance of zirconia and magnesia-zirconia stationary phases in hydrophilic interaction chromatography..  Talanta,  129  (438-447).  [PMID:25127617]

References

1. De Bai, Haowei Chen, Lijuan Liu, Nanxi Xiang, Jichuan Zhang, Chengyu Wu, Jiaheng Zhang, Fang Wang.  (2024)  Ionic liquid microcapsules for the topical delivery of pterostilbene: Enhanced transdermal delivery and anti-wrinkle and skin brightening effects.  JOURNAL OF MOLECULAR LIQUIDS,  395  (123842).  [PMID:] [10.1016/j.molliq.2023.123842]
2. Yuxuan Lin, Weihua Qin, Yuwei Lu, Mingye Ren, Pan Gao, Feng Xiao, Shaoxia Yang.  (2023)  Reconstructing atomic Fe coordination in the PMS activation process to realize efficient BPA degradation at low temperature.  Environmental Science-Nano,  10  (5): (1284-1296).  [PMID:] [10.1039/D2EN01156E]
3. Wei Li, Zhen Wang, Xiaoyu Wang, Xiaowei Cao, Caili Bi, Lili Jiang, Shuna Cui, Yong Liu.  (2021)  Risk prediction of drug-drug interaction potential of phenytoin and miconazole topical formulations.  CHEMICO-BIOLOGICAL INTERACTIONS,  343  (109498).  [PMID:33961833] [10.1016/j.cbi.2021.109498]
4. Mengtian Jia, Yanyan Zhu, Dong Guo, Xiaogang Bi, Xiaohong Hou.  (2020)  Surface molecularly imprinted polymer based on core-shell Fe3O4@MIL-101(Cr) for selective extraction of phenytoin sodium in plasma.  ANALYTICA CHIMICA ACTA,  1128  (211).  [PMID:32825905] [10.1016/j.aca.2020.06.075]
5. Jing-Xian Zhang, Mei-Juan Qi, Mei-Zhi Shi, Jun-Jun Chen, Xiang-Qi Zhang, Jiao Yang, Ke-Zhi Zhang, Yong-Long Han, Cheng Guo.  (2018)  Effects of Danhong injection, a traditional Chinese medicine, on nine cytochrome P450 isoforms in vitro.  BIOMEDICAL CHROMATOGRAPHY,  33  (4): (e4454).  [PMID:30520061] [10.1002/bmc.4454]
6. Suqian Xu, Hanxu Zhu, Wenrui Cao, Zhibin Wen, Jinnan Wang, Corvini Philippe François-Xavier, Thomas Wintgens.  (2018)  Cu-Al2O3-g-C3N4 and Cu-Al2O3-C-dots with dual-reaction centres for simultaneous enhancement of Fenton-like catalytic activity and selective H2O2 conversion to hydroxyl radicals.  APPLIED CATALYSIS B-ENVIRONMENTAL,  234  (223).  [PMID:] [10.1016/j.apcatb.2018.04.029]
7. Qing Wang,Jing Li,Xin Yang,Li Xu,Zhi-guo Shi,Lan-Ying Xu.  (2014-08-17)  Investigation on performance of zirconia and magnesia-zirconia stationary phases in hydrophilic interaction chromatography..  Talanta,  129  (438-447).  [PMID:25127617]

Solution Calculators