Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | 3-(4-Hydroxyphenyl)propionic acid | 501-97-3 | Phloretic acid | 3-(4-Hydroxyphenyl)propanoic acid | desaminotyrosine | Hydro-p-coumaric acid | Benzenepropanoic acid, 4-hydroxy- | Dihydro-p-coumaric acid | 4-Hydroxyphenylpropionic acid | p-Hydroxyhydrocinnamic acid | 3-(p-Hyd |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
Associated Targets(Human)
DNMT1 Tclin DNA (cytosine-5)-methyltransferase 1 (0 Activities)
CSNK2A1 Tchem Casein kinase II subunit alpha (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
TAS2R39 Tchem Taste receptor type 2 member 39 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
PIK3CA Tclin Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
DNMT1 Tclin DNA (cytosine-5)-methyltransferase 1 (978 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CSNK2A1 Tchem Casein kinase II alpha (3512 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PIK3R1 Tchem PI3-kinase p110-alpha/p85-alpha (2589 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Associated Targets(non-human)
PIK3CA PI3-kinase p110-alpha subunit (51 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Plutella xylostella (1838 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Spodoptera exigua (540 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Phenol oxidase (19 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Names and Identifiers
| IUPAC Name | 3-(4-hydroxyphenyl)propanoic acid |
|---|---|
| INCHI | InChI=1S/C9H10O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-2,4-5,10H,3,6H2,(H,11,12) |
| InChi Key | NMHMNPHRMNGLLB-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC(=CC=C1CCC(=O)O)O |
| Isomeric SMILES | C1=CC(=CC=C1CCC(=O)O)O |
| WGK Germany | 3 |
| RTECS | MW5342000 |
| PubChem CID | 10394 |
| Molecular Weight | 166.17 |
| Beilstein | 2209841 |
| Reaxy-Rn | 2209841 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Melt Point(°C) | 130°C |
|---|
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. |
| WGK Germany | 3 |
| RTECS | MW5342000 |
| Reaxy-Rn | 2209841 |
Related Documents
Citations of This Product
| 1. Jingkai Liu, Liyue Zhang, Xinbei Zhu, Qing Chen, Kan Zhang, Xiaoqing Liu. (2023) Design of a Low-Temperature Ring-Opening Benzoxazine System Using a Supramolecular Hydrogen-Bond Structure. ACS Applied Polymer Materials, 5 (8): (6595–6606). [PMID:] [10.1021/acsapm.3c01107] |
| 2. Lili Hao, Shijia Zhao, Shiqi Hao, Yuxin He, Miao Feng, Ke Zhou, Yiyan He, Jiquan Yang, Hongli Mao, Zhongwei Gu. (2023) Functionalized gelatin-alginate based bioink with enhanced manufacturability and biomimicry for accelerating wound healing. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 240 (124364). [PMID:37044319] [10.1016/j.ijbiomac.2023.124364] |
| 3. Weicheng Cai, Zhaolin Li, Hui Huang, Xuejing Li, Jian Zhao, Pengbo Liu, Yajun Wu, Mingchang Liu, Jian Wang. (2023) A Compact UV-LED-Induced Fluorescence With Short Metal Capillary and Low Light Leakage: Application to Noninvasive Glucose Detection. IEEE SENSORS JOURNAL, 23 (8): (8366-8374). [PMID:] [10.1109/JSEN.2023.3257834] |
| 4. Peng Ding, Qianqian Wei, Ning Tian, Xiaoyue Ding, Ling Wang, Bin Wang, Oseweuba Valentine Okoro, Amin Shavandi, Lei Nie. (2022) Enzymatically crosslinked hydrogel based on tyramine modified gelatin and sialylated chitosan. Biomedical Materials, 18 (1): (15006). [PMID:36322975] [10.1088/1748-605X/ac9f90] |
| 5. Hui-Ying Wang, Cheng Qu, Meng-Ning Li, Chao-Ran Li, Run-Zhou Liu, Zifan Guo, Ping Li, Wen Gao, Hua Yang. (2022) Time-Series-Dependent Global Data Filtering Strategy for Mining and Profiling of Xenobiotic Metabolites in a Dynamic Complex Matrix: Application to Biotransformation of Flavonoids in the Extract of Ginkgo biloba by Gut Microbiota. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (45): (14386–14394). [PMID:36331925] [10.1021/acs.jafc.2c03080] |
| 6. Ru Xu, Dongdong Zhang, Ji Tan, Naijian Ge, Dan Liu, Junyu Liu, Liping Ouyang, Hongqin Zhu, Yuqin Qiao, Jiajun Qiu, Shijie Zhu, Xuanyong Liu. (2022) A multifunctional cascade bioreactor based on a layered double oxides composite hydrogel for synergetic tumor chemodynamic/starvation/photothermal therapy. Acta Biomaterialia, 153 (494). [PMID:36115653] [10.1016/j.actbio.2022.09.024] |
| 7. Peng Wei, Longlong Li, Li Wang, Jinfei Yan, Nan Zeng, Longxin Li, Nan Sun, Lu Bai, Helong Li, Yifeng Zhang. (2022) Synthesis and properties of high performance biobased liquid crystal copolyesters toward load-bearing bone repair application. EUROPEAN POLYMER JOURNAL, 173 (111278). [PMID:] [10.1016/j.eurpolymj.2022.111278] |
| 8. Yao Liu, Ruifang Sun, XiaoPing Lin, Lanlan Wu, Hengying Chen, Siwen Shen, Yan Li, Yuanhuan Wei, Guifang Deng. (2022) Procyanidins and its metabolites by gut microbiome improves insulin resistance in gestational diabetes mellitus mice model via regulating NF-κB and NLRP3 inflammasome pathway. BIOMEDICINE & PHARMACOTHERAPY, 151 (113078). [PMID:35567986] [10.1016/j.biopha.2022.113078] |
| 9. Qian Tao, Julong Zhong, Rui Wang, Yuzhu Huang. (2021) Ionic and Enzymatic Multiple-Crosslinked Nanogels for Drug Delivery. Polymers, 13 (20): (3565). [PMID:34685323] [10.3390/polym13203565] |
| 10. Feng Li, Liping Wang, Yilei Cai, Yihuo Luo, Xianai Shi. (2021) Safety assessment of desaminotyrosine: Acute, subchronic oral toxicity, and its effects on intestinal microbiota in rats. TOXICOLOGY AND APPLIED PHARMACOLOGY, 417 (115464). [PMID:33636197] [10.1016/j.taap.2021.115464] |
| 11. Yongheng Yin, Huimin Liu, Hongbo Li, Sheng Li, Hanfang Liu, Chongbin Wang, Chengyun Gao. (2020) Efficient sol-gel synthesis of zwitterion functionalized titania for nanofiltration membrane with enhanced selectivity and antifouling performance. Journal of the Taiwan Institute of Chemical Engineers, 111 (252). [PMID:] [10.1016/j.jtice.2020.05.003] |
| 12. Yang Li, Ying Peng, Ping Ma, Mengyue Wang, Chongsheng Peng, Pengfei Tu, Xiaobo Li. (2019) In vitro and in vivo metabolism of Cistanche tubulosa extract in normal and chronic unpredictable stress-induced depressive rats. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1125 (121728). [PMID:31352203] [10.1016/j.jchromb.2019.121728] |
| 13. Bo Chen, Jie Zhou, Qilu Meng, Yang Zhang, Shihua Zhang, Liang Zhang. (2018) Comparative analysis of fecal phenolic content between normal and obese rats after oral administration of tea polyphenols. Food & Function, 9 (9): (4858-4864). [PMID:30156246] [10.1039/C8FO00609A] |
| 14. Hong Liang, Xiaobing Chen, Rongrong Jin, Bowen Ke, Matthias Barz, Hua Ai, Yu Nie,. (2020-02-06) Integration of Indocyanine Green Analogs as Near-Infrared Fluorescent Carrier for Precise Imaging-Guided Gene Delivery.. Small (Weinheim an der Bergstrasse, Germany), 16 ((10)): ( e1906538-e1906538 ). [PMID:32022444] |
| 15. Yang Li,Ying Peng,Mengyue Wang,Pengfei Tu,Xiaobo Li. (2017-08-05) Human Gastrointestinal Metabolism of the Cistanches Herba Water Extract in Vitro: Elucidation of the Metabolic Profile Based on Comprehensive Metabolite Identification in Gastric Juice, Intestinal Juice, Human Intestinal Bacteria, and Intestinal Microsomes.. Journal of agricultural and food chemistry, 65 ((34)): (7447-7456). [PMID:28771352] |
References
| 1. Jingkai Liu, Liyue Zhang, Xinbei Zhu, Qing Chen, Kan Zhang, Xiaoqing Liu. (2023) Design of a Low-Temperature Ring-Opening Benzoxazine System Using a Supramolecular Hydrogen-Bond Structure. ACS Applied Polymer Materials, 5 (8): (6595–6606). [PMID:] [10.1021/acsapm.3c01107] |
| 2. Lili Hao, Shijia Zhao, Shiqi Hao, Yuxin He, Miao Feng, Ke Zhou, Yiyan He, Jiquan Yang, Hongli Mao, Zhongwei Gu. (2023) Functionalized gelatin-alginate based bioink with enhanced manufacturability and biomimicry for accelerating wound healing. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 240 (124364). [PMID:37044319] [10.1016/j.ijbiomac.2023.124364] |
| 3. Weicheng Cai, Zhaolin Li, Hui Huang, Xuejing Li, Jian Zhao, Pengbo Liu, Yajun Wu, Mingchang Liu, Jian Wang. (2023) A Compact UV-LED-Induced Fluorescence With Short Metal Capillary and Low Light Leakage: Application to Noninvasive Glucose Detection. IEEE SENSORS JOURNAL, 23 (8): (8366-8374). [PMID:] [10.1109/JSEN.2023.3257834] |
| 4. Peng Ding, Qianqian Wei, Ning Tian, Xiaoyue Ding, Ling Wang, Bin Wang, Oseweuba Valentine Okoro, Amin Shavandi, Lei Nie. (2022) Enzymatically crosslinked hydrogel based on tyramine modified gelatin and sialylated chitosan. Biomedical Materials, 18 (1): (15006). [PMID:36322975] [10.1088/1748-605X/ac9f90] |
| 5. Hui-Ying Wang, Cheng Qu, Meng-Ning Li, Chao-Ran Li, Run-Zhou Liu, Zifan Guo, Ping Li, Wen Gao, Hua Yang. (2022) Time-Series-Dependent Global Data Filtering Strategy for Mining and Profiling of Xenobiotic Metabolites in a Dynamic Complex Matrix: Application to Biotransformation of Flavonoids in the Extract of Ginkgo biloba by Gut Microbiota. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (45): (14386–14394). [PMID:36331925] [10.1021/acs.jafc.2c03080] |
| 6. Ru Xu, Dongdong Zhang, Ji Tan, Naijian Ge, Dan Liu, Junyu Liu, Liping Ouyang, Hongqin Zhu, Yuqin Qiao, Jiajun Qiu, Shijie Zhu, Xuanyong Liu. (2022) A multifunctional cascade bioreactor based on a layered double oxides composite hydrogel for synergetic tumor chemodynamic/starvation/photothermal therapy. Acta Biomaterialia, 153 (494). [PMID:36115653] [10.1016/j.actbio.2022.09.024] |
| 7. Peng Wei, Longlong Li, Li Wang, Jinfei Yan, Nan Zeng, Longxin Li, Nan Sun, Lu Bai, Helong Li, Yifeng Zhang. (2022) Synthesis and properties of high performance biobased liquid crystal copolyesters toward load-bearing bone repair application. EUROPEAN POLYMER JOURNAL, 173 (111278). [PMID:] [10.1016/j.eurpolymj.2022.111278] |
| 8. Yao Liu, Ruifang Sun, XiaoPing Lin, Lanlan Wu, Hengying Chen, Siwen Shen, Yan Li, Yuanhuan Wei, Guifang Deng. (2022) Procyanidins and its metabolites by gut microbiome improves insulin resistance in gestational diabetes mellitus mice model via regulating NF-κB and NLRP3 inflammasome pathway. BIOMEDICINE & PHARMACOTHERAPY, 151 (113078). [PMID:35567986] [10.1016/j.biopha.2022.113078] |
| 9. Qian Tao, Julong Zhong, Rui Wang, Yuzhu Huang. (2021) Ionic and Enzymatic Multiple-Crosslinked Nanogels for Drug Delivery. Polymers, 13 (20): (3565). [PMID:34685323] [10.3390/polym13203565] |
| 10. Feng Li, Liping Wang, Yilei Cai, Yihuo Luo, Xianai Shi. (2021) Safety assessment of desaminotyrosine: Acute, subchronic oral toxicity, and its effects on intestinal microbiota in rats. TOXICOLOGY AND APPLIED PHARMACOLOGY, 417 (115464). [PMID:33636197] [10.1016/j.taap.2021.115464] |
| 11. Yongheng Yin, Huimin Liu, Hongbo Li, Sheng Li, Hanfang Liu, Chongbin Wang, Chengyun Gao. (2020) Efficient sol-gel synthesis of zwitterion functionalized titania for nanofiltration membrane with enhanced selectivity and antifouling performance. Journal of the Taiwan Institute of Chemical Engineers, 111 (252). [PMID:] [10.1016/j.jtice.2020.05.003] |
| 12. Yang Li, Ying Peng, Ping Ma, Mengyue Wang, Chongsheng Peng, Pengfei Tu, Xiaobo Li. (2019) In vitro and in vivo metabolism of Cistanche tubulosa extract in normal and chronic unpredictable stress-induced depressive rats. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1125 (121728). [PMID:31352203] [10.1016/j.jchromb.2019.121728] |
| 13. Bo Chen, Jie Zhou, Qilu Meng, Yang Zhang, Shihua Zhang, Liang Zhang. (2018) Comparative analysis of fecal phenolic content between normal and obese rats after oral administration of tea polyphenols. Food & Function, 9 (9): (4858-4864). [PMID:30156246] [10.1039/C8FO00609A] |
| 14. Hong Liang, Xiaobing Chen, Rongrong Jin, Bowen Ke, Matthias Barz, Hua Ai, Yu Nie,. (2020-02-06) Integration of Indocyanine Green Analogs as Near-Infrared Fluorescent Carrier for Precise Imaging-Guided Gene Delivery.. Small (Weinheim an der Bergstrasse, Germany), 16 ((10)): ( e1906538-e1906538 ). [PMID:32022444] |
| 15. Yang Li,Ying Peng,Mengyue Wang,Pengfei Tu,Xiaobo Li. (2017-08-05) Human Gastrointestinal Metabolism of the Cistanches Herba Water Extract in Vitro: Elucidation of the Metabolic Profile Based on Comprehensive Metabolite Identification in Gastric Juice, Intestinal Juice, Human Intestinal Bacteria, and Intestinal Microsomes.. Journal of agricultural and food chemistry, 65 ((34)): (7447-7456). [PMID:28771352] |