Phloretin - ≥98%, high purity , CAS No.60-82-2, Inhibitor of AQP9;Channel blocker of ClC-3;Agonist of TAS2R14;Agonist of TAS2R39;Inhibitor of major facilitator superfamily domain containing 4B;Inhibitor of Sodium-dependent vitamin C transporter 1

Item Number

P127748

• Synonyms: phloretin|60-82-2|Dihydronaringenin|3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one|Phloretol|3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone|NSC 407292|1-Propanone, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-|MFCD00002288|beta-(
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Phloretin is an inhibitor of calcium channel protein, MCT1, MCT2, and PKC. It is the major polyphenol found in apple.Dihydrochalcones flavonoid. GLUT inhibitor. Active phlorizin metabolite. Blocks L-type Ca 2+ channels. Activates Ca 2+ -activated K + chan
• Storage Temp: Store at 2-8°C
• Shipped In: Wet ice
• Grade: Moligand™
• Action Type: AGONIST, CHANNEL BLOCKER, INHIBITOR
• Mechanism of action: Inhibitor of AQP9;Channel blocker of ClC-3;Agonist of TAS2R14;Agonist of TAS2R39;Inhibitor of major facilitator superfamily domain containing 4B;Inhibitor of Sodium-dependent vitamin C transporter 1
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Phloretin is a dihydrochalcone found in apple tree leaves, which shows beneficial effects on diabetes.
A calcium channel protein inhibitor.