Basic Description

Synonyms	1,3,5-Benzenetriol, anhydrous \| 1,5-Trihydroxycyclohexatriene \| Benzene, 1,3,5-trihydroxy- \| PHLOROGLUCINOL [WHO-DD] \| PHLOROGLUCINOL [EP MONOGRAPH] \| PHLOROGLUCINOL [INCI] \| Phloroglucinol, p.a., 99% \| AM84333 \| 1,3, 5-Trihydroxybenzene \| 1,3,5-benzenetr
Specifications & Purity	≥99%(HPLC)
Storage Temp	Protected from light,Room temperature,Argon charged,Desiccated
Shipped In	Normal
Product Description	Phloroglucinol is a hygroscopic biochemical that is also potentially useful for bone decalcification in microscopy specimens or the detection of wood fibers. A potentially useful hygroscopic biochemical.

Product Properties

ALogP	0.2

Associated Targets(Human)

TYR Tclin Tyrosinase (717 Activities)

Discover Target: TYR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)

Discover Target: PTGS1

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BACE1 Tchem Beta-secretase 1 (15641 Activities)

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HL-60 (67320 Activities)

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HT-1080 (3966 Activities)

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MRC5 (9203 Activities)

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POLK Tbio DNA polymerase kappa (8653 Activities)

Discover Target: POLK

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Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

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Crotalus adamanteus (3 Activities)

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RAW264.7 (28094 Activities)

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Vero (26788 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	benzene-1,3,5-triol
INCHI	InChI=1S/C6H6O3/c7-4-1-5(8)3-6(9)2-4/h1-3,7-9H
InChi Key	QCDYQQDYXPDABM-UHFFFAOYSA-N
Canonical SMILES	C1=C(C=C(C=C1O)O)O
Isomeric SMILES	C1=C(C=C(C=C1O)O)O
WGK Germany	2
PubChem CID	359
Molecular Weight	126.11
Beilstein	1341907

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

24 results found

Lot Number	Certificate Type	Date	Item
L2402179	Certificate of Analysis	Nov 12, 2024	P104096
K2426765	Certificate of Analysis	Nov 12, 2024	P104096
K2426761	Certificate of Analysis	Nov 12, 2024	P104096
K2426758	Certificate of Analysis	Nov 12, 2024	P104096
H2217597	Certificate of Analysis	May 11, 2024	P104096
H2217596	Certificate of Analysis	May 11, 2024	P104096
H2217518	Certificate of Analysis	May 11, 2024	P104096
H2217517	Certificate of Analysis	May 11, 2024	P104096
G2411148	Certificate of Analysis	May 06, 2024	P104096
G2411147	Certificate of Analysis	May 06, 2024	P104096
B2222382	Certificate of Analysis	Nov 20, 2023	P104096
B2223049	Certificate of Analysis	Nov 20, 2023	P104096
B2222383	Certificate of Analysis	Nov 20, 2023	P104096
B2222381	Certificate of Analysis	Nov 20, 2023	P104096
F2310471	Certificate of Analysis	May 31, 2023	P104096
F2310472	Certificate of Analysis	May 31, 2023	P104096
F2310463	Certificate of Analysis	May 31, 2023	P104096
F2310461	Certificate of Analysis	May 31, 2023	P104096
E2113377	Certificate of Analysis	Feb 10, 2023	P104096
E2113376	Certificate of Analysis	Feb 10, 2023	P104096
E2113370	Certificate of Analysis	Feb 10, 2023	P104096
E2113389	Certificate of Analysis	Feb 10, 2023	P104096
H2217516	Certificate of Analysis	Jul 28, 2022	P104096
E2428134	Certificate of Analysis	Apr 19, 2021	P104096

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Chemical and Physical Properties

Solubility	Soluble in water (10 g/l at 20 °C), ethanol, ether, pyridine, and methanol.
Sensitivity	Light & Moisture Sensitive
Boil Point(°C)	218°C
Melt Point(°C)	215-220 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H341:Suspected of causing genetic defects H412:Harmful to aquatic life with long lasting effects H317:May cause an allergic skin reaction H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P281:Use personal protective equipment as required. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	2
Class	6.1
Merck Index	7328

Alternative Products

Citations of This Product

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1. Qian Li,Jun Chen,Ti Li,Chengmei Liu,Yuxin Zhai,David Julian McClements,Jiyan Liu. (2015-10-08) Separation and characterization of polyphenolics from underutilized byproducts of fruit production (Choerospondias axillaris peels): inhibitory activity of proanthocyanidins against glycolysis enzymes.. Food & function, 6 ((12)): (3693-3701). [PMID:26442714]
2. Wenjie Ma, Gang Huang, Litao Yu, Xiaoqiang Miao, Xuguang An, Jing Zhang, Qingquan Kong, Qingyuan Wang, Weitang Yao. (2024) Synthesis of multi-cavity mesoporous carbon nanospheres through solvent-induced self-assembly: Anode material for sodium-ion batteries with long-term cycle stability. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 654 (6): (1447). [PMID:37922630] [10.1016/j.jcis.2023.10.135]
3. Haolin Zhang, Shiye Lin, Ruiwei Xie, Weizhi Zhong, Hui Wang, Mohamed A. Farag, Hidayat Hussain, Randolph R.J. Arroo, Xiaojia Chen, Jianbo Xiao. (2024) Thermal degradation of (2R, 3R)-dihydromyricetin in neutral aqueous solution at 100 ℃. FOOD CHEMISTRY, 435 (137560). [PMID:37793280] [10.1016/j.foodchem.2023.137560]
4. Xiang Jian Jun, Yuan Li Juan, Liao Qie Gen, Zhang Da Wen, Luo Lin Guang. (2023) Synthesis of azo-linked covalent organic polymers for pipette tip solid-phase extraction of sedative residues from animal tissues samples. ANALYTICAL SCIENCES, 39 (12): (1939-1946). [PMID:37584814] [10.1007/s44211-023-00406-5]
5. Hao Guan, Zhiyong Li, Qinlong Xu, Jingjing Meng, Kai Guo. (2023) Dual bio-based epoxy resin as green substitute for DGEBA analogue with high performances. REACTIVE & FUNCTIONAL POLYMERS, 191 (105687). [PMID:] [10.1016/j.reactfunctpolym.2023.105687]
6. Xuyan Ni, Jinqiu Zhou, Haoqing Ji, Yuejiao Chen, Huaming Yu, Yiwei Zheng, Tao Qian, Mengfan Wang, Libao Chen, Chenglin Yan. (2023) Excluding the Trouble from Interfacial Water by Covalent Organic Polymer to Realize Extremely Reversible Zn Anode. ADVANCED FUNCTIONAL MATERIALS, 33 (37): (2302293). [PMID:] [10.1002/adfm.202302293]
7. Dongdong Tan, Tianmiao Wang, Jing Hu, Donglian Deng, Tingting Li, Ruijun Li. (2023) Chiral covalent organic frameworks synthesized via a Suzuki–Miyaura-coupling reaction: enantioselective recognition of D/L-amino acids. NEW JOURNAL OF CHEMISTRY, 47 (13): (6378-6384). [PMID:] [10.1039/D2NJ05811A]
8. Min Zhang, Yiguo Jiang, Xiuquan Xu, Xiaofeng Yu, Wenyan Shen, Miaomiao Luo, Luyao Ding, Haiwen Chen. (2022) Facile synthesis of porous 1,3,5-Trihydroxybenzene substituted g-C3N4 for boosted photocatalytic Rhodamine B degradation and H2O2 production. JOURNAL OF ALLOYS AND COMPOUNDS, 925 (166604). [PMID:] [10.1016/j.jallcom.2022.166604]
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10. Yuen Wai Lui, Bun Chan, Matthew Y. Lui. (2021) Methylation with Dimethyl Carbonate/Dimethyl Sulfide Mixtures: An Integrated Process without Addition of Acid/Base and Formation of Residual Salts. ChemSusChem, 15 (3): (e202102538). [PMID:34907650] [10.1002/cssc.202102538]
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References

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33. Kosuke Sato,Yuya Oaki,Daisuke Takahashi,Kazunobu Toshima,Hiroaki Imai. (2015-02-14) Hierarchical CaCO3 chromatography: a stationary phase based on biominerals.. Chemistry (Weinheim an der Bergstrasse, Germany), 21 ((13)): (5034-5040). [PMID:25677568]
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Phloroglucinol Anhydrous - ≥99.0% (HPLC), high purity , CAS No.108-73-6

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