Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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P124619-100mg | 100mg | In stock | $562.90 | |
P124619-500mg | 500mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $2,530.90 |
Antifungal and antitumor anthraquinone
Synonyms | 1,8-dihydroxy-3-methoxy-6-methylanthracene- | NCGC00096075-02 | Rheochrysidin - Physcione | Emodin monomethyl ether | HMS3656I15 | MEGxm0_000018 | Spectrum2_000503 | 8,9-dihydroxy-3-methyl-6-methoxy-1,10-anthraquinone | AC-7979 | KS-5385 | Parienin | Phys |
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Specifications & Purity | Moligand™, ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Anthraquinone-derivative found in medicinal herbs.Antifungal and antitumor anthraquinone |
Storage Temp | Store at 2-8°C,Argon charged |
Shipped In | Wet ice |
Grade | Moligand™ |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description |
Physcion is an anthraquinone derivative and is available as the active constituent of Chinese medicinal plants such as Rhubarb, Polygonum cuspidatum and Reynoutria multiflora. It exhibits various biological activities such as antitumor, antimicrobial, antifungal, antioxidant and antihuman cytomegalovirus activity.
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 1,8-dihydroxy-3-methoxy-6-methylanthracene-9,10-dione |
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INCHI | InChI=1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3 |
InChi Key | FFWOKTFYGVYKIR-UHFFFAOYSA-N |
Canonical SMILES | CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)OC |
Isomeric SMILES | CC1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)OC |
WGK Germany | 3 |
RTECS | CB6720000 |
PubChem CID | 10639 |
Molecular Weight | 284.26 |
Beilstein | 6770499 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
G2431399 | Certificate of Analysis | Aug 06, 2024 | P124619 |
G2431400 | Certificate of Analysis | Aug 06, 2024 | P124619 |
L2308504 | Certificate of Analysis | Dec 15, 2023 | P124619 |
L2308505 | Certificate of Analysis | Dec 15, 2023 | P124619 |
G2201383 | Certificate of Analysis | Jul 08, 2022 | P124619 |
G2201387 | Certificate of Analysis | Jul 08, 2022 | P124619 |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. |
WGK Germany | 3 |
RTECS | CB6720000 |
1. Ke Hu, Rongyu Li, Feixu Mo, Yi Ding, Aiai Zhou, Xue Guo, Ruotong Li, Min Li, Minggui Ou, Ming Li. (2023) Natural product osthole can significantly disrupt cell wall integrity and dynamic balance of Fusarium oxysporum. PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 196 (24): (105623). [PMID:37945232] [10.1016/j.pestbp.2023.105623] |
2. Senlin Hou, Quancheng Liu, Hu Deng, Jun He, Wei Zhao, Zhixiang Wu, Qi Zhang, Liping Shang. (2023) Identification and low-frequency vibrational analysis of three free anthraquinones via terahertz spectroscopy. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 293 (122439). [PMID:36773425] [10.1016/j.saa.2023.122439] |
3. Rui Wang, Baifei Hu, Cheng Ye, Zhigang Zhang, Mingzhu Yin, Qiushi Cao, Yuanming Ba, Hongtao Liu. (2022) Stewed Rhubarb Decoction Ameliorates Adenine-Induced Chronic Renal Failure in Mice by Regulating Gut Microbiota Dysbiosis. Frontiers in Pharmacology, 13 (842720). [PMID:35392552] [10.3389/fphar.2022.842720] |
4. Ying Xu, Xuan Yu, Jiaqi Gui, Yiqun Wan, Jinping Chen, Ting Tan, Fan Liu, Lan Guo. (2022) Ultrasonic Solvent Extraction Followed by Dispersive Solid Phase Extraction (d-SPE) Cleanup for the Simultaneous Determination of Five Anthraquinones in Polygonum multiflorum by UHPLC-PDA. Foods, 11 (3): (386). [PMID:35159536] [10.3390/foods11030386] |
5. Sun Xiaodong, Chen Cheng, Li Xiaoqi, Du Yingxiang, Zhao Shiyuan, Feng Zijie. (2020) Gold nanoparticles coated with a tetramethylammonium lactobionate ionic liquid for enhanced chiral differentiation in open tubular capillary electrochromatography: application to enantioseparation of β-blockers. MICROCHIMICA ACTA, 187 (3): (1-8). [PMID:32060642] [10.1007/s00604-020-4121-2] |
6. Chi Chen, Zhuang Fu, Weiying Zhou, Qiushi Chen, Chenzhao Wang, Lu Xu, Zhibing Wang, Hanqi Zhang. (2020) Ionic liquid-immobilized NaY zeolite-based matrix solid phase dispersion for the extraction of active constituents in Rheum palmatum L.. MICROCHEMICAL JOURNAL, 152 (104245). [PMID:] [10.1016/j.microc.2019.104245] |
7. Jian Lu, Yingying Qin, Qi Zhang, Chao Yu, Yilin Wu, Yongsheng Yan, Hougang Fan, Minjia Meng, Chunxiang Li. (2019) Antibacterial, high-flux and 3D porous molecularly imprinted nanocomposite sponge membranes for cross-flow filtration of emodin from analogues. CHEMICAL ENGINEERING JOURNAL, 360 (483). [PMID:] [10.1016/j.cej.2018.12.014] |
8. Xiaoya Jiang, Xiaoyan Jiao, Doudou Zhang, Ligai Bai, Haiyan Liu, Hongyuan Yan. (2017) Fabrication of a polymer monolithic column via redox system and its application in efficient separation of Chinese herb Rheum palmatum L.. JOURNAL OF APPLIED POLYMER SCIENCE, 134 (21): [PMID:] [10.1002/app.44874] |
9. Dong Jian-Wei, Cai Le, Fang Yun-Shan, Duan Wei-He, Li Zhen-Jie, Ding Zhong-Tao. (2016) Simultaneous, Simple and Rapid Determination of Five Bioactive Free Anthraquinones in Radix et Rhizoma Rhei by Quantitative 1H NMR. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 27 (11): (2120-2126). [PMID:] [10.5935/0103-5053.20160103] |
10. Xingqiang Wu, Shuxuan Liang, Xusheng Ge, Yunkai Lv, Hanwen Sun. (2015) Synthesis and evaluation of dummy molecularly imprinted microspheres for the specific solid-phase extraction of six anthraquinones from slimming tea. JOURNAL OF SEPARATION SCIENCE, 38 (8): (1263-1270). [PMID:25677958] [10.1002/jssc.201401341] |
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