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Pioglitazone - ≥98%, high purity , CAS No.111025-46-8, Agonist of Peroxisome proliferator-activated receptor-γ;Channel blocker of TRPM3

Moligand™
≥98%

CAS#: 111025-46-8
Formula: C₁₉H₂₀N₂O₃S
Molecular Weight: 356.44
PubChem CID: 4829
PubChem SID: 488179857

Item Number

P129907

Grouped product items
SKU	Size	Availability	Price
P129907-50mg	50mg	In stock	$129.90
P129907-250mg	250mg	In stock	$585.90
P129907-1g	1g	In stock	$2,106.90
P129907-5g	5g	In stock	$9,477.90
P129907-25g	25g	In stock	$42,646.90

Selective PPARγ agonist

View related series

Peroxisome proliferator-activated receptor-γ Agonist TRPM3 Channel blocker

Basic Description

Synonyms	Pioglitazone\|111025-46-8\|Actos\|Glustin\|Zactos\|105355-27-9\|Pioglitazona\|Pioglitazonum\|5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione\|Pioglitazonum [INN-Latin]\|Pioglitazona [INN-Spanish]\|Piozone\|Pioglu\|U 72107\|AD-4833\|Pioglitazone (Actos)
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST, CHANNEL BLOCKER
Mechanism of action	Agonist of Peroxisome proliferator-activated receptor-γ;Channel blocker of TRPM3
Product Description	Pioglitazone (Actos) is a selective peroxisome proliferator-activated receptor gamma stimulator. A PPAR agonist with potential antidiabetic characteristics.

Associated Targets

TRPM3 Tchem Transient receptor potential cation channel subfamily M member 3 0 Activities

Discover Target: TRPM3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CA2 Tclin Carbonic anhydrase 2 1 Activities

Discover Target: CA2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ABCB11 Tchem Bile salt export pump 6 Activities

Discover Target: ABCB11

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAOB Tclin Amine oxidase [flavin-containing] B 4 Activities

Discover Target: MAOB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CISD1 Tchem CDGSH iron-sulfur domain-containing protein 1 1 Activities

Discover Target: CISD1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PPARG Tclin Peroxisome proliferator-activated receptor gamma 6 Activities

Discover Target: PPARG

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid	488179857
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488179857
IUPAC Name	5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
INCHI	InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)
InChi Key	HYAFETHFCAUJAY-UHFFFAOYSA-N
Canonical SMILES	CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
Isomeric SMILES	CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
Alternate CAS	112529-15-4
PubChem CID	4829
Molecular Weight	356.44

PubChem CID

ChEBI

CAS Registry No.

ChEMBL Ligand

DrugBank Ligand

BindingDB Ligand

Wikipedia

NURSA Ligand

PEP

DrugCentral Ligand

PubChem SID

Certificates

Certificate of Analysis(COA)

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12 results found

Lot Number	Certificate Type	Date	Item
C2401029	Certificate of Analysis	Jun 03, 2023	P129907
F23271048	Certificate of Analysis	Jun 03, 2023	P129907
F2327706	Certificate of Analysis	Jun 03, 2023	P129907
F2327707	Certificate of Analysis	Jun 03, 2023	P129907
F2327710	Certificate of Analysis	Jun 03, 2023	P129907
F2327801	Certificate of Analysis	Jun 03, 2023	P129907
F2327808	Certificate of Analysis	Jun 03, 2023	P129907
F2327817	Certificate of Analysis	Jun 03, 2023	P129907
F2327819	Certificate of Analysis	Jun 03, 2023	P129907
F2327820	Certificate of Analysis	Jun 03, 2023	P129907
F2327852	Certificate of Analysis	Jun 03, 2023	P129907
D1513136	Certificate of Analysis	Nov 16, 2022	P129907

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled H302+H312+H332:Harmful if swallowed, in contact with skin or if inhaled
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.

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