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Piroxicam - ≥98%(HPLC), high purity , CAS No.36322-90-4, Inhibitor of COX-1;Inhibitor of COX-2

Moligand™
≥98%(HPLC)

CAS#: 36322-90-4
Formula: C₁₅H₁₃N₃O₄S
Molecular Weight: 331.35
Beilstein Registry Number: 1876290
EC Number: 252-974-3
MDL number: MFCD00057317
PubChem CID: 54676228

Item Number

P129294

Grouped product items
SKU	Size	Availability	Price
P129294-1g	1g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$64.90
P129294-5g	5g	In stock	$140.90
P129294-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$634.90
P129294-100g	100g	In stock	$2,284.90
P129294-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$10,278.90

Reversible, selective cyclooxygenase-1 (COX-1) inhibitor

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Synonyms	piroxicam\|36322-90-4\|Feldene\|Piroxicamum\|Pyroxycam\|Roxicam\|Piroftal\|BAXO\|CP-16171\|Rosiden\|CHF 1251\|2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide\|4-Hydroxy-2-methyl-N-(pyridin-2-yl)-2H-benzo[e][1,2]thiazine-3-carboxamid
Specifications & Purity	≥98%(HPLC)
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of COX-1;Inhibitor of COX-2
Product Description	Piroxicam is a non-selective COX inhibitor with an IC50 of 6 mM. An inhibitor of prostaglandin synthesis as well as Cox-1 and Cox-2.

IUPAC Name	4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-yl-1λ6,2-benzothiazine-3-carboxamide
INCHI	InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)
InChi Key	QYSPLQLAKJAUJT-UHFFFAOYSA-N
Canonical SMILES	CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3
Isomeric SMILES	CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3
WGK Germany	3
RTECS	DL0705000
PubChem CID	54676228
Molecular Weight	331.35
Beilstein	1876290

DrugBank Ligand	DB00554
PubChem CID	54676228
CAS Registry No.	36322-90-4
ChEMBL Ligand	CHEMBL527
Wikipedia	Piroxicam
PEP	piroxicam
DrugCentral Ligand	2210

Lot Number	Certificate Type	Date	Item
F2214246	Certificate of Analysis	Mar 20, 2024	P129294
J2119553	Certificate of Analysis	Aug 17, 2023	P129294
J2119632	Certificate of Analysis	Aug 17, 2023	P129294
J2119637	Certificate of Analysis	Aug 17, 2023	P129294
J2119642	Certificate of Analysis	Aug 17, 2023	P129294
F1510086	Certificate of Analysis	Jan 20, 2023	P129294

Solubility	Soluble in water (Partly miscible), DMSO (25 mg/mL warm), ethanol (5 mg/mL warm), chloroform, ethyl acetate, DMF (~20 mg/mL), and 1:1 solution of DMSO:PBS(pH 7.2) (~0.5 mg/mL).
Sensitivity	Heat sensitive,air sensitive
Flash Point(°F)	123.8 °F
Flash Point(°C)	51 °C
Melt Point(°C)	198-200°C

Piroxicam - ≥98%(HPLC), high purity , CAS No.36322-90-4, Inhibitor of COX-1;Inhibitor of COX-2

Basic Description

Associated Targets

PTGS1 Tclin Prostaglandin G/H synthase 1 1 Activities

PTGS2 Tclin Prostaglandin G/H synthase 2 1 Activities

Names and Identifiers

Database links

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Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

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Pictogram(s)	GHS06, GHS08
Signal	Danger
Hazard Statements	H301:Toxic if swallowed H372:Causes damage to organs through prolonged or repeated exposure H360:May damage fertility or the unborn child H361:Suspected of damaging fertility or the unborn child
Precautionary Statements	P280:Wear protective gloves/protective clothing/eye protection/face protection. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P318:if exposed or concerned, get medical advice. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	DL0705000
Merck Index	7506