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PJ34 HCl - 10mM in DMSO, high purity , CAS No.344458-15-7
Potent, selective PARP-1 inhibitor
Basic Description Synonyms 344458-15-7 | PJ34 hydrochloride | PJ34 HCl | 2-(Dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridin-2-yl)acetamide hydrochloride | PJ 34 Hydrochloride | PARP Inhibitor VIII, PJ34 | PJ-34 HCl | PJ-34 hydrochloride | PJ34 (hydrochloride) | PJ 34 HCl | VHK9YBZ6SB | 2-(dimethylamino Specifications & Purity 10mM in DMSO Biochemical and Physiological Mechanisms PARP Inhibitor VIII, PJ34 is a cell-permeable, water-soluble phenanthridinone derivative which inhibits of poly(ADP-ribose) polymerase (PARP; EC50 = 20 nM). It is believed to be up to 10,000 times more potent than 3-aminobenzamide which has an EC = 200 μM Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Product Description PJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name 2-(dimethylamino)-N-(6-oxo-5H-phenanthridin-2-yl)acetamide;hydrochloride INCHI InChI=1S/C17H17N3O2.ClH/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15;/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22);1H InChi Key RURAZZMDMNRXMI-UHFFFAOYSA-N Canonical SMILES CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32.Cl Isomeric SMILES CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32.Cl WGK Germany 3 PubChem CID 16760621 Molecular Weight 331.8
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