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Plerixafor - 2mM in Water, high purity , CAS No.110078-46-1
Basic Description Synonyms Plerixafor|110078-46-1|Mozobil|AMD3100|1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene|Amd 3100|bicyclam JM-2987|SDZ SID 791|Plerixafor hydrochloride|plerixafor (amd3100)|AMD-3100|JM3100|plerixaforum|JKL 169|JM 3100|1-[[4-(1,4,8,11-tetrazacy Specifications & Purity Moligand™, 2mM in Water Biochemical and Physiological Mechanisms Plerixafor is a stem cell activator, and CXCR4 chemokine antagonis, Drug treatment of myeloma. Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Grade Moligand™ Product Description Plerixafor is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively. IC50 value: 44 nM (CXCR4); 5.7 nM (CXCL12-mediated chemotaxis) Target: CXCR4
Names and Identifiers IUPAC Name 1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane INCHI InChI=1S/C28H54N8/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36/h5-8,29-34H,1-4,9-26H2 InChi Key YIQPUIGJQJDJOS-UHFFFAOYSA-N Canonical SMILES C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3 Isomeric SMILES C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3 PubChem CID 65015 Molecular Weight 502.78
Chemical and Physical Properties Sensitivity air，Moisture，heat sensitive Melt Point(°C) 133 °C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
Precautionary Statements P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P264: Wash hands [and …] thoroughly after handling.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
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