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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P136483-5mg | 5mg | In stock | $75.90 | |
P136483-10mg | 10mg | In stock | $107.90 | |
P136483-25mg | 25mg | In stock | $195.90 | |
P136483-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $303.90 | |
P136483-100mg | 100mg | In stock | $489.90 |
Dual ERK1/RasGAP inhibitor. Maintains ESC self-renewal
Synonyms | Pluripotin|839707-37-8|N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide|SC1(Pluripotin)|CHEMBL4213673|N-(3-(7-((1,3-dimethyl-1H-pyrazol-5-yl)amino)-1-meth |
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Specifications & Purity | ≥98% (HPLC) |
Storage Temp | Store at -20°C |
Shipped In | Dry ice |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | N-[3-[7-[(2,5-dimethylpyrazol-3-yl)amino]-1-methyl-2-oxo-4H-pyrimido[4,5-d]pyrimidin-3-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide |
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INCHI | InChI=1S/C27H25F3N8O2/c1-15-8-9-20(32-24(39)17-6-5-7-19(11-17)27(28,29)30)12-21(15)38-14-18-13-31-25(34-23(18)36(3)26(38)40)33-22-10-16(2)35-37(22)4/h5-13H,14H2,1-4H3,(H,32,39)(H,31,33,34) |
InChi Key | NBZFRTJWEIHFPF-UHFFFAOYSA-N |
Canonical SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)N3CC4=CN=C(N=C4N(C3=O)C)NC5=CC(=NN5C)C |
Isomeric SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)N3CC4=CN=C(N=C4N(C3=O)C)NC5=CC(=NN5C)C |
WGK Germany | 3 |
PubChem CID | 12003241 |
UN Number | 2811 |
Packing Group | II |
Molecular Weight | 550.54 |
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Lot Number | Certificate Type | Date | Item |
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Certificate of Analysis | Apr 03, 2024 | P136483 | |
Certificate of Analysis | Apr 03, 2024 | P136483 | |
Certificate of Analysis | Apr 03, 2024 | P136483 | |
Certificate of Analysis | Apr 03, 2024 | P136483 | |
Certificate of Analysis | Apr 03, 2024 | P136483 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 13.76, Max Conc. mM: 25 |
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Pictogram(s) | GHS06 |
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Signal | Danger |
Hazard Statements | H301 |
Precautionary Statements | P321,P405,P501,P264,P270,P330,P301+P316 |
WGK Germany | 3 |
Class | 6.1 |