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PMPA (NMDA antagonist) , CAS No.113919-36-1
Competitive NMDA antagonist
Basic Description Synonyms J-003041 | HY-107698 | Pmpa(nmda antagonist) | 4-(PHOSPHONOMETHYL)PIPERAZINE-2-CARBOXYLIC ACID | PD079296 | NCGC00159547-01 | 2-Piperazinecarboxylic acid, 4-(phosphonomethyl)- | AKOS024457022 | PMPA (NMDA antagonist) | SCHEMBL1999794 | DTXSID30590848 | 4- Biochemical and Physiological Mechanisms Competitive NMDA receptor antagonist. Displays Kivalues of 0.84, 2.74, 3.53 and 4.16μM at GluN2A, GluN2B, GluN2C and GluN2D subunit-containing receptors respectively. Selective over AMPA receptors.Please refer toIUPHAR Guide to Pharmacologyfor the most re Storage Temp Store at 2-8°C Shipped In Wet ice
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name 4-(phosphonomethyl)piperazine-2-carboxylic acid INCHI InChI=1S/C6H13N2O5P/c9-6(10)5-3-8(2-1-7-5)4-14(11,12)13/h5,7H,1-4H2,(H,9,10)(H2,11,12,13) InChi Key ILRBBHJXTYIHTP-UHFFFAOYSA-N Canonical SMILES C1CN(CC(N1)C(=O)O)CP(=O)(O)O Isomeric SMILES C1CN(CC(N1)C(=O)O)CP(=O)(O)O PubChem CID 17756792 Molecular Weight 224.15
Chemical and Physical Properties Solubility Solvent:water, Max Conc. mg/mL: 22.42, Max Conc. mM: 100
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