Wnt signaling pathway blocker. Inhibits Wnt/β-catenin pathway. Blocks the protein-protein interaction between β-catenin and TCF. Antitumor effects.PNU-74654 inhibits the Wnt-β catenin pathway by blocking the interaction between β-catenin and TCF (T cell f
Storage Temp
Store at -80°C
Shipped In
Ice chest + Ice pads
Product Description
application：
PNU-74654 has been used:
as a β-catenin signaling inhibitor to study its effects on the funnel cartilage differentiation in Sepia sp. embryos
as a Wnt signaling inhibitor to study its effects on glycogen synthase kinase 3β (GSK-3β) inhibition in prostate cancer cell lines
as a Wnt signaling inhibitor to study its effects on leptin-induced cell proliferation in breast cancer cells
