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Podophyllotoxin - 98%, high purity , CAS No.518-28-5

≥98%

CAS#: 518-28-5
Formula: C₂₂H₂₂O₈
Molecular Weight: 414.41
Beilstein Registry Number: 99163
EC Number: 208-250-4
MDL number: MFCD00075290
PubChem CID: 10607

Item Number

P105536

Grouped product items
SKU	Size	Availability	Price
P105536-500mg	500mg	In stock	$78.90
P105536-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$142.90
P105536-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$639.90
P105536-25g	25g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$2,879.90

Potent, competitive microtubule assembly inhibitor

View related series

Aromatic polyketide Phenylpropanoids

Basic Description

Synonyms	podophyllotoxin\|Podofilox\|518-28-5\|Condylox\|Condyline\|(-)-Podophyllotoxin\|Podophyllotoxin 7\|Podophyllinic acid lactone\|Wartec\|Warticon\|Podofilm\|Podofilox [USAN]\|Podophilox\|CCRIS 565\|HSDB 7238\|EINECS 208-250-4\|NSC 24818\|NSC-24818\|DTXSID3045645\|UNII-L36H50F
Specifications & Purity	98%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice

Associated Targets

CYP3A4 Tclin Cytochrome P450 3A4 1 Activities

Discover Target: CYP3A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor 1 Activities

Discover Target: NR3C1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	(5R,5aR,8aR,9R)-5-hydroxy-9-(3,4,5-trimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
INCHI	InChI=1S/C22H22O8/c1-25-16-4-10(5-17(26-2)21(16)27-3)18-11-6-14-15(30-9-29-14)7-12(11)20(23)13-8-28-22(24)19(13)18/h4-7,13,18-20,23H,8-9H2,1-3H3/t13-,18+,19-,20-/m0/s1
InChi Key	YJGVMLPVUAXIQN-XVVDYKMHSA-N
Canonical SMILES	COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O
Isomeric SMILES	COC1=CC(=CC(=C1OC)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](C4=CC5=C(C=C24)OCO5)O
WGK Germany	3
RTECS	LV2500000
PubChem CID	10607
UN Number	3462
Molecular Weight	414.41
Beilstein	99163

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

6 results found

Lot Number	Certificate Type	Date	Item
G2207394	Certificate of Analysis	Aug 23, 2021	P105536
G2207395	Certificate of Analysis	Aug 23, 2021	P105536
G2207396	Certificate of Analysis	Aug 23, 2021	P105536
G2207397	Certificate of Analysis	Aug 23, 2021	P105536
G2207459	Certificate of Analysis	Aug 23, 2021	P105536
H2117335	Certificate of Analysis	Aug 23, 2021	P105536

Sensitivity

Heat Sensitive

Specific Rotation[α]

-129° (C=1,CHCl3)

Melt Point(°C)

178-184°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed H310:Fatal in contact with skin
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P262:Do not get in eyes, on skin, or on clothing. P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	LV2500000
Merck Index	7546

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