Grouped product items

SKU

Size

Availability

Price

Qty

P477776-50mg

50mg

Available within 8-12 weeks(?)

$800.90

P477776-100mg

100mg

Available within 8-12 weeks(?)

$1,434.90

Basic Description

Synonyms	DL-Proline\|609-36-9\|pyrrolidine-2-carboxylic acid\|H-DL-Pro-OH\|Proline, DL-\|Proline DL-form\|2-Pyrrolidine carboxylic acid\|MFCD00005250\|Prolin\|Hpro\|(+/-)-Pyrrolidine-2-carboxylic acid\|NSC97923\|DCS9E77JPQ\|D-Proline-13C5,15N\|CHEMBL72275\|25191-13-3\|DTXSID90411
Specifications & Purity	mol wt 1,000-10,000
Biochemical and Physiological Mechanisms	Poly-L-Proline is an antigenic homopolymer.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets

RUNX1 Tbio Runt-related transcription factor 1 0 Activities

Discover Target: RUNX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

POLK Tbio DNA polymerase kappa 0 Activities

Discover Target: POLK

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIN1 Tclin Glutamate receptor ionotropic, NMDA 1 0 Activities

Discover Target: GRIN1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	pyrrolidine-2-carboxylic acid
INCHI	InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)
InChi Key	ONIBWKKTOPOVIA-UHFFFAOYSA-N
Canonical SMILES	C1CC(NC1)C(=O)O
Isomeric SMILES	C1CC(NC1)C(=O)O
PubChem CID	614
Molecular Weight	115.13(Monomer)

Certificates

Certificate of Analysis(COA)

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3 results found

Lot Number	Certificate Type	Date	Item
D2419437	Certificate of Analysis	Apr 11, 2024	P477776
D2419438	Certificate of Analysis	Apr 11, 2024	P477776
D2419439	Certificate of Analysis	Apr 11, 2024	P477776

Alternative Products

References

1. Manos Gkikas,Hermis Iatrou,Nikolaos S Thomaidis,Paschalis Alexandridis,Nikos Hadjichristidis. (2011-05-17) Well-defined homopolypeptides, copolypeptides, and hybrids of poly(l-proline).. Biomacromolecules, 12 ((6)): (2396-2406). [PMID:21568310]
2. M Rubert,M Monjo,S P Lyngstadaas,J M Ramis. (2012-07-12) Effect of alginate hydrogel containing polyproline-rich peptides on osteoblast differentiation.. Biomedical materials (Bristol, England), 7 ((5)): (055003-055003). [PMID:22782012]
3. Charles W Bugg,J Mario Isas,Torsten Fischer,Paul H Patterson,Ralf Langen. (2012-07-18) Structural features and domain organization of huntingtin fibrils.. The Journal of biological chemistry, 287 ((38)): (31739-31746). [PMID:22801429]
4. Noemi G Mirkin,Samuel Krimm. (2012-07-19) Water interaction differences determine the relative energetic stability of the polyproline II conformation of the alanine dipeptide in aqueous environments.. Biopolymers, 97 ((10)): (789-794). [PMID:22806498]
5. Michael A Purdy. (2012-07-20) Evolution of the hepatitis E virus polyproline region: order from disorder.. Journal of virology, 86 ((18)): (10186-10193). [PMID:22811526]
6. Kevser Biberoglu,Lawrence M Schopfer,Ozden Tacal,Oksana Lockridge. (2012-08-15) The proline-rich tetramerization peptides in equine serum butyrylcholinesterase.. The FEBS journal, 279 ((20)): (3844-3858). [PMID:22889087]
7. Madhurima Das,Gautam Basu. (2012-09-20) Glycine rescue of β-sheets from cis-proline.. Journal of the American Chemical Society, 134 ((40)): (16536-16539). [PMID:22989233]
8. Xing Zhang,Ryan R Julian. (2012-11-01) Photoinitiated intramolecular diradical cross-linking of polyproline peptides in the gas phase.. Physical chemistry chemical physics : PCCP, 14 ((47)): (16243-16249). [PMID:23111659]
9. Nico J de Mol,John A W Kruijtzer,Ed E Moret,Isabelle Broutin,Rob M J Liskamp. (2012-11-20) Unusual binding of Grb2 protein to a bivalent polyproline-ligand immobilized on a SPR sensor: intermolecular bivalent binding.. Biochimica et biophysica acta, 1834 ((2)): (524-535). [PMID:23159538]
10. Sonali B Rohamare,Vaishali Dixit,Pavan Kumar Nareddy,D Sivaramakrishna,Musti J Swamy,Sushama M Gaikwad. (2012-12-29) Polyproline fold-In imparting kinetic stability to an alkaline serine endopeptidase.. Biochimica et biophysica acta, 1834 ((3)): (708-716). [PMID:23270996]
11. Stefania Conti,Giorgia Radicioni,Tecla Ciociola,Renato Longhi,Luciano Polonelli,Rita Gatti,Tiziana Cabras,Irene Messana,Massimo Castagnola,Alberto Vitali. (2013-01-01) Structural and functional studies on a proline-rich peptide isolated from swine saliva endowed with antifungal activity towards Cryptococcus neoformans.. Biochimica et biophysica acta, 1828 ((3)): (1066-1074). [PMID:23274276]
12. W Austin Elam,Travis P Schrank,Andrew J Campagnolo,Vincent J Hilser. (2013-01-24) Evolutionary conservation of the polyproline II conformation surrounding intrinsically disordered phosphorylation sites.. Protein science : a publication of the Protein Society, 22 ((4)): (405-417). [PMID:23341186]
13. W Austin Elam,Travis P Schrank,Andrew J Campagnolo,Vincent J Hilser. (2013-01-29) Temperature and urea have opposing impacts on polyproline II conformational bias.. Biochemistry, 52 ((5)): (949-958). [PMID:23350874]
14. Kevser Biberoglu,Lawrence M Schopfer,Ashima Saxena,Ozden Tacal,Oksana Lockridge. (2013-01-29) Polyproline tetramer organizing peptides in fetal bovine serum acetylcholinesterase.. Biochimica et biophysica acta, 1834 ((4)): (745-753). [PMID:23352838]
15. Alexander A Morgan,Edward Rubenstein. (2013-02-02) Proline: the distribution, frequency, positioning, and common functional roles of proline and polyproline sequences in the human proteome.. PloS one, 8 ((1)): (e53785-e53785). [PMID:23372670]
16. Christopher J Woolstenhulme,Shankar Parajuli,David W Healey,Diana P Valverde,E Nicholas Petersen,Agata L Starosta,Nicholas R Guydosh,W Evan Johnson,Daniel N Wilson,Allen R Buskirk. (2013-02-23) Nascent peptides that block protein synthesis in bacteria.. Proceedings of the National Academy of Sciences of the United States of America, 110 ((10)): (E878-E887). [PMID:23431150]
17. Alexei A Adzhubei,Michael J E Sternberg,Alexander A Makarov. (2013-03-20) Polyproline-II helix in proteins: structure and function.. Journal of molecular biology, 425 ((12)): (2100-2132). [PMID:23507311]
18. Robert W Newberry,Ronald T Raines. (2013-07-31) n→π* interactions in poly(lactic acid) suggest a role in protein folding.. Chemical communications (Cambridge, England), 49 ((70)): (7699-7701). [PMID:23897514]
19. Nicholas Stephane Caron,Carly Robyn Desmond,Jianrun Xia,Ray Truant. (2013-07-31) Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin.. Proceedings of the National Academy of Sciences of the United States of America, 110 ((36)): (14610-14615). [PMID:23898200]
20. Sebastien Lhomme,Cyril Garrouste,Nassim Kamar,Karine Saune,Florence Abravanel,Jean-Michel Mansuy,Martine Dubois,Lionel Rostaing,Jacques Izopet. (2013-08-22) Influence of polyproline region and macro domain genetic heterogeneity on HEV persistence in immunocompromised patients.. The Journal of infectious diseases, 209 ((2)): (300-303). [PMID:23964111]
21. Sebastien Lhomme,Florence Abravanel,Martine Dubois,Karine Sandres-Saune,Jean-Michel Mansuy,Lionel Rostaing,Nassim Kamar,Jacques Izopet. (2014-08-08) Characterization of the polyproline region of the hepatitis E virus in immunocompromised patients.. Journal of virology, 88 ((20)): (12017-12025). [PMID:25100839]
22. Edoardo Del Poggetto,Fabrizio Chiti,Francesco Bemporad. (2015-08-01) The Folding process of Human Profilin-1, a novel protein associated with familial amyotrophic lateral sclerosis.. Scientific reports, 5 (12332-12332). [PMID:26227615]
23. Lucía B Chemes,Leonardo G Alonso,María G Noval,Gonzalo de Prat-Gay. (2012-07-05) Circular dichroism techniques for the analysis of intrinsically disordered proteins and domains.. Methods in molecular biology (Clifton, N.J.), 895 (387-404). [PMID:22760329]
24. Conor C G Scully,Vishal Rai,Gennadiy Poda,Serge Zaretsky,Darcy C Burns,R Scott Houliston,Tiantong Lou,Andrei K Yudin. (2012-11-06) Bending rigid molecular rods: formation of oligoproline macrocycles.. Chemistry (Weinheim an der Bergstrasse, Germany), 18 ((49)): (15612-15617). [PMID:23124621]
25. Manuel E Patarroyo,Armando Moreno-Vranich,Adriana Bermúdez. (2012-11-13) Phi (Φ) and psi (Ψ) angles involved in malarial peptide bonds determine sterile protective immunity.. Biochemical and biophysical research communications, 429 ((1-2)): (75-80). [PMID:23142598]
26. Susanne Ude,Jürgen Lassak,Agata L Starosta,Tobias Kraxenberger,Daniel N Wilson,Kirsten Jung. (2012-12-15) Translation elongation factor EF-P alleviates ribosome stalling at polyproline stretches.. Science (New York, N.Y.), 339 ((6115)): (82-85). [PMID:23239623]
27. Allen R Buskirk,Rachel Green. (2013-01-05) Biochemistry. Getting past polyproline pauses.. Science (New York, N.Y.), 339 ((6115)): (38-39). [PMID:23288527]
28. Emmanuel B Naziga,Frank Schweizer,Stacey D Wetmore. (2013-02-01) Solvent interactions stabilize the polyproline II conformation of glycosylated oligoprolines.. The journal of physical chemistry. B, 117 ((9)): (2671-2681). [PMID:23363073]
29. Yolanda Pérez,Mariano Maffei,Ana Igea,Irene Amata,Margarida Gairí,Angel R Nebreda,Pau Bernadó,Miquel Pons. (2013-02-19) Lipid binding by the Unique and SH3 domains of c-Src suggests a new regulatory mechanism.. Scientific reports, 3 (1295-1295). [PMID:23416516]
30. Siobhan Toal,Derya Meral,Daniel Verbaro,Brigita Urbanc,Reinhard Schweitzer-Stenner. (2013-03-02) pH-Independence of trialanine and the effects of termini blocking in short peptides: a combined vibrational, NMR, UVCD, and molecular dynamics study.. The journal of physical chemistry. B, 117 ((14)): (3689-3706). [PMID:23448349]
31. Bindu Ambaru,Anupriya Gopalsamy,T V Satish Tammana,Hosahalli S Subramanya,Chhitar M Gupta. (2020-05-15) Actin sequestering protein, profilin, regulates intracellular vesicle transport in Leishmania.. Molecular and biochemical parasitology, 238 (111280-111280). [PMID:32407750]
32. M Ashtari,N M Cann. (2012-10-17) Poly-proline-based chiral stationary phases: a molecular dynamics study of triproline, tetraproline, pentaproline and hexaproline interfaces.. Journal of chromatography. A, 1265 (70-87). [PMID:23068764]

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Poly-L-proline - mol wt 1,000-10,000, high purity , CAS No.25191-13-3