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Polyuridylic acid potassium salt - 98%, high purity , CAS No.27416-86-0
a single-stranded RNA model compound
Basic Description Synonyms Uridine 5'-monophosphate|5'-URIDYLIC ACID|Uridylic acid|58-97-9|Uridine monophosphate|uridine-5'-monophosphate|Uridine phosphate|Uridine 5'-phosphoric acid|Uridine 5'-phosphate|5'-UMP|UMP|UMP (nucleic acid)|Uridine 5'-(dihydrogen phosphate)|5'Uridylic aci Specifications & Purity ≥98% Storage Temp Store at -20°C Shipped In Ice chest + Ice pads Product Description Polyuridylic acid potassium salt is a single-stranded RNA model compound often in comparison with other ssRNA model oligonucleotides such as Poly(I) and Poly(C) to study processes that are dependent upon ssRNA regulation such as Toll-like receptor regulation. Poly(U) is used as an effective agonist for TLR7.
Names and Identifiers IUPAC Name [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate INCHI InChI=1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 InChi Key DJJCXFVJDGTHFX-XVFCMESISA-N Canonical SMILES C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O Isomeric SMILES C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O WGK Germany 3 PubChem CID 6030
Chemical and Physical Properties Solubility Soluble in water (20 mg/ml), and 0.1 N KPO4 buffer, pH 7.0 (10 mg/ml).
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L2315451