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Polyuridylic acid potassium salt - 98%, high purity , CAS No.27416-86-0

4 Citations

≥98%

CAS#: 27416-86-0
PubChem CID: 6030

Item Number

P350073

Grouped product items
SKU	Size	Availability	Price
P350073-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$119.90
P350073-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$237.90
P350073-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$427.90

a single-stranded RNA model compound

Basic Description

Synonyms	Uridine 5'-monophosphate \| 5'-URIDYLIC ACID \| Uridylic acid \| 58-97-9 \| Uridine monophosphate \| uridine-5'-monophosphate \| Uridine phosphate \| Uridine 5'-phosphoric acid \| Uridine 5'-phosphate \| 5'-UMP \| UMP \| UMP (nucleic acid) \| Uridine 5'-(dihydrogen phosphate) \| 5'Uridylic aci
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	Polyuridylic acid potassium salt is a single-stranded RNA model compound often in comparison with other ssRNA model oligonucleotides such as Poly(I) and Poly(C) to study processes that are dependent upon ssRNA regulation such as Toll-like receptor regulation. Poly(U) is used as an effective agonist for TLR7.

Associated Targets(Human)

CRBN Tclin Protein cereblon (0 Activities)

Discover Target: CRBN

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RGS4 Tchem Regulator of G-protein signaling 4 (0 Activities)

Discover Target: RGS4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)

Discover Target: TDP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AGO2 Tbio Protein argonaute-2 (0 Activities)

Discover Target: AGO2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

UMPS Tclin Uridine 5'-monophosphate synthase (0 Activities)

Discover Target: UMPS

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CMPK1 Tchem UMP-CMP kinase (0 Activities)

Discover Target: CMPK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

P2RY6 Tchem P2Y purinoceptor 6 (0 Activities)

Discover Target: P2RY6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

P2RY6 Tchem Pyrimidinergic receptor P2Y6 (717 Activities)

Discover Target: P2RY6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

UMPS Tclin Uridine 5'-monophosphate synthase (20 Activities)

Discover Target: UMPS

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CMPK1 Tchem UMP-CMP kinase (152 Activities)

Discover Target: CMPK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)

Discover Target: RGS4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CRBN Tclin Protein cereblon (139 Activities)

Discover Target: CRBN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AGO2 Tbio Protein argonaute-2 (21 Activities)

Discover Target: AGO2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

ompdc Orotidine phosphate decarboxylase (9 Activities)

Discover Target: ompdc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

pyrF Orotidine 5'-phosphate decarboxylase (39 Activities)

Discover Target: pyrF

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
INCHI	InChI=1S/C9H13N2O9P/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChi Key	DJJCXFVJDGTHFX-XVFCMESISA-N
Canonical SMILES	C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O
Isomeric SMILES	C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O
WGK Germany	3
PubChem CID	6030

Certificates

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6 results found

Lot Number	Certificate Type	Date	Item
L2315451	Certificate of Analysis	Dec 01, 2023	P350073
L2315452	Certificate of Analysis	Dec 01, 2023	P350073
L2315453	Certificate of Analysis	Dec 01, 2023	P350073
L2315454	Certificate of Analysis	Dec 01, 2023	P350073
L2315455	Certificate of Analysis	Dec 01, 2023	P350073
L2315456	Certificate of Analysis	Dec 01, 2023	P350073

Citations of This Product

1. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin. (2023) A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation. ANALYTICAL SCIENCES, (1-7). [PMID:37843729]
2. Xu Shichao, Wu Haifeng, Liu Siyuan, Du Peidong, Wang Hui, Yang Haijun, Xu Wenjie, Chen Shuangming, Song Li, Li Jikun, Shi Xinghua, Wang Zhen-Gang. (2023) A supramolecular metalloenzyme possessing robust oxidase-mimetic catalytic function. Nature Communications, 14 (1): (1-14). [PMID:37419896]
3. Peidong Du, Yanzhe Shen, Baoli Zhang, Shan Li, Minzheng Gao, Ting Wang, Xiaokang Ding, Bingran Yu, Zhen-Gang Wang, Fu-Jian Xu. (2023) A H2O2-Supplied Supramolecular Material for Post-irradiated Infected Wound Treatment. Advanced Science, 10 (9): (2206851). [PMID:36709479]
4. Yuqin Wang, Pingping Fan, Shanyu Zhang, Liying Wang, Xinyue Li, Wendong Jia, Yao Liu, Kefan Wang, Xiaoyu Du, Panke Zhang, Shuo Huang. (2022) Discrimination of Ribonucleoside Mono-, Di-, and Triphosphates Using an Engineered Nanopore. ACS Nano, 16 (12): (21356–21365). [PMID:36475606]

References

1. Lai Liang, Zhang Mengyun, Liu Chusheng, Qu Jiahuan, Xu Dongsheng, Jiang Zhengjin. (2023) A comprehensive evaluation of a polymeric zwitterionic hydrophilic monolith for nucleotide separation. ANALYTICAL SCIENCES, (1-7). [PMID:37843729]
2. Xu Shichao, Wu Haifeng, Liu Siyuan, Du Peidong, Wang Hui, Yang Haijun, Xu Wenjie, Chen Shuangming, Song Li, Li Jikun, Shi Xinghua, Wang Zhen-Gang. (2023) A supramolecular metalloenzyme possessing robust oxidase-mimetic catalytic function. Nature Communications, 14 (1): (1-14). [PMID:37419896]
3. Peidong Du, Yanzhe Shen, Baoli Zhang, Shan Li, Minzheng Gao, Ting Wang, Xiaokang Ding, Bingran Yu, Zhen-Gang Wang, Fu-Jian Xu. (2023) A H2O2-Supplied Supramolecular Material for Post-irradiated Infected Wound Treatment. Advanced Science, 10 (9): (2206851). [PMID:36709479]
4. Yuqin Wang, Pingping Fan, Shanyu Zhang, Liying Wang, Xinyue Li, Wendong Jia, Yao Liu, Kefan Wang, Xiaoyu Du, Panke Zhang, Shuo Huang. (2022) Discrimination of Ribonucleoside Mono-, Di-, and Triphosphates Using an Engineered Nanopore. ACS Nano, 16 (12): (21356–21365). [PMID:36475606]

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