PPT - 97%, high purity , CAS No.263717-53-9, Agonist of Estrogen receptor-α

Item Number

P274988

• Synonyms: 4-(1,5-bis(4-hydroxyphenyl)-4-propyl-1,2-dihydro-3H-pyrazol-3-ylidene)cyclohexa-2,5-dien-1-one | 4-[2,5-BIS(4-HYDROXYPHENYL)-4-PROPYLPYRAZOL-3-YL]PHENOL | C24H22N2O3 | BP162642 | HMS2233O06 | CCG-204664 | SR-01000075913-3 | NCGC00015511-06 | NCGC00015511-
• Specifications & Purity: Moligand™, ≥97%
• Biochemical and Physiological Mechanisms: Potent, subtype selective ERα estrogen receptor agonist. Over 400-fold selective for ERα over ERβ receptors.
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: AGONIST
• Mechanism of action: Agonist of Estrogen receptor-α
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Introduction:

Roquinimex (Linomide; PNU212616; ABR212616) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and reduces the secretion of TNF alpha.