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Praeruptorin A - 10mM in DMSO, high purity , CAS No.73069-25-7

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Praeruptorin A - 10mM in DMSO, high purity , CAS No.73069-25-7

10mM in DMSO

CAS#: 73069-25-7
Formula: C₂₁H₂₂O₇
Molecular Weight: 386.4
PubChem CID: 38347601

Item Number

P425703

Grouped product items
SKU	Size	Availability	Price	Qty
P425703-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$95.90

Calcium Channel Inhibitors

Basic Description

Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	Praeruptorin A, a naturally existing pyranocumarin, is isolated from the dried root of Peucedanum praeruptorum Dunn. Praeruptorin A inhibits p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca2+ oscillation. Praeruptorin A can significantly upregulates
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads
Product Description	Information Praeruptorin A Praeruptorin A, a naturally existing pyranocumarin, is isolated from the dried root of Peucedanum praeruptorum Dunn. Praeruptorin A inhibits p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca2+ oscillation. Praeruptorin A can significantly upregulates multidrug resistance-associated protein 2 expression via the constitutive androstane receptor-mediated pathway in vitro, and this should be taken as an herb-drug interaction. Targets Akt ; p38 MAPK ; Ca2+

Associated Targets(Human)

TNFSF11 Tclin Tumor necrosis factor ligand superfamily member 11 (138 Activities)

Discover Target: TNFSF11

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Mus musculus (284745 Activities)

Discover Target:

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CALM Calmodulin (71 Activities)

Discover Target: CALM

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	[(9R,10S)-10-acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl] (Z)-2-methylbut-2-enoate
INCHI	InChI=1S/C21H22O7/c1-6-11(2)20(24)27-19-18(25-12(3)22)16-14(28-21(19,4)5)9-7-13-8-10-15(23)26-17(13)16/h6-10,18-19H,1-5H3/b11-6-/t18-,19+/m0/s1
InChi Key	XGPBRZDOJDLKOT-CIRUDOSSSA-N
Canonical SMILES	CC=C(C)C(=O)OC1C(C2=C(C=CC3=C2OC(=O)C=C3)OC1(C)C)OC(=O)C
Isomeric SMILES	C/C=C(/C)\C(=O)O[C@@H]1[C@H](C2=C(C=CC3=C2OC(=O)C=C3)OC1(C)C)OC(=O)C
PubChem CID	38347601
Molecular Weight	386.4

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Chemical and Physical Properties

Sensitivity	light sensitive

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