Praeruptorin B - 98%, high purity , CAS No.81740-07-0

  • ≥98%
Item Number
P414391
Grouped product items
SKUSizeAvailabilityPrice Qty
P414391-1mg
1mg
In stock
$42.90
P414391-5mg
5mg
In stock
$76.90
P414391-25mg
25mg
In stock
$233.90
P414391-100mg
100mg
Available within 1-2 weeks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$666.90

Fatty Acid Synthase Inhibitors

Basic Description

SynonymsPraeruptorin B | 81740-07-0 | [8,8-dimethyl-9-[(E)-2-methylbut-2-enoyl]oxy-2-oxo-9,10-dihydropyrano[2,3-f]chromen-10-yl] (E)-2-methylbut-2-enoate | (+/-)-Praeruptorin B | (-)-Praeruptorin B | 73069-26-8 | Praeruptorin-B | SCHEMBL3380751 | CHEMBL3596578 | 4970-26-7 | AKOS015
Specifications & Purity≥98%
Biochemical and Physiological MechanismsPraeruptorin B is an important compound isolated from Bai-hua Qian-hu and has been reported to exert multiple biochemical and pharmacological activities.praeruptorin B exerts lipid-lowering effects through inhibits SREBPs and could serve as a possible the
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Information

Praeruptorin B Praeruptorin B is an important compound isolated from Bai-hua Qian-hu and has been reported to exert multiple biochemical and pharmacological activities.praeruptorin B exerts lipid-lowering effects through inhibits SREBPs and could serve as a possible therapeutic option to improve hyperlipidemia and hyperlipidemia-induced comorbidities.

Associated Targets(non-human)

Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
norA Quinolone resistance protein norA (2171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
mdeA Fluoroquinolone resistance protein (28 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488195338
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488195338
IUPAC Name [8,8-dimethyl-9-[(E)-2-methylbut-2-enoyl]oxy-2-oxo-9,10-dihydropyrano[2,3-f]chromen-10-yl] (E)-2-methylbut-2-enoate
INCHI InChI=1S/C24H26O7/c1-7-13(3)22(26)29-20-18-16(11-9-15-10-12-17(25)28-19(15)18)31-24(5,6)21(20)30-23(27)14(4)8-2/h7-12,20-21H,1-6H3/b13-7+,14-8+
InChi Key PNTWXEIQXBRCPS-FNCQTZNRSA-N
Canonical SMILES CC=C(C)C(=O)OC1C(C(OC2=C1C3=C(C=C2)C=CC(=O)O3)(C)C)OC(=O)C(=CC)C
Isomeric SMILES C/C=C(\C)/C(=O)OC1C(C(OC2=C1C3=C(C=C2)C=CC(=O)O3)(C)C)OC(=O)/C(=C/C)/C
PubChem CID 5319259
Molecular Weight 426.5

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Certificate of Analysis(COA)

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8 results found

Lot NumberCertificate TypeDateItem
D2320392Certificate of AnalysisMar 16, 2023 P414391
D2320427Certificate of AnalysisMar 16, 2023 P414391
D2320430Certificate of AnalysisMar 16, 2023 P414391
D2320434Certificate of AnalysisMar 16, 2023 P414391
D2320497Certificate of AnalysisMar 16, 2023 P414391
D2320506Certificate of AnalysisMar 16, 2023 P414391
D2320509Certificate of AnalysisMar 16, 2023 P414391
D2320515Certificate of AnalysisMar 16, 2023 P414391

Chemical and Physical Properties

SolubilitySolubility (25°C) In vitro DMSO: 32 mg/mL (75.03 mM);    

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Solution Calculators