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pregnanolone sulphate , CAS No.1477-67-4

CAS#: 1477-67-4
PubChem CID: 44322229

Item Number

P612916

Grouped product items
SKU	Size	Availability	Price	Qty
P612916-25μg	25μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,190.90
P612916-100μg	100μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,334.90

Basic Description

Synonyms	pregnanolone sulphate \| CHEMBL1179566 \| 3alpha-Hydroxy-5beta-pregnane-20-one sulfate \| pregnanolone sulfate \| SCHEMBL782131 \| GTPL11535 \| CHEBI:166778 \| BDBM50498439 \| 3alpha-hydroxy-5beta-pregnan-20-one sulfate \| 3 alpha-hydroxy-5 beta-pregnan-20-one sulfate \| 3alpha-hydrox
Specifications & Purity	Moligand™
Grade	Moligand™

Associated Targets(Human)

GRIN2A Tclin Glutamate [NMDA] receptor subunit epsilon 1 (112 Activities)

Discover Target: GRIN2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GRIN2B Tclin Glutamate [NMDA] receptor subunit epsilon 2 (467 Activities)

Discover Target: GRIN2B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GRIN2C Tclin Glutamate [NMDA] receptor subunit epsilon 3 (47 Activities)

Discover Target: GRIN2C

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GRIN1 Tclin Glutamate NMDA receptor; GRIN1/GRIN2B (726 Activities)

Discover Target: GRIN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	[(3R,5R,8R,9S,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate
INCHI	InChI=1S/C21H34O5S/c1-13(22)17-6-7-18-16-5-4-14-12-15(26-27(23,24)25)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19H,4-12H2,1-3H3,(H,23,24,25)/t14-,15-,16+,17-,18+,19+,20+,21-/m1/s1
InChi Key	MENQCIVHHONJLU-YZRLXODZSA-N
Canonical SMILES	CC(=O)[C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CC[C@H]2[C@]1(C)CC[C@H](C2)OS(=O)(=O)O
Isomeric SMILES	CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)OS(=O)(=O)O)C)C
PubChem CID	44322229

PubChem CID

CAS Registry No.

BindingDB Ligand

ChEMBL Ligand

References

1. Burnell ES, Irvine M, Fang G, Sapkota K, Jane DE, Monaghan DT. (2019) Positive and Negative Allosteric Modulators of N-Methyl-d-aspartate (NMDA) Receptors: Structure-Activity Relationships and Mechanisms of Action.. J Med Chem, 62 (1): (3-23). [PMID:29446949]
2. Park-Chung M, Wu FS, Farb DH. (1994) 3 alpha-Hydroxy-5 beta-pregnan-20-one sulfate: a negative modulator of the NMDA-induced current in cultured neurons.. Mol Pharmacol, 46 (1): (146-50). [PMID:7520124]

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pregnanolone sulphate , CAS No.1477-67-4

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Names and Identifiers

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Certificates

Certificate of Analysis(COA)

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References

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