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Pregnenolone sulfate sodium salt - 98%, high purity , CAS No.1852-38-6

≥98%

CAS#: 1852-38-6
Formula: C₂₁H₃₁NaO₅S
Molecular Weight: 418.52
PubChem CID: 23676306

Item Number

P287521

Grouped product items
SKU	Size	Availability	Price	Qty
P287521-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$39.90
P287521-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$119.90

NMDA potentiator; also GABAAinhibitor and TRPM3 activator

View related series

Autophagy Endogenous Metabolite NMDA Receptor Modulators

Basic Description

Synonyms	SCHEMBL1321009\|3b-Hydroxy-5-pregnen-20-one monosulfate sodium salt\|Pregnenolone monosulfate (sodium salt)\|3-Hydroxy-5-pregnen-20-one monosulfate (sodium salt)\|DTXSID80635475\|HY-110189\|Pregnenolone monosulfate sodium salt\|BAA85238\|Pregnenolone monosulfate
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Highly potent neurosteroid with multiple actions. Enhances intracellular Ca2+upon NMDA receptor-mediated synaptic activity (EC50~ 2 pM) and potentiates NMDA responses. Inhibitor at GABAAreceptors (IC50values are 0.4 to >300 μM, depending on specific subun
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads

Associated Targets

GMNN Tbio Geminin 0 Activities

Discover Target: GMNN

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SNCA Tchem Alpha-synuclein 0 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SMAD3 Tchem Mothers against decapentaplegic homolog 3 0 Activities

Discover Target: SMAD3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

Discover Target: IDH1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	sodium;[(3S,8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] sulfate
INCHI	InChI=1S/C21H32O5S.Na/c1-13(22)17-6-7-18-16-5-4-14-12-15(26-27(23,24)25)8-10-20(14,2)19(16)9-11-21(17,18)3;/h4,15-19H,5-12H2,1-3H3,(H,23,24,25);/q;+1/p-1/t15-,16-,17+,18-,19-,20-,21+;/m0./s1
InChi Key	QQVJEIZJHDPTSH-UTNKIXDHSA-M
Canonical SMILES	CC(=O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OS(=O)(=O)[O-])C)C.[Na+]
Isomeric SMILES	CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)OS(=O)(=O)[O-])C)C.[Na+]
PubChem CID	23676306
Molecular Weight	418.52

Certificates

Certificate of Analysis(COA)

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4 results found

Lot Number	Certificate Type	Date	Item
D2403465	Certificate of Analysis	Mar 14, 2024	P287521
D2403466	Certificate of Analysis	Mar 14, 2024	P287521
D2403467	Certificate of Analysis	Mar 14, 2024	P287521
D2403468	Certificate of Analysis	Mar 14, 2024	P287521

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