pregnenolone sulphate , CAS No.1247-64-9, Antagonist of glycine receptor α1 subunit;Antagonist of glycine receptor α2 subunit;Antagonist of glycine receptor β subunit;Activator of TRPM1;Activator of TRPM3

Item Number

P612918

Grouped product items
SKU	Size	Availability	Price	Qty
P612918-25μg	25μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
P612918-100μg	100μg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,334.90

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Basic Description

Synonyms	CMC_13403 \| BDBM50503144 \| UNII-04Y4D91RG0 \| PREGS \| Pregnenolone monosulfate \| [3H]pregnenolone sulphate \| LUZRJRNZXALNLM-JGRZULCMSA-N \| 20-oxopregn-5-en-3beta-yl sulfate \| C18044 \| Pregn-5-en-20-one-3beta-yl sulfate Pregnenolone 3-sulfate \| 20-Oxopregn-
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	ACTIVATOR, ANTAGONIST
Mechanism of action	Antagonist of glycine receptor α1 subunit;Antagonist of glycine receptor α2 subunit;Antagonist of glycine receptor β subunit;Activator of TRPM1;Activator of TRPM3

Associated Targets(Human)

TRPM1 Tchem Transient receptor potential cation channel subfamily M member 1 (0 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TRPM3 Tchem Transient receptor potential cation channel subfamily M member 3 (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLRA2 Tchem Glycine receptor subunit alpha-2 (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLRA1 Tclin Glycine receptor subunit alpha-1 (1 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLRB Tclin Glycine receptor subunit beta (2 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GRIN2A Tclin Glutamate [NMDA] receptor subunit epsilon 1 (112 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GRIN2B Tclin Glutamate [NMDA] receptor subunit epsilon 2 (467 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GRIN2C Tclin Glutamate [NMDA] receptor subunit epsilon 3 (47 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Grin2d Glutamate [NMDA] receptor subunit epsilon 4 (130 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	[(3S,8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate
INCHI	InChI=1S/C21H32O5S/c1-13(22)17-6-7-18-16-5-4-14-12-15(26-27(23,24)25)8-10-20(14,2)19(16)9-11-21(17,18)3/h4,15-19H,5-12H2,1-3H3,(H,23,24,25)/t15-,16-,17+,18-,19-,20-,21+/m0/s1
InChi Key	DIJBBUIOWGGQOP-QGVNFLHTSA-N
Canonical SMILES	CC(=O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)OS(=O)(=O)O)C)C
Isomeric SMILES	CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)OS(=O)(=O)O)C)C
Alternate CAS	1247-64-9
PubChem CID	105074
MeSH Entry Terms	5-pregnen-3 beta-ol-20-one sulfate;pregnenolone sulfate;pregnenolone sulfate, (3alpha)-isomer;pregnenolone sulfate, sodium salt, (3beta)-isomer