Grouped product items

SKU

Size

Availability

Price

Qty

A638754-250mg

250mg

Available within 8-12 weeks(?)

$52.90

A638754-1g

Available within 8-12 weeks(?)

$126.90

A638754-5g

Available within 8-12 weeks(?)

$239.90

A638754-25g

25g

Available within 8-12 weeks(?)

$588.90

Basic Description

Synonyms	1-Ethyl-3-(3-dimethyllaminopropyl)carbodiimide hydrochloride \| 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride \| EDC·HCl \| EDAC·HCL \| EDCI·HCl
Storage Temp	Store at -20°C,Argon charged,Desiccated
Shipped In	Ice chest + Ice pads
Product Description	Product introduction： Premium Grade EDC is our highest quality formulation of this popular carbodiimide crosslinker, specially characterized for applications where product integrity and risk minimization are paramount. Features of Premium Grade EDC: • EDC—carbodiimide crosslinker for conjugation between carboxylates and amines • High quality—identity and purity confirmed by several tests • Product integrity—enhanced level of testing and characterization compared to standard grade • Lot retention—ample supply of past lots retained to ensure future process testing • Change management—Change Control Notification (CCN) service • Consistent manufacture—batch-specific manufacturing documentation review Compared to the standard grade product, Premium Grade EDC provides more clearly defined quality and product support by including (a) increased analytical testing and product characterization, (b) greater batch-specific information and quality assurance review, (c) extensive lot sample retention and (d) change control notification. EDC is 1-ethyl-3-[3-dimethylaminopropyl]carbodiimide hydrochloride, a water-soluble carbodiimide crosslinker that activates carboxyl groups for spontaneous reaction with primary amines, enabling peptide immobilization and hapten-carrier protein conjugation. In the presence of N-hydroxysulfosuccinimide (sulfo-NHS), EDC can be used to convert carboxyl groups to amine-reactive sulfo-NHS esters. This is accomplished by mixing the EDC with a carboxyl containing molecule and adding sulfo-NHS. Specifications of Premium Grade EDC We manufacture crosslinking reagents to ensure the highest possible overall product integrity, consistency and performance for the intended research applications. • Visual: White crystalline powder, free of foreign matter • Identity: IR scan shows only peaks characteristic of EDC • Water content: Karl Fischer titration, ≤ 2% • Trace metals: All metals, including lead, ≤ 50 ppm • Elemental analysis: Reported values for C, H, and N Applications: • Conjugate carboxyl and amino groups among peptides and proteins • Couple haptens to immunogenic carrier proteins (e.g.,attach a peptide to KLH) •Immobilize peptide antigens to affinity-purify antibodies • Create NHS-activated, amine-reactive labeling compounds • Crosslink proteins to carboxyl coated beads or surfaces • Activate nanoparticles with amine-reactive sulfo-NHS esters Product References: Crosslinker Application Guide -- search for recent literature references for this product • Reactive Moiety:Carbodiimide • Crosslinker Type:Heterobifunctional • Form:Solid: • Spacer:Short(<10 Å) • Labeling Method:Chemical Labeling • Spacer Arm Length:0.0 Å

Names and Identifiers

INCHI	InChI=1S/C8H17N3.ClH/c1-4-9-8-10-6-5-7-11(2)3;/h4-7H2,1-3H3;1H
InChi Key	FPQQSJJWHUJYPU-UHFFFAOYSA-N
Canonical SMILES	CCN=C=NCCCN(C)C.Cl
Isomeric SMILES	CCN=C=NCCCN(C)C.Cl
WGK Germany	3
RTECS	FF2200000
Alternate CAS	7084-11-9
PubChem CID	2723939
Molecular Weight	191.70
Beilstein	5764110
Reaxy-Rn	5764110

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

4 results found

Lot Number	Certificate Type	Date	Item
A2416088	Certificate of Analysis	Jan 05, 2024	A638754
A2416089	Certificate of Analysis	Jan 05, 2024	A638754
A2416090	Certificate of Analysis	Jan 05, 2024	A638754
A2416091	Certificate of Analysis	Jan 05, 2024	A638754

Chemical and Physical Properties

Solubility	Soluble in acetonitrile dichloromethane, dimethylformamide, and tetrahydrofuran. Slightly soluble in water.
Sensitivity	Moisture sensitive; Heat sensitive
Melt Point(°C)	115-118°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06, GHS08, GHS09, GHS05, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H311:Toxic in contact with skin H373:Causes damage to organs through prolonged or repeated exposure H302:Harmful if swallowed H318:Causes serious eye damage H317:May cause an allergic skin reaction H400:Very toxic to aquatic life H410:Very toxic to aquatic life with long lasting effects
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P391:Collect spillage. P330:Rinse mouth. P361+P364:Take off immediately all contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P317:Get emergency medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	FF2200000
Reaxy-Rn	5764110

Alternative Products

References

1. Jiachuan Yang. (2022) Novel Fluorescent Nanocellulose Hydrogel Based on Nanocellulose and Carbon Dots for Detection and Removal of Heavy Metal Ions in Water. Foods, 11 (11): (1619). [PMID:]

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Premium-Grade EDC , CAS No.25952-53-8

Basic Description

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Alternative Products

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

SKU	Size	Availability	Price
A638754-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$52.90
A638754-1g	1g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$126.90
A638754-5g	5g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$239.90
A638754-25g	25g	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$588.90