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PRL-3 inhibitor - 95%, high purity , CAS No.893449-38-2
a cell permeable benzylidene rhodanine compound
Basic Description Synonyms PRL-3 Inhibitor | 893449-38-2 | CHEMBL207958 | 5-(5-Bromo-2-((2-bromobenzyl)oxy)benzylidene)-2-thioxothiazolidin-4-one | PRL-3 Inhibitor I | 5-[[5-bromo-2-[(2-bromophenyl)methoxy]phenyl]methylene]-2-thioxo-4-thiazolidinone | 1-(2-Bromobenzyloxy)-4-bromo-2-benzylidene Specifications & Purity ≥95% Storage Temp Protected from light,Store at -20°C Shipped In Ice chest + Ice pads Product Description PRL-3 Inhibitor is a cell-permeable benzylidene rhodanine compound that potently inhibits PRL-3 (hPRL-3), a member of the regenerating liver family tyrosine phosphatases. PRL-3 Inhibitor has been shown to reduce the invasiveness of murine melanoma B16F10 cells.
Associated Targets(Human) Associated Targets(non-human) Names and Identifiers IUPAC Name (5Z)-5-[[5-bromo-2-[(2-bromophenyl)methoxy]phenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one INCHI InChI=1S/C17H11Br2NO2S2/c18-12-5-6-14(22-9-10-3-1-2-4-13(10)19)11(7-12)8-15-16(21)20-17(23)24-15/h1-8H,9H2,(H,20,21,23)/b15-8- InChi Key HXNBAOLVPAWYLT-NVNXTCNLSA-N Canonical SMILES C1=CC=C(C(=C1)COC2=C(C=C(C=C2)Br)C=C3C(=O)NC(=S)S3)Br Isomeric SMILES C1=CC=C(C(=C1)COC2=C(C=C(C=C2)Br)/C=C\3/C(=O)NC(=S)S3)Br PubChem CID 11983303 UN Number 3077 Packing Group III Molecular Weight 485.21
Chemical and Physical Properties Solubility Soluble in DMSO (5 mg/ml). Slight warming may be necessary for complete solubilization. Sensitivity light sensitive Refractive Index n20D1.77 (Predicted) Boil Point(°C) 620.54° C (Predicted) Melt Point(°C) 268.90° C (Predicted)
Safety and Hazards(GHS) Pictogram(s) GHS09 , GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
H400: Very toxic to aquatic life
H410: Very toxic to aquatic life with long lasting effects
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P391: Collect spillage.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
Class 9
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