Procainamide hydrochloride - 98%, high purity , Sodium channel alpha subunit blocker, CAS No.614-39-1, Sodium channel alpha subunit blocker

Item Number

P171174

Grouped product items
SKU	Size	Availability	Price	Qty
P171174-5g	5g	In stock	$96.90

Sodium channel blocker. Specific DNA methyltransferase 1 inhibitor.

Basic Description

Synonyms	procainamide hydrochloride\|614-39-1\|Procainamide Hcl\|Pronestyl\|Procapan\|Procanbid\|Procan\|Procan SR\|4-amino-N-[2-(diethylamino)ethyl]benzamide hydrochloride\|Pronestyl-Sr\|Procainhydrochlorid\|Procainii chloridum\|Promide hydrochloride\|Amidoprocaine\|Cardiorytm
Specifications & Purity	98%
Storage Temp	Protected from light,Room temperature,Argon charged
Shipped In	Normal
Action Type	BLOCKER
Mechanism of action	Sodium channel alpha subunit blocker
Product Description	Product Application: Procainamide hydrochloride (PAH) is suitable to investigate its binding behavior with human serum albumin and bovine serum albumin by fluorescence quenching study to understand the pharmacokinetic and pharmacodynamic mechanisms of PAH.

Names and Identifiers

Pubchem Sid	488183717
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488183717
IUPAC Name	4-amino-N-[2-(diethylamino)ethyl]benzamide;hydrochloride
INCHI	InChI=1S/C13H21N3O.ClH/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17);1H
InChi Key	ABTXGJFUQRCPNH-UHFFFAOYSA-N
Canonical SMILES	CCN(CC)CCNC(=O)C1=CC=C(C=C1)N.Cl
Isomeric SMILES	CCN(CC)CCNC(=O)C1=CC=C(C=C1)N.Cl
RTECS	CV2295000
PubChem CID	66068
Molecular Weight	271.79

Certificates

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7 results found

Lot Number	Certificate Type	Date	Item
I2104272	Certificate of Analysis	Jun 20, 2024	P171174
I2104273	Certificate of Analysis	Jun 12, 2024	P171174
D2415005	Certificate of Analysis	Mar 08, 2024	P171174
B2428212	Certificate of Analysis	Feb 19, 2024	P171174
B2428213	Certificate of Analysis	Feb 19, 2024	P171174
B2428214	Certificate of Analysis	Feb 19, 2024	P171174
H2414027	Certificate of Analysis	Feb 19, 2024	P171174

Sensitivity

Moisture, air and light sensitive

Melt Point(°C)

155-169℃

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
RTECS	CV2295000

References

1. Hasan SS et al.. (2018) Cryo-EM Structures of Eastern Equine Encephalitis Virus Reveal Mechanisms of Virus Disassembly and Antibody Neutralization.. Cell Rep, 25 (11): (3136-3147.e5). [PMID:30540945]
2. Derking R et al.. (2021) Enhancing glycan occupancy of soluble HIV-1 envelope trimers to mimic the native viral spike.. Cell Rep, 35 (108933). [PMID:33826885]
3. Seabright GE et al.. (2020) Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions.. Structure, 28 (8): (897-909.e6). [PMID:32433992]
4. Struwe WB et al.. (2018) Site-Specific Glycosylation of Virion-Derived HIV-1 Env Is Mimicked by a Soluble Trimeric Immunogen.. Cell Rep, 24 (8): (1958-1966.e5). [PMID:30134158]

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Basic Description