Determine the necessary mass, volume, or concentration for preparing a solution.
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SKU | Size | Availability | Price | Qty |
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P425041-1ml | 1ml | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $172.90 |
H1 receptor Selective Inhibitors | Agonists | Antagonists
Synonyms | promethazine | Proazamine | 60-87-7 | Diphergan | Protazine | Promethazin | Prometazin | Vallergine | Dimapp | Fargan | Procit | Promazinamide | Promezathine | Phenargan | Prothazin | Diprazine | Histargan | Phensedyl | Phargan | Tanidil | Thiergan | Isophenergan | Pyrethiazine | Diprozin | Fenetazina | |
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Specifications & Purity | Moligand™, 10mM in DMSO |
Biochemical and Physiological Mechanisms | Promethazine is a potent histamine H1 receptor antagonist. Promethazine is a medication used in the management and treatment of allergic conditions, nausea and vomiting, motion sickness, and sedation. Promethazine exhibits antiparasitic properties. |
Storage Temp | Store at -80°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Product Description | Information Promethazine is a potenthistamine H1 receptorantagonist. Promethazine is a medication used in the management and treatment of allergic conditions, nausea and vomiting, motion sickness, and sedation. Promethazine exhibits antiparasitic properties. Targets histamine H1 receptor |
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IUPAC Name | N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine |
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INCHI | InChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3 |
InChi Key | PWWVAXIEGOYWEE-UHFFFAOYSA-N |
Canonical SMILES | CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C |
Isomeric SMILES | CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C |
PubChem CID | 4927 |
Molecular Weight | 284.42 |
Enter Lot Number to search for COA:
Pictogram(s) | GHS09, GHS07 |
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Signal | Warning |
Hazard Statements | H319:Causes serious eye irritation H302:Harmful if swallowed H410:Very toxic to aquatic life with long lasting effects |
Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P391:Collect spillage. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. |
1. Chen Yanming, Xiao Xinyi, Huang Chaonan, Zhu Jin, Zhou Huiling, Qin Huimin, Bao Yu, Zhuang Tao, Zhang Guisen. (2023) Flupirtine and antihistamines exert synergistic anti-nociceptive effects in mice. PSYCHOPHARMACOLOGY, 240 (4): (881-897). [PMID:36752814] |
2. Boxuan Yao, Ke Zhang, Xiaoyang Liu, Hua Wei, Zihan Li, Jiarui Zhou, Guangfei Yuan, Xin Wang, Shenghong Yang, Jian Liu. (2023) Versatile preparation strategy of negatively charged saccharide-based polymers for selective removal of cationic organic pollutants. APPLIED SURFACE SCIENCE, 616 (156428). [PMID:] |
3. Mingqian Song, Changxin Li, Shijia Wu, Nuo Duan. (2023) Screening of specific aptamers against chlorpromazine and construction of novel ratiometric fluorescent aptasensor based on metal-organic framework. TALANTA, 252 (123850). [PMID:36049339] |
4. Yongtao You, Silan Bai, Yamin Ma, Cheng Liu, Lishi Wang. (2022) A Nanopipette Supported Oil/Water Interface Sensor for the Kinetics Analysis and Determination of Phenothiazine Derivatives. ELECTROCHIMICA ACTA, 423 (140568). [PMID:] |
1. Chen Yanming, Xiao Xinyi, Huang Chaonan, Zhu Jin, Zhou Huiling, Qin Huimin, Bao Yu, Zhuang Tao, Zhang Guisen. (2023) Flupirtine and antihistamines exert synergistic anti-nociceptive effects in mice. PSYCHOPHARMACOLOGY, 240 (4): (881-897). [PMID:36752814] |
2. Boxuan Yao, Ke Zhang, Xiaoyang Liu, Hua Wei, Zihan Li, Jiarui Zhou, Guangfei Yuan, Xin Wang, Shenghong Yang, Jian Liu. (2023) Versatile preparation strategy of negatively charged saccharide-based polymers for selective removal of cationic organic pollutants. APPLIED SURFACE SCIENCE, 616 (156428). [PMID:] |
3. Mingqian Song, Changxin Li, Shijia Wu, Nuo Duan. (2023) Screening of specific aptamers against chlorpromazine and construction of novel ratiometric fluorescent aptasensor based on metal-organic framework. TALANTA, 252 (123850). [PMID:36049339] |
4. Yongtao You, Silan Bai, Yamin Ma, Cheng Liu, Lishi Wang. (2022) A Nanopipette Supported Oil/Water Interface Sensor for the Kinetics Analysis and Determination of Phenothiazine Derivatives. ELECTROCHIMICA ACTA, 423 (140568). [PMID:] |