Prostaglandin J2 - 95%,5 mg/mL in methyl acetate, high purity , CAS No.60203-57-8, Agonist of DP 1 receptor;Agonist of DP 2 receptor

Item Number
P275004
Grouped product items
SKUSizeAvailabilityPrice Qty
P275004-500μg
500μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
P275004-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$563.90
P275004-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,348.90

Endogenous product of inflammation; PGD 2 analog

Basic Description

SynonymsBDBM50594729 | C05957 | BML1-G07 | PGJ2 (Prostaglandin J2) | Prostaglandin J2 Lipid Maps(R) MS Standard | SR-05000002330-3 | 8-epi-15-J2t-IsoP | HMS1989K20 | LMFA03010019 | (5Z,13E,15S)-15-hydroxy-11-oxoprosta-5,9,13-trien-1-oic acid | CHEBI:27485 | GTPL1
Specifications & PurityMoligand™, ≥95%, 5 mg/mL in methyl acetate
Biochemical and Physiological MechanismsEndogenous highly reactive product of inflammation. PGD 2 analog. Potent neurotoxin and activator of PPARα and PPARγ. Able to trigger pro-apoptotic responses in neuronal cells.
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of DP 1 receptor;Agonist of DP 2 receptor
NoteProviding storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

PTGDR Tclin Prostaglandin D2 receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGDR2 Tchem Prostaglandin D2 receptor 2 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
UCHL3 Tchem Ubiquitin carboxyl-terminal hydrolase isozyme L3 (50 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (Z)-7-[(1S,5R)-5-[(E,3S)-3-hydroxyoct-1-enyl]-4-oxocyclopent-2-en-1-yl]hept-5-enoic acid
INCHI InChI=1S/C20H30O4/c1-2-3-6-10-17(21)13-14-18-16(12-15-19(18)22)9-7-4-5-8-11-20(23)24/h4,7,12-18,21H,2-3,5-6,8-11H2,1H3,(H,23,24)/b7-4-,14-13+/t16-,17-,18+/m0/s1
InChi Key UQOQENZZLBSFKO-POPPZSFYSA-N
Canonical SMILES CCCCCC(C=CC1C(C=CC1=O)CC=CCCCC(=O)O)O
Isomeric SMILES CCCCC[C@@H](/C=C/[C@@H]1[C@H](C=CC1=O)C/C=C\CCCC(=O)O)O
PubChem CID 5280884
Molecular Weight 334.45

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
J2429547Certificate of AnalysisOct 17, 2024 P275004
G2424414Certificate of AnalysisJul 02, 2024 P275004
G2424415Certificate of AnalysisJul 02, 2024 P275004
E2329228Certificate of AnalysisMar 20, 2024 P275004
D2311693Certificate of AnalysisMar 27, 2023 P275004

Chemical and Physical Properties

SolubilitySupplied in methyl acetate (5 mg/ml)

Related Documents

Solution Calculators