Proteasome 26S S2/PSMD2 Antibody - Primary antibody, specific to Proteasome 26S S2/PSMD2, Rabbit IgG

    Application:
  • IF/ICC
  • IHC
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Cow,Human
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab123413
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab123413-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab123413-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$189.90
Ab123413-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
Ab123413-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,999.90

pAb; Rabbit anti Human Proteasome 26S S2/PSMD2 Antibody; WB, IHC, IF/ICC; Unconjugated

Basic Description

Product NameProteasome 26S S2/PSMD2 Antibody - Primary antibody, specific to Proteasome 26S S2/PSMD2, Rabbit IgG
Synonyms26S proteasome non-ATPase regulatory subunit 2 antibody | 26S proteasome regulatory subunit RPN1 antibody | 26S proteasome regulatory subunit S2 antibody | 26S proteasome subunit p97 antibody | 55.11 protein antibody | MGC14274 antibody | P97 antibody | P
Specifications & PurityCarrier Free, ExactAb™, Validated, 1.0 mg/mL
Biochemical and Physiological MechanismsComponent of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could imp
Host speciesRabbit
SpecificityProteasome 26S S2/PSMD2
ImmunogenKLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Proteasome 26S S2/PSMD2.
Positive ControlWB: A431, HeLa, Jurkat, HEK293, MCF7 and U-2 OS cell lysates. IHC: Human brain tissue. IF/ICC: HeLa cells.
ConjugationUnconjugated
GradeCarrier Free, ExactAb™, Validated
Product Description

Rabbit anti Human Proteasome 26S S2/PSMD2 Antibody, Polyclonal, could be used for WB, IHC, IF/ICC and so on.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodImmunogen affinity purified
FormLiquid
Concentration1.0 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

PSMD2 Tbio 26S proteasome non-ATPase regulatory subunit 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB1/500-1/1000

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1/500-1/1000

IHC1/50 - 1/100

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1/50 - 1/100

IF/ICC1/50 - 1/200

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1/50 - 1/200

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

References

1. Fan H, Angelo NG, Warren JD, Nathan CF, Lin G.  (2014)  Oxathiazolones Selectively Inhibit the Human Immunoproteasome over the Constitutive Proteasome..  ACS Med Chem Lett,  (4): (405-10).  [PMID:24900849] [10.1021/op500134e]
2. Sharon Gauci,Andreas O Helbig,Monique Slijper,Jeroen Krijgsveld,Albert J R Heck,Shabaz Mohammed.  (2009-05-06)  Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach..  Analytical chemistry,  81  ((11)): (4493-4501).  [PMID:19413330]
3. Long MJC, Lawson AP, Baggio R, Qian Y, Rozhansky L, Fasci D, El Oualid F, Weerapana E, Hedstrom L..  (2019)  Diarylcarbonates are a new class of deubiquitinating enzyme inhibitor..  Bioorg Med Chem Lett,  29  (2): (204-211).  [PMID:30528168] [10.1016/j.bmcl.2018.11.055]
4. Kanayama, H O HO and 7 more authors..  (1992)  Demonstration that a human 26S proteolytic complex consists of a proteasome and multiple associated protein components and hydrolyzes ATP and ubiquitin-ligated proteins by closely linked mechanisms..  European journal of biochemistry,    (1):   [PMID:1317798]
5. Boldin, M P MP, Mett, I L IL and Wallach, D D..  (1995)  A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its 'death domain'..  FEBS letters,    (19):   [PMID:7601280]
6. Tsurumi, C C and 12 more authors..  (1996)  cDNA cloning and functional analysis of the p97 subunit of the 26S proteasome, a polypeptide identical to the type-1 tumor-necrosis-factor-receptor-associated protein-2/55.11..  European journal of biochemistry,    (1):   [PMID:8774743]
7. Dunbar, J D JD, Song, H Y HY, Guo, D D, Wu, L W LW and Donner, D B DB..  (1997)  Two-hybrid cloning of a gene encoding TNF receptor-associated protein 2, a protein that interacts with the intracellular domain of the type 1 TNF receptor: identity with subunit 2 of the 26S protease..  Journal of immunology (Baltimore, Md. : 1950),    (1):   [PMID:9126987]
8. Andersen, Jens S JS and 5 more authors..  (2003)  Proteomic characterization of the human centrosome by protein correlation profiling..  Nature,    (4):   [PMID:14654843]
9. Muzny, Donna M DM and 113 more authors..  (2006)  The DNA sequence, annotation and analysis of human chromosome 3..  Nature,    (27):   [PMID:16641997]
10. Wang, Xiaorong X and 5 more authors..  (2007)  Mass spectrometric characterization of the affinity-purified human 26S proteasome complex..  Biochemistry,    (20):   [PMID:17323924]
11. Yu, Li-Rong LR and 5 more authors..  (2007)  Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra..  Journal of proteome research,      [PMID:17924679]
12. Daub, Henrik H and 9 more authors..  (2008)  Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle..  Molecular cell,    (8):   [PMID:18691976]
13. Mayya, Viveka V and 7 more authors..  (2009)  Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions..  Science signaling,    (18):   [PMID:19690332]
14. Rigbolt, Kristoffer T G KT and 9 more authors..  (2011)  System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation..  Science signaling,    (15):   [PMID:21406692]
15. Sun, Shuangwu S and 7 more authors..  (2017)  Phosphatase UBLCP1 controls proteasome assembly..  Open biology,      [PMID:28539385]

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