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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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Ab123413-10μl | 10μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $59.90 | |
Ab123413-50μl | 50μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $189.90 | |
Ab123413-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $309.90 | |
Ab123413-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,999.90 |
pAb; Rabbit anti Human Proteasome 26S S2/PSMD2 Antibody; WB, IHC, IF/ICC; Unconjugated
Product Name | Proteasome 26S S2/PSMD2 Antibody - Primary antibody, specific to Proteasome 26S S2/PSMD2, Rabbit IgG |
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Synonyms | 26S proteasome non-ATPase regulatory subunit 2 antibody | 26S proteasome regulatory subunit RPN1 antibody | 26S proteasome regulatory subunit S2 antibody | 26S proteasome subunit p97 antibody | 55.11 protein antibody | MGC14274 antibody | P97 antibody | P |
Specifications & Purity | Carrier Free, ExactAb™, Validated, 1.0 mg/mL |
Biochemical and Physiological Mechanisms | Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could imp |
Host species | Rabbit |
Specificity | Proteasome 26S S2/PSMD2 |
Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Proteasome 26S S2/PSMD2. |
Positive Control | WB: A431, HeLa, Jurkat, HEK293, MCF7 and U-2 OS cell lysates. IHC: Human brain tissue. IF/ICC: HeLa cells. |
Conjugation | Unconjugated |
Grade | Carrier Free, ExactAb™, Validated |
Product Description |
Rabbit anti Human Proteasome 26S S2/PSMD2 Antibody, Polyclonal, could be used for WB, IHC, IF/ICC and so on.
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Isotype | Rabbit IgG |
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SDS-PAGE | 150 kDa |
Purification Method | Immunogen affinity purified |
Form | Liquid |
Concentration | 1.0 mg/mL |
Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
Shipped In | Ice chest + Ice pads |
Stability And Storage | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Application | Dilution info |
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WB | 1/500-1/1000"> 1/500-1/1000 |
IHC | 1/50 - 1/100 "> 1/50 - 1/100 |
IF/ICC | 1/50 - 1/200 "> 1/50 - 1/200 |
Enter Lot Number to search for COA:
1. Fan H, Angelo NG, Warren JD, Nathan CF, Lin G. (2014) Oxathiazolones Selectively Inhibit the Human Immunoproteasome over the Constitutive Proteasome.. ACS Med Chem Lett, 5 (4): (405-10). [PMID:24900849] [10.1021/op500134e] |
2. Sharon Gauci,Andreas O Helbig,Monique Slijper,Jeroen Krijgsveld,Albert J R Heck,Shabaz Mohammed. (2009-05-06) Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.. Analytical chemistry, 81 ((11)): (4493-4501). [PMID:19413330] |
3. Long MJC, Lawson AP, Baggio R, Qian Y, Rozhansky L, Fasci D, El Oualid F, Weerapana E, Hedstrom L.. (2019) Diarylcarbonates are a new class of deubiquitinating enzyme inhibitor.. Bioorg Med Chem Lett, 29 (2): (204-211). [PMID:30528168] [10.1016/j.bmcl.2018.11.055] |
4. Kanayama, H O HO and 7 more authors.. (1992) Demonstration that a human 26S proteolytic complex consists of a proteasome and multiple associated protein components and hydrolyzes ATP and ubiquitin-ligated proteins by closely linked mechanisms.. European journal of biochemistry, (1): [PMID:1317798] |
5. Boldin, M P MP, Mett, I L IL and Wallach, D D.. (1995) A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its 'death domain'.. FEBS letters, (19): [PMID:7601280] |
6. Tsurumi, C C and 12 more authors.. (1996) cDNA cloning and functional analysis of the p97 subunit of the 26S proteasome, a polypeptide identical to the type-1 tumor-necrosis-factor-receptor-associated protein-2/55.11.. European journal of biochemistry, (1): [PMID:8774743] |
7. Dunbar, J D JD, Song, H Y HY, Guo, D D, Wu, L W LW and Donner, D B DB.. (1997) Two-hybrid cloning of a gene encoding TNF receptor-associated protein 2, a protein that interacts with the intracellular domain of the type 1 TNF receptor: identity with subunit 2 of the 26S protease.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:9126987] |
8. Andersen, Jens S JS and 5 more authors.. (2003) Proteomic characterization of the human centrosome by protein correlation profiling.. Nature, (4): [PMID:14654843] |
9. Muzny, Donna M DM and 113 more authors.. (2006) The DNA sequence, annotation and analysis of human chromosome 3.. Nature, (27): [PMID:16641997] |
10. Wang, Xiaorong X and 5 more authors.. (2007) Mass spectrometric characterization of the affinity-purified human 26S proteasome complex.. Biochemistry, (20): [PMID:17323924] |
11. Yu, Li-Rong LR and 5 more authors.. (2007) Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.. Journal of proteome research, [PMID:17924679] |
12. Daub, Henrik H and 9 more authors.. (2008) Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.. Molecular cell, (8): [PMID:18691976] |
13. Mayya, Viveka V and 7 more authors.. (2009) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.. Science signaling, (18): [PMID:19690332] |
14. Rigbolt, Kristoffer T G KT and 9 more authors.. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.. Science signaling, (15): [PMID:21406692] |
15. Sun, Shuangwu S and 7 more authors.. (2017) Phosphatase UBLCP1 controls proteasome assembly.. Open biology, [PMID:28539385] |