Protodioscin - from Dioscorea spp., ≥98% (HPLC), high purity , CAS No.55056-80-9

  • ≥98%(HPLC)
  • from Dioscorea spp.
Item Number
P477632
Grouped product items
SKUSizeAvailabilityPrice Qty
P477632-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$187.90
P477632-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$667.90

Basic Description

SynonymsProtodioscin | 55056-80-9 | Furostanol I | UNII-D0LC3PH24P | D0LC3PH24P | PROTODIOSCINE | CHEBI:8588 | Furostane base-2H + O-Hex, O-Hex-dHex-dHex | MFCD03427682 | (3beta,22R,25R)-26-(beta-D-glucopyranosyloxy)-22-hydroxyfurost-5-en-3-yl alpha-L-rhamnopyranosyl-(1->2)-[alpha
Specifications & Purity≥98%(HPLC), from Dioscorea spp.
Biochemical and Physiological MechanismsProtodioscin shows a notable inhibitory effect on digestive enzymes such as α-amylase and pancreatic lipase. It is posited to increase the levels of testosterone, luteinizing hormone, dehydroepiandrosterone, dihydrotestosterone, and dehydroepiandrosterone
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

Protodioscin is a steroidal saponin found in a variety of plant species. It consists of aglycone and glycone moieties and occurs as an active ingredient of the herbal aphrodisiacTribulus terrestrisused in traditional Chinese and Indian medicine.Protodioscin has been used to study the inhibitory effect of fenugreek and quinoa extracts on the activity of α-amylase and pancreatic lipase underin vitrotraditional conditions. It has also been used as a standard in the study to carry out the structural characterization of the steroidal saponins extracted fromSmilax trinervula.

Associated Targets(Human)

HUVEC (11049 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK-293T (167025 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2S,3R,4R,5R,6S)-2-[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[[(1S,2S,4S,6R,7S,8R,9S,12S,13R,16S)-6-hydroxy-7,9,13-trimethyl-6-[(3R)-3-methyl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybutyl]-5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-en-16-yl]oxy]-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol
INCHI InChI=1S/C51H84O22/c1-20(19-65-45-39(60)38(59)35(56)30(17-52)69-45)9-14-51(64)21(2)32-29(73-51)16-28-26-8-7-24-15-25(10-12-49(24,5)27(26)11-13-50(28,32)6)68-48-44(72-47-41(62)37(58)34(55)23(4)67-47)42(63)43(31(18-53)70-48)71-46-40(61)36(57)33(54)22(3)66-46/h7,20-23,25-48,52-64H,8-19H2,1-6H3/t20-,21+,22+,23+,25+,26-,27+,28+,29+,30-,31-,32+,33+,34+,35-,36-,37-,38+,39-,40-,41-,42+,43-,44-,45-,46+,47+,48-,49+,50+,51-/m1/s1
InChi Key LVTJOONKWUXEFR-UEZXSUPNSA-N
Canonical SMILES CC1C2C(CC3C2(CCC4C3CC=C5C4(CCC(C5)OC6C(C(C(C(O6)CO)OC7C(C(C(C(O7)C)O)O)O)O)OC8C(C(C(C(O8)C)O)O)O)C)C)OC1(CCC(C)COC9C(C(C(C(O9)CO)O)O)O)O
Isomeric SMILES C[C@H]1[C@H]2[C@H](C[C@@H]3[C@@]2(CC[C@H]4[C@H]3CC=C5[C@@]4(CC[C@@H](C5)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O[C@H]7[C@@H]([C@@H]([C@H]([C@@H](O7)C)O)O)O)O)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)C)C)O[C@@]1(CC[C@@H](C)CO[C@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)O
PubChem CID 441891
Molecular Weight 1049.21

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References

1. Kalamegam Gauthaman, Adaikan P Ganesan, R N V Prasad,.  (2003-06-14)  Sexual effects of puncturevine (Tribulus terrestris) extract (protodioscin): an evaluation using a rat model..  Journal of alternative and complementary medicine (New York, N.Y.),  ((2)): ( 257-265 ).  [PMID:12804079]

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