PSB-1584 , CAS No.P612988, Agonist of GPR84

Item Number
P612988
Grouped product items
SKUSizeAvailabilityPrice Qty
P612988-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$922.90
P612988-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,226.90
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GPR84 Agonist

Basic Description

Synonyms6-hexylaminouracil;compound 20;PSB1584
Specifications & PurityMoligand™
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of GPR84

Associated Targets(Human)

GPR84 Tchem G-protein coupled receptor 84 (3 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GPR84 Tchem G-protein coupled receptor 84 (1284 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

topB DNA topoisomerase III (145 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 6-(hexylamino)-1H-pyrimidine-2,4-dione
INCHI InChI=1S/C10H17N3O2/c1-2-3-4-5-6-11-8-7-9(14)13-10(15)12-8/h7H,2-6H2,1H3,(H3,11,12,13,14,15)
InChi Key SDXQSUJXSHUIBQ-UHFFFAOYSA-N
Canonical SMILES CCCCCCNc1cc(=O)[nH]c(=O)[nH]1
Isomeric SMILES CCCCCCNC1=CC(=O)NC(=O)N1
PubChem CID 44349321

Certificates

Certificate of Analysis(COA)

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Related Documents

References

1. Pillaiyar T, Köse M, Namasivayam V, Sylvester K, Borges G, Thimm D, von Kügelgen I, Müller CE.  (2018)  6-(Ar)Alkylamino-Substituted Uracil Derivatives: Lipid Mimetics with Potent Activity at the Orphan G Protein-Coupled Receptor 84 (GPR84)..  ACS Omega,  (3): (3365-3383).  [PMID:30023867]
2. Köse M, Pillaiyar T, Namasivayam V, De Filippo E, Sylvester K, Ulven T, von Kügelgen I, Müller CE.  (2020)  An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights..  J Med Chem,  63  (5): (2391-2410).  [PMID:31721581]

Solution Calculators