PTP1B-IN-2 (MDK3465, Ptp1B-In-2, Compound P6) is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 50 nM. PTP1B-IN-2 enhances insulin-mediated insulin receptor β (IRβ) phosphorylation and insulin-stimulated glucose upta
Storage Temp
Store at -80°C
Shipped In
Ice chest + Ice pads
Product Description
Information
PTP1B-IN-2 PTP1B-IN-2 (MDK3465, Ptp1B-In-2, Compound P6) is a potent and selective protein tyrosine phosphatase-1B (PTP1B) inhibitor with IC50 of 50 nM. PTP1B-IN-2 enhances insulin-mediated insulin receptor β (IRβ) phosphorylation and insulin-stimulated glucose uptake.
Targets
PTP1B (Cell-free assay) 50 nM
Product Properties
ALogP
4.846
Rotatable Bond
16
Associated Targets(Human)
PTPN2TchemTyrosine-protein phosphatase non-receptor type 2 (1 Activities)
