Purvalanol A - ≥98%, high purity , CAS No.212844-53-6, Inhibitor of cyclin dependent kinase 2;Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 5

Item Number

P275411

• Synonyms: A846523 | BDBM27216 | Purvalanol A, >=98% (HPLC), powder | 1-BUTANOL, 2-((6-((3-CHLOROPHENYL)AMINO)-9-(1-METHYLETHYL)-9H-PURIN-2-YL)AMINO)-3-METHYL-, (2R)- | BCBcMAP01_000180 | (R)-2-((6-((3-Chlorophenyl)amino)-9-isopropyl-9H-purin-2-yl)amino)-3-methylbut
• Specifications & Purity: Moligand™, ≥98%
• Biochemical and Physiological Mechanisms: Potent CDK inhibitor (IC 50 = 100 nM for CDK2/cyclin A). Also inhibits other kinases in the low micromolar range, including DYRK1A and RSK1 (IC 50 values are 0.3 and 1.49 μM, respectively). Purvalanol A is found to inhibit ABCG2 (ATP-binding cassette G2)
• Storage Temp: Store at -20°C,Desiccated
• Shipped In: Ice chest + Ice pads
• Grade: Moligand™
• Action Type: INHIBITOR
• Mechanism of action: Inhibitor of cyclin dependent kinase 2;Inhibitor of cyclin dependent kinase 4;Inhibitor of cyclin dependent kinase 5
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Store under desiccating conditions. The product can be stored for up to 12 months.