Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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P101874-1g | 1g | In stock | $82.90 | |
P101874-5g | 5g | In stock | $373.90 | |
P101874-10g | 10g | In stock | $672.90 | |
P101874-25g | 25g | In stock | $1,512.90 | |
P101874-100g | 100g | In stock | $5,445.90 | |
P101874-500g | 500g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $24,505.90 |
Synonyms | PLP | Vitazechs | FT-0631236 | P5P | P-5'-P | Pyromijin | 3-Hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde 5-phosphate | CCG-266929 | EX-A980 | MC-1 | Pyridoxal 5/'-phosphate (hydrate) | SGCUT00188 | VITAMIN B6 (PYRIDOXAL 5-PHOSPHATE) | 3-hydroxy-2- |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Pyridoxal 5′-phosphate (PLP) aids in carbohydrate and fat metabolism by serving as a cofactor. It is majorly responsible for catalyzing the enzymatic reactions involved in sphingolipid synthesis and neurotransmitter (dopamine and serotonin) synthesis. PLP |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Grade | Moligand™ |
Product Description | Pyridoxal 5′-phosphate (PLP) is synthesized in a multiple-step process. The two pathways inlcude pyridoxal phosphate biosynthetic protein (PdxA)- pyridoxine-5′-phosphate synthase (PdxJ) pathway and the pyridoxal 5′-phosphate synthase subunit PDX1/PDX2 pathway. It is the active form of pyridoxine.
Pyridoxal 5′-phosphate hydrate has also been used:
• as a reference standard to quantify vitamin B6 in feed and digesta samples using high performance liquid chromatography (HPLC)
• in D-amino acid transaminase reaction(10)
• as a cofactor for L-glutamic acid decarboxylase |
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IUPAC Name | (4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate |
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INCHI | InChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14) |
InChi Key | NGVDGCNFYWLIFO-UHFFFAOYSA-N |
Canonical SMILES | CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O |
Isomeric SMILES | CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O |
PubChem CID | 1051 |
Molecular Weight | 247.14 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
E2209055 | Certificate of Analysis | Feb 23, 2024 | P101874 |
E2209052 | Certificate of Analysis | Feb 23, 2024 | P101874 |
E2209054 | Certificate of Analysis | Feb 23, 2024 | P101874 |
I2126311 | Certificate of Analysis | Jul 10, 2023 | P101874 |
I2126310 | Certificate of Analysis | Jul 10, 2023 | P101874 |
B2327513 | Certificate of Analysis | Mar 01, 2023 | P101874 |
B2327667 | Certificate of Analysis | Mar 01, 2023 | P101874 |
B2327530 | Certificate of Analysis | Mar 01, 2023 | P101874 |
F2428046 | Certificate of Analysis | Jan 12, 2023 | P101874 |
G2305718 | Certificate of Analysis | Jan 12, 2023 | P101874 |
G2305812 | Certificate of Analysis | Jan 12, 2023 | P101874 |
G2305813 | Certificate of Analysis | Jan 12, 2023 | P101874 |
G2305814 | Certificate of Analysis | Jan 12, 2023 | P101874 |
G2305815 | Certificate of Analysis | Jan 12, 2023 | P101874 |
G2305816 | Certificate of Analysis | Jan 12, 2023 | P101874 |
G2305817 | Certificate of Analysis | Jan 12, 2023 | P101874 |
G2305818 | Certificate of Analysis | Jan 12, 2023 | P101874 |
G2305819 | Certificate of Analysis | Jan 12, 2023 | P101874 |
G2305820 | Certificate of Analysis | Jan 12, 2023 | P101874 |
G2305821 | Certificate of Analysis | Jan 12, 2023 | P101874 |
G2305822 | Certificate of Analysis | Jan 12, 2023 | P101874 |
A2303251 | Certificate of Analysis | Nov 23, 2022 | P101874 |
Solubility | Soluble in oxygen-free H2O. Insoluble in most organic solvents. |
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Sensitivity | Moisture sensitive |
Melt Point(°C) | 140-143°C |
Starting at $43.90
Starting at $17.90
Starting at $69.90
Starting at $69.90
Starting at $69.90
Starting at $62.90
1. Zixin Teng, Xuewei Pan, Yunran Liu, Jiajia You, Hengwei Zhang, Zhenqiang Zhao, Zhina Qiao, Zhiming Rao. (2024) Engineering serine hydroxymethyltransferases for efficient synthesis of L-serine in Escherichia coli. BIORESOURCE TECHNOLOGY, 393 (22): (130153). [PMID:38052329] [10.1016/j.biortech.2023.130153] |
2. Nan Jiang, Xiaotong Du, Liangyu Zheng. (2023) Highly efficient synthesis of chiral lactams by using a ω-transaminase from Bacillus megaterium and its mutant enzymes. Molecular Catalysis, 547 (113364). [PMID:] [10.1016/j.mcat.2023.113364] |
3. Hongpeng Wang, Mercy Vimbai Masuku, Yachen Tao, Jiayao Yang, Yi Kuang, Changjiang Lyu, Jun Huang, Shengxiang Yang. (2023) Improved Stability and Catalytic Efficiency of ω-Transaminase in Aqueous Mixture of Deep Eutectic Solvents. MOLECULES, 28 (9): (3895). [PMID:37175305] [10.3390/molecules28093895] |
4. Juanjuan Ding, Wenyan Ba, Shengping You, Wei Qi, Rongxin Su. (2023) Development of an oil-sealed anaerobic fermentation process for high production of γ-aminobutyric acid with Lactobacillus brevis isolated by directional colorimetric screening. BIOCHEMICAL ENGINEERING JOURNAL, 194 (108893). [PMID:] [10.1016/j.bej.2023.108893] |
5. Xiao-Ling Tang, Ning Li, Yan-Lai Liu, Jing-Peng Li, Kai-Xuan Zhao, Zhi-Qiang Liu, Yu-Guo Zheng. (2023) Engineering O-Succinyl-L-Homoserine Mercaptotransferase for Efficient L-Methionine Biosynthesis by Fermentation-Enzymatic Coupling Route. ADVANCED SYNTHESIS & CATALYSIS, 365 (7): (1048-1057). [PMID:] [10.1002/adsc.202300030] |
6. Xingchang Cha, Juanjuan Ding, Wenyan Ba, Shengping You, Wei Qi, Rongxin Su. (2023) High Production of γ-Aminobutyric Acid by Activating the xyl Operon of Lactobacillus brevis. ACS Omega, 8 (8): (8101–8109). [PMID:36873027] [10.1021/acsomega.2c08272] |
7. Shiyi Wang, Yiwen Zhao, Shufen Mao, Jiang Zhu, Yangyang Zhan, Dongbo Cai, Xin Ma, Dong Wang, Shouwen Chen. (2023) Enhancing the activity of disulfide-bond-containing proteins via promoting disulfide bond formation in Bacillus licheniformis. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 233 (123468). [PMID:36731702] [10.1016/j.ijbiomac.2023.123468] |
8. Lian Xu, Dan Nie, Bing-Mei Su, Xin-Qi Xu, Juan Lin. (2023) A chemoenzymatic strategy for the efficient synthesis of amphenicol antibiotic chloramphenicol mediated by an engineered L-threonine transaldolase with high activity and stereoselectivity. Catalysis Science & Technology, 13 (3): (684-693). [PMID:] [10.1039/D2CY01670B] |
9. Sai Fang, Haoran Yu, Lanxin Xiao, Zhe Wang, Yixuan Lei, Gang Xu, Lirong Yang, Wenlong Zheng, Jianping Wu. (2022) Counteracting the Activity-Diastereoselectivity Trade-Off of l-Threonine Aldolase by Regulating the Proton Transfer Microenvironment. ADVANCED SYNTHESIS & CATALYSIS, 364 (24): (4363-4370). [PMID:] [10.1002/adsc.202201006] |
10. Kai Yuan, Kai Huang, Yiqi Yang, Yixuan Lin, Yihao Liu, Fupeng Li, Yakun Liang, Haishuang Chang, Yuhui Chen, Tingting Tang, Shengbing Yang. (2022) Multi-roles of nanoscale bismuth metal-organic frameworks: Infectious photoacoustic probe and inhibitor of antibiotics tolerant bacteria via targeting endogenous H2S. Nano Today, 47 (101683). [PMID:] [10.1016/j.nantod.2022.101683] |
11. Guozeng Wang, Zhihao Jiang, Qing Xiao, Chang Jiang, Xian'ai Shi. (2022) Visible spectrophotometric assay for characterization of ω-transaminases. ANALYTICAL BIOCHEMISTRY, 658 (114933). [PMID:36208685] [10.1016/j.ab.2022.114933] |
12. Deng Hao-Hua, Yang Hui-Jing, Huang Kai-Yuan, Zheng Yi-Jing, Xu Ying-Ying, Peng Hua-Ping, Liu Yin-Huan, Chen Wei, Hong Guo-Lin. (2022) Antenna effect of pyridoxal phosphate on the fluorescence of mitoxantrone-silicon nanoparticles and its application in alkaline phosphatase assay. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (17): (4877-4884). [PMID:35576012] [10.1007/s00216-022-04110-7] |
13. Li-Chao Wang, Lian Xu, Bing-Mei Su, Xin-Qi Xu, Juan Lin. (2022) An Effective Chemo-Enzymatic method with An Evolved L-Threonine Aldolase for Preparing L-threo-4-Methylsulfonylphenylserine Ethyl Ester of High Optical Purity. Molecular Catalysis, 525 (112355). [PMID:] [10.1016/j.mcat.2022.112355] |
14. Wang Dong-En, You Shangqi, Huo Wenjing, Han Xiang, Xu Huiyun. (2022) Colorimetric detection of alkaline phosphatase activity based on pyridoxal phosphate–induced chromatic switch of polydiacetylene nano-liposomes. MICROCHIMICA ACTA, 189 (2): (1-12). [PMID:35067757] [10.1007/s00604-022-05175-y] |
15. Hang-Qin Zhu, Wen-Ye Hu, Xiao-Ling Tang, Ren-Chao Zheng, Yu-Guo Zheng. (2022) High-throughput assay of tyrosine phenol-lyase activity using a cascade of enzymatic reactions. ANALYTICAL BIOCHEMISTRY, 640 (114547). [PMID:35026146] [10.1016/j.ab.2022.114547] |
16. Jiahao Yao, Zhuang Li, Xiuling Ji, Yaju Xue, Baozeng Ren, Hai Zhao, Yuhong Huang. (2021) Novel enzyme-metal-organic framework composite for efficient cadaverine production. BIOCHEMICAL ENGINEERING JOURNAL, 176 (108222). [PMID:] [10.1016/j.bej.2021.108222] |
17. Hu Jiawei, Li Wei, Liu Zhan, Zhang Guolin, Luo Yinggang. (2021) Molecular cloning and functional characterization of tyrosine decarboxylases from galanthamine-producing Lycoris radiata. ACTA PHYSIOLOGIAE PLANTARUM, 43 (6): (1-12). [PMID:] [10.1007/s11738-021-03258-6] |
18. Zhu Wen-Yuan, Niu Kun, Liu Peng, Fan Yu-Hang, Liu Zhi-Qiang, Zheng Yu-Guo. (2021) Identification and Characterization of an O-Succinyl-L-Homoserine Sulfhydrylase From Thioalkalivibrio sulfidiphilus. Frontiers in Chemistry, 9 [PMID:33937207] [10.3389/fchem.2021.672414] |
19. Lichao Wang, Lian Xu, Bingmei Su, Wei Lin, Xinqi Xu, Juan Lin. (2021) Improving the Cβ Stereoselectivity of l-Threonine Aldolase for the Synthesis of l-threo-4-Methylsulfonylphenylserine by Modulating the Substrate-Binding Pocket To Control the Orientation of the Substrate Entrance. CHEMISTRY-A EUROPEAN JOURNAL, 27 (37): (9654-9660). [PMID:33843095] [10.1002/chem.202100752] |
20. Jingbai Wen, Jie Bao. (2021) Improved fermentative γ-aminobutyric acid production by secretory expression of glutamate decarboxylase by Corynebacterium glutamicum. JOURNAL OF BIOTECHNOLOGY, 331 (19). [PMID:33711360] [10.1016/j.jbiotec.2021.03.003] |
21. Hongjie Hui, Yajun Bai, Tai-Ping Fan, Xiaohui Zheng, Yujie Cai. (2020) Biosynthesis of Putrescine from L-arginine Using Engineered Escherichia coli Whole Cells. Catalysts, 10 (9): (947). [PMID:] [10.3390/catal10090947] |
22. Li-Chao Wang, Lian Xu, Xin-Qi Xu, Bing-Mei Su, Juan Lin. (2020) An L-threonine aldolase for asymmetric synthesis of β-hydroxy-α-amino acids. CHEMICAL ENGINEERING SCIENCE, 226 (115812). [PMID:] [10.1016/j.ces.2020.115812] |
23. Zhu Hang-Qin, Tang Xiao-Ling, Zheng Ren-Chao, Zheng Yu-Guo. (2020) Purification and Biochemical Characterization of a Tyrosine Phenol-lyase from Morganella morganii. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 192 (1): (71-84). [PMID:32236865] [10.1007/s12010-020-03301-1] |
24. Hao-Hua Deng, Kai-Yuan Huang, Quan-Hui Fang, Ya-Ping Lv, Shao-Bin He, Hua-Ping Peng, Xing-Hua Xia, Wei Chen. (2020) Schiff base and Lewis acid-base interaction-regulated aggregation/dispersion of gold nanoparticles for colorimetric recognition of rare-earth Sc3+ ions. SENSORS AND ACTUATORS B-CHEMICAL, 311 (127925). [PMID:] [10.1016/j.snb.2020.127925] |
25. Hao-Hua Deng, Kai-Yuan Huang, Shao-Bin He, Li-Ping Xue, Hua-Ping Peng, Dai-Jun Zha, Wei-Ming Sun, Xing-Hua Xia, Wei Chen. (2020) Rational Design of High-Performance Donor–Linker–Acceptor Hybrids Using a Schiff Base for Enabling Photoinduced Electron Transfer. ANALYTICAL CHEMISTRY, 92 (2): (2019–2026). [PMID:31854983] [10.1021/acs.analchem.9b04434] |
26. Lian Xu, Li-Chao Wang, Xin-Qi Xu, Juan Lin. (2019) Characteristics of L-threonine transaldolase for asymmetric synthesis of β-hydroxy-α-amino acids. Catalysis Science & Technology, 9 (21): (5943-5952). [PMID:] [10.1039/C9CY01608B] |
27. Xiao-Ling Tang, Nan-Nan Zhang, Guo-Yan Ye, Yu-Guo Zheng. (2019) Efficient biosynthesis of (R)-3-amino-1-butanol by a novel (R)-selective transaminase from Actinobacteria sp.. JOURNAL OF BIOTECHNOLOGY, 295 (49). [PMID:30853639] [10.1016/j.jbiotec.2019.02.008] |
28. Xiao-Ling Tang, Hui Suo, Ren-Chao Zheng, Yu-Guo Zheng. (2018) An efficient colorimetric high-throughput screening method for synthetic activity of tyrosine phenol-lyase. ANALYTICAL BIOCHEMISTRY, 560 (7). [PMID:30176231] [10.1016/j.ab.2018.08.026] |
29. Zhang Zhi-Jun, Cai Rui-Feng, Xu Jian-He. (2018) Characterization of a new nitrilase from Hoeflea phototrophica DFL-43 for a two-step one-pot synthesis of (S)-β-amino acids. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 102 (14): (6047-6056). [PMID:29744634] [10.1007/s00253-018-9057-7] |
30. Qian Wang, Xiao-Mei He, Xi Chen, Gang-Tian Zhu, Ren-Qi Wang, Yu-Qi Feng. (2017) Pyridoxal 5′-phosphate mediated preparation of immobilized metal affinity material for highly selective and sensitive enrichment of phosphopeptides. JOURNAL OF CHROMATOGRAPHY A, 1499 (30). [PMID:28390667] [10.1016/j.chroma.2017.03.085] |
31. Wu Hua-Lei, Zhang Jian-Dong, Zhang Chao-Feng, Fan Xiao-Jun, Chang Hong-Hong, Wei Wen-Long. (2017) Characterization of Four New Distinct ω-Transaminases from Pseudomonas putida NBRC 14164 for Kinetic Resolution of Racemic Amines and Amino Alcohols. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 181 (3): (972-985). [PMID:27714638] [10.1007/s12010-016-2263-9] |
32. Ailin Xiao, Jing Li, Tianjian Liu, Zhuxi Liu, Chuanfei Wei, Xiaomeng Xu, Qin Li, Jingxin Li. (2016) l-Cysteine enhances nutrient absorption via a cystathionine-β-synthase-derived H2S pathway in rodent jejunum. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 43 (5): (562-568). [PMID:26901099] [10.1111/1440-1681.12562] |
33. S. Tang, D. Huang, N. An, D. Chen, D. Zhao. (2016) A novel pathway for the production of H2S by DAO in rat jejunum. NEUROGASTROENTEROLOGY AND MOTILITY, 28 (5): (687-692). [PMID:26813142] [10.1111/nmo.12765] |
34. Miao Chen, Liya Rong, Xiaoqing Chen. (2015) A simple and sensitive detection of glutamic-pyruvic transaminase activity based on fluorescence quenching of bovine serum albumin. RSC Advances, 5 (125): (103557-103562). [PMID:] [10.1039/C5RA24162F] |
35. Ailin Xiao,Hongjuan Wang,Xin Lu,Jianchun Zhu,Di Huang,Tonghui Xu,Jianqiang Guo,Chuanyong Liu,Jingxin Li. (2015-11-05) H2S, a novel gasotransmitter, involves in gastric accommodation.. Scientific reports, 5 (16086-16086). [PMID:26531221] |
1. Zixin Teng, Xuewei Pan, Yunran Liu, Jiajia You, Hengwei Zhang, Zhenqiang Zhao, Zhina Qiao, Zhiming Rao. (2024) Engineering serine hydroxymethyltransferases for efficient synthesis of L-serine in Escherichia coli. BIORESOURCE TECHNOLOGY, 393 (22): (130153). [PMID:38052329] [10.1016/j.biortech.2023.130153] |
2. Nan Jiang, Xiaotong Du, Liangyu Zheng. (2023) Highly efficient synthesis of chiral lactams by using a ω-transaminase from Bacillus megaterium and its mutant enzymes. Molecular Catalysis, 547 (113364). [PMID:] [10.1016/j.mcat.2023.113364] |
3. Hongpeng Wang, Mercy Vimbai Masuku, Yachen Tao, Jiayao Yang, Yi Kuang, Changjiang Lyu, Jun Huang, Shengxiang Yang. (2023) Improved Stability and Catalytic Efficiency of ω-Transaminase in Aqueous Mixture of Deep Eutectic Solvents. MOLECULES, 28 (9): (3895). [PMID:37175305] [10.3390/molecules28093895] |
4. Juanjuan Ding, Wenyan Ba, Shengping You, Wei Qi, Rongxin Su. (2023) Development of an oil-sealed anaerobic fermentation process for high production of γ-aminobutyric acid with Lactobacillus brevis isolated by directional colorimetric screening. BIOCHEMICAL ENGINEERING JOURNAL, 194 (108893). [PMID:] [10.1016/j.bej.2023.108893] |
5. Xiao-Ling Tang, Ning Li, Yan-Lai Liu, Jing-Peng Li, Kai-Xuan Zhao, Zhi-Qiang Liu, Yu-Guo Zheng. (2023) Engineering O-Succinyl-L-Homoserine Mercaptotransferase for Efficient L-Methionine Biosynthesis by Fermentation-Enzymatic Coupling Route. ADVANCED SYNTHESIS & CATALYSIS, 365 (7): (1048-1057). [PMID:] [10.1002/adsc.202300030] |
6. Xingchang Cha, Juanjuan Ding, Wenyan Ba, Shengping You, Wei Qi, Rongxin Su. (2023) High Production of γ-Aminobutyric Acid by Activating the xyl Operon of Lactobacillus brevis. ACS Omega, 8 (8): (8101–8109). [PMID:36873027] [10.1021/acsomega.2c08272] |
7. Shiyi Wang, Yiwen Zhao, Shufen Mao, Jiang Zhu, Yangyang Zhan, Dongbo Cai, Xin Ma, Dong Wang, Shouwen Chen. (2023) Enhancing the activity of disulfide-bond-containing proteins via promoting disulfide bond formation in Bacillus licheniformis. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 233 (123468). [PMID:36731702] [10.1016/j.ijbiomac.2023.123468] |
8. Lian Xu, Dan Nie, Bing-Mei Su, Xin-Qi Xu, Juan Lin. (2023) A chemoenzymatic strategy for the efficient synthesis of amphenicol antibiotic chloramphenicol mediated by an engineered L-threonine transaldolase with high activity and stereoselectivity. Catalysis Science & Technology, 13 (3): (684-693). [PMID:] [10.1039/D2CY01670B] |
9. Sai Fang, Haoran Yu, Lanxin Xiao, Zhe Wang, Yixuan Lei, Gang Xu, Lirong Yang, Wenlong Zheng, Jianping Wu. (2022) Counteracting the Activity-Diastereoselectivity Trade-Off of l-Threonine Aldolase by Regulating the Proton Transfer Microenvironment. ADVANCED SYNTHESIS & CATALYSIS, 364 (24): (4363-4370). [PMID:] [10.1002/adsc.202201006] |
10. Kai Yuan, Kai Huang, Yiqi Yang, Yixuan Lin, Yihao Liu, Fupeng Li, Yakun Liang, Haishuang Chang, Yuhui Chen, Tingting Tang, Shengbing Yang. (2022) Multi-roles of nanoscale bismuth metal-organic frameworks: Infectious photoacoustic probe and inhibitor of antibiotics tolerant bacteria via targeting endogenous H2S. Nano Today, 47 (101683). [PMID:] [10.1016/j.nantod.2022.101683] |
11. Guozeng Wang, Zhihao Jiang, Qing Xiao, Chang Jiang, Xian'ai Shi. (2022) Visible spectrophotometric assay for characterization of ω-transaminases. ANALYTICAL BIOCHEMISTRY, 658 (114933). [PMID:36208685] [10.1016/j.ab.2022.114933] |
12. Deng Hao-Hua, Yang Hui-Jing, Huang Kai-Yuan, Zheng Yi-Jing, Xu Ying-Ying, Peng Hua-Ping, Liu Yin-Huan, Chen Wei, Hong Guo-Lin. (2022) Antenna effect of pyridoxal phosphate on the fluorescence of mitoxantrone-silicon nanoparticles and its application in alkaline phosphatase assay. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (17): (4877-4884). [PMID:35576012] [10.1007/s00216-022-04110-7] |
13. Li-Chao Wang, Lian Xu, Bing-Mei Su, Xin-Qi Xu, Juan Lin. (2022) An Effective Chemo-Enzymatic method with An Evolved L-Threonine Aldolase for Preparing L-threo-4-Methylsulfonylphenylserine Ethyl Ester of High Optical Purity. Molecular Catalysis, 525 (112355). [PMID:] [10.1016/j.mcat.2022.112355] |
14. Wang Dong-En, You Shangqi, Huo Wenjing, Han Xiang, Xu Huiyun. (2022) Colorimetric detection of alkaline phosphatase activity based on pyridoxal phosphate–induced chromatic switch of polydiacetylene nano-liposomes. MICROCHIMICA ACTA, 189 (2): (1-12). [PMID:35067757] [10.1007/s00604-022-05175-y] |
15. Hang-Qin Zhu, Wen-Ye Hu, Xiao-Ling Tang, Ren-Chao Zheng, Yu-Guo Zheng. (2022) High-throughput assay of tyrosine phenol-lyase activity using a cascade of enzymatic reactions. ANALYTICAL BIOCHEMISTRY, 640 (114547). [PMID:35026146] [10.1016/j.ab.2022.114547] |
16. Jiahao Yao, Zhuang Li, Xiuling Ji, Yaju Xue, Baozeng Ren, Hai Zhao, Yuhong Huang. (2021) Novel enzyme-metal-organic framework composite for efficient cadaverine production. BIOCHEMICAL ENGINEERING JOURNAL, 176 (108222). [PMID:] [10.1016/j.bej.2021.108222] |
17. Hu Jiawei, Li Wei, Liu Zhan, Zhang Guolin, Luo Yinggang. (2021) Molecular cloning and functional characterization of tyrosine decarboxylases from galanthamine-producing Lycoris radiata. ACTA PHYSIOLOGIAE PLANTARUM, 43 (6): (1-12). [PMID:] [10.1007/s11738-021-03258-6] |
18. Zhu Wen-Yuan, Niu Kun, Liu Peng, Fan Yu-Hang, Liu Zhi-Qiang, Zheng Yu-Guo. (2021) Identification and Characterization of an O-Succinyl-L-Homoserine Sulfhydrylase From Thioalkalivibrio sulfidiphilus. Frontiers in Chemistry, 9 [PMID:33937207] [10.3389/fchem.2021.672414] |
19. Lichao Wang, Lian Xu, Bingmei Su, Wei Lin, Xinqi Xu, Juan Lin. (2021) Improving the Cβ Stereoselectivity of l-Threonine Aldolase for the Synthesis of l-threo-4-Methylsulfonylphenylserine by Modulating the Substrate-Binding Pocket To Control the Orientation of the Substrate Entrance. CHEMISTRY-A EUROPEAN JOURNAL, 27 (37): (9654-9660). [PMID:33843095] [10.1002/chem.202100752] |
20. Jingbai Wen, Jie Bao. (2021) Improved fermentative γ-aminobutyric acid production by secretory expression of glutamate decarboxylase by Corynebacterium glutamicum. JOURNAL OF BIOTECHNOLOGY, 331 (19). [PMID:33711360] [10.1016/j.jbiotec.2021.03.003] |
21. Hongjie Hui, Yajun Bai, Tai-Ping Fan, Xiaohui Zheng, Yujie Cai. (2020) Biosynthesis of Putrescine from L-arginine Using Engineered Escherichia coli Whole Cells. Catalysts, 10 (9): (947). [PMID:] [10.3390/catal10090947] |
22. Li-Chao Wang, Lian Xu, Xin-Qi Xu, Bing-Mei Su, Juan Lin. (2020) An L-threonine aldolase for asymmetric synthesis of β-hydroxy-α-amino acids. CHEMICAL ENGINEERING SCIENCE, 226 (115812). [PMID:] [10.1016/j.ces.2020.115812] |
23. Zhu Hang-Qin, Tang Xiao-Ling, Zheng Ren-Chao, Zheng Yu-Guo. (2020) Purification and Biochemical Characterization of a Tyrosine Phenol-lyase from Morganella morganii. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 192 (1): (71-84). [PMID:32236865] [10.1007/s12010-020-03301-1] |
24. Hao-Hua Deng, Kai-Yuan Huang, Quan-Hui Fang, Ya-Ping Lv, Shao-Bin He, Hua-Ping Peng, Xing-Hua Xia, Wei Chen. (2020) Schiff base and Lewis acid-base interaction-regulated aggregation/dispersion of gold nanoparticles for colorimetric recognition of rare-earth Sc3+ ions. SENSORS AND ACTUATORS B-CHEMICAL, 311 (127925). [PMID:] [10.1016/j.snb.2020.127925] |
25. Hao-Hua Deng, Kai-Yuan Huang, Shao-Bin He, Li-Ping Xue, Hua-Ping Peng, Dai-Jun Zha, Wei-Ming Sun, Xing-Hua Xia, Wei Chen. (2020) Rational Design of High-Performance Donor–Linker–Acceptor Hybrids Using a Schiff Base for Enabling Photoinduced Electron Transfer. ANALYTICAL CHEMISTRY, 92 (2): (2019–2026). [PMID:31854983] [10.1021/acs.analchem.9b04434] |
26. Lian Xu, Li-Chao Wang, Xin-Qi Xu, Juan Lin. (2019) Characteristics of L-threonine transaldolase for asymmetric synthesis of β-hydroxy-α-amino acids. Catalysis Science & Technology, 9 (21): (5943-5952). [PMID:] [10.1039/C9CY01608B] |
27. Xiao-Ling Tang, Nan-Nan Zhang, Guo-Yan Ye, Yu-Guo Zheng. (2019) Efficient biosynthesis of (R)-3-amino-1-butanol by a novel (R)-selective transaminase from Actinobacteria sp.. JOURNAL OF BIOTECHNOLOGY, 295 (49). [PMID:30853639] [10.1016/j.jbiotec.2019.02.008] |
28. Xiao-Ling Tang, Hui Suo, Ren-Chao Zheng, Yu-Guo Zheng. (2018) An efficient colorimetric high-throughput screening method for synthetic activity of tyrosine phenol-lyase. ANALYTICAL BIOCHEMISTRY, 560 (7). [PMID:30176231] [10.1016/j.ab.2018.08.026] |
29. Zhang Zhi-Jun, Cai Rui-Feng, Xu Jian-He. (2018) Characterization of a new nitrilase from Hoeflea phototrophica DFL-43 for a two-step one-pot synthesis of (S)-β-amino acids. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 102 (14): (6047-6056). [PMID:29744634] [10.1007/s00253-018-9057-7] |
30. Qian Wang, Xiao-Mei He, Xi Chen, Gang-Tian Zhu, Ren-Qi Wang, Yu-Qi Feng. (2017) Pyridoxal 5′-phosphate mediated preparation of immobilized metal affinity material for highly selective and sensitive enrichment of phosphopeptides. JOURNAL OF CHROMATOGRAPHY A, 1499 (30). [PMID:28390667] [10.1016/j.chroma.2017.03.085] |
31. Wu Hua-Lei, Zhang Jian-Dong, Zhang Chao-Feng, Fan Xiao-Jun, Chang Hong-Hong, Wei Wen-Long. (2017) Characterization of Four New Distinct ω-Transaminases from Pseudomonas putida NBRC 14164 for Kinetic Resolution of Racemic Amines and Amino Alcohols. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 181 (3): (972-985). [PMID:27714638] [10.1007/s12010-016-2263-9] |
32. Ailin Xiao, Jing Li, Tianjian Liu, Zhuxi Liu, Chuanfei Wei, Xiaomeng Xu, Qin Li, Jingxin Li. (2016) l-Cysteine enhances nutrient absorption via a cystathionine-β-synthase-derived H2S pathway in rodent jejunum. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 43 (5): (562-568). [PMID:26901099] [10.1111/1440-1681.12562] |
33. S. Tang, D. Huang, N. An, D. Chen, D. Zhao. (2016) A novel pathway for the production of H2S by DAO in rat jejunum. NEUROGASTROENTEROLOGY AND MOTILITY, 28 (5): (687-692). [PMID:26813142] [10.1111/nmo.12765] |
34. Miao Chen, Liya Rong, Xiaoqing Chen. (2015) A simple and sensitive detection of glutamic-pyruvic transaminase activity based on fluorescence quenching of bovine serum albumin. RSC Advances, 5 (125): (103557-103562). [PMID:] [10.1039/C5RA24162F] |
35. Ailin Xiao,Hongjuan Wang,Xin Lu,Jianchun Zhu,Di Huang,Tonghui Xu,Jianqiang Guo,Chuanyong Liu,Jingxin Li. (2015-11-05) H2S, a novel gasotransmitter, involves in gastric accommodation.. Scientific reports, 5 (16086-16086). [PMID:26531221] |