Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | pyridoxal phosphate | 54-47-7 | Codecarboxylase | pyridoxal 5'-phosphate | pyridoxal 5-phosphate | Pyridoxyl phosphate | Pyridoxal P | Pyridoxal-5'-phosphate | Biosechs | Hairoxal | Pidopidon | Pyromijin | Vitazechs | (4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phos |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Grade | Moligand™ |
Associated Targets(Human)
P2RX1 Tchem P2X purinoceptor 1 (1 Activities)
F2 Tclin Thrombin (11687 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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PGR Tclin Progesterone receptor (8562 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
AR Tclin Androgen Receptor (11781 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
MAOA Tclin Monoamine oxidase A (11911 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ACHE Tclin Acetylcholinesterase (18204 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SLC6A4 Tclin Serotonin transporter (12625 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
OPRM1 Tclin Mu opioid receptor (19785 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SLC6A3 Tclin Dopamine transporter (10535 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
KCNH2 Tclin HERG (29587 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PDE4A Tclin Phosphodiesterase 4A (1943 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ADORA3 Tchem Adenosine A3 receptor (15931 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
HRH3 Tclin Histamine H3 receptor (10389 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
P2RX4 Tchem P2X purinoceptor 4 (516 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
P2RX1 Tchem P2X purinoceptor 1 (328 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
KDR Tclin Vascular endothelial growth factor receptor 2 (20924 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
CAD Tchem Dihydroorotase (27 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PTPRB Tchem Receptor-type tyrosine-protein phosphatase beta (330 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
ACP1 Tchem Low molecular weight phosphotyrosine protein phosphatase (1161 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1/alpha-2/beta-2/gamma-2 (1034 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Associated Targets(non-human)
P2rx2 P2X purinoceptor 2 (106 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
P2rx3 P2X purinoceptor 3 (632 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Hdac6 Histone deacetylase 6 (222 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Rattus norvegicus (775804 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
rep Replicase polyprotein 1ab (378 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Trans-sialidase (51 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
SARS-CoV-2 (38078 Activities)
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Names and Identifiers
| IUPAC Name | (4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl dihydrogen phosphate |
|---|---|
| INCHI | InChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14) |
| InChi Key | NGVDGCNFYWLIFO-UHFFFAOYSA-N |
| Canonical SMILES | CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O |
| Isomeric SMILES | CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O |
| PubChem CID | 1051 |
| Molecular Weight | 247.14 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Chemical and Physical Properties
| Melt Point(°C) | 140-143°C |
|---|
Related Documents
FAQs and Articles
Citations of This Product
| 1. Zixin Teng, Xuewei Pan, Yunran Liu, Jiajia You, Hengwei Zhang, Zhenqiang Zhao, Zhina Qiao, Zhiming Rao. (2024) Engineering serine hydroxymethyltransferases for efficient synthesis of L-serine in Escherichia coli. BIORESOURCE TECHNOLOGY, 393 (22): (130153). [PMID:38052329] |
| 2. Nan Jiang, Xiaotong Du, Liangyu Zheng. (2023) Highly efficient synthesis of chiral lactams by using a ω-transaminase from Bacillus megaterium and its mutant enzymes. Molecular Catalysis, 547 (113364). [PMID:] |
| 3. Hongpeng Wang, Mercy Vimbai Masuku, Yachen Tao, Jiayao Yang, Yi Kuang, Changjiang Lyu, Jun Huang, Shengxiang Yang. (2023) Improved Stability and Catalytic Efficiency of ω-Transaminase in Aqueous Mixture of Deep Eutectic Solvents. MOLECULES, 28 (9): (3895). [PMID:37175305] |
| 4. Juanjuan Ding, Wenyan Ba, Shengping You, Wei Qi, Rongxin Su. (2023) Development of an oil-sealed anaerobic fermentation process for high production of γ-aminobutyric acid with Lactobacillus brevis isolated by directional colorimetric screening. BIOCHEMICAL ENGINEERING JOURNAL, 194 (108893). [PMID:] |
| 5. Xiao-Ling Tang, Ning Li, Yan-Lai Liu, Jing-Peng Li, Kai-Xuan Zhao, Zhi-Qiang Liu, Yu-Guo Zheng. (2023) Engineering O-Succinyl-L-Homoserine Mercaptotransferase for Efficient L-Methionine Biosynthesis by Fermentation-Enzymatic Coupling Route. ADVANCED SYNTHESIS & CATALYSIS, 365 (7): (1048-1057). [PMID:] |
| 6. Xingchang Cha, Juanjuan Ding, Wenyan Ba, Shengping You, Wei Qi, Rongxin Su. (2023) High Production of γ-Aminobutyric Acid by Activating the xyl Operon of Lactobacillus brevis. ACS Omega, 8 (8): (8101–8109). [PMID:36873027] |
| 7. Shiyi Wang, Yiwen Zhao, Shufen Mao, Jiang Zhu, Yangyang Zhan, Dongbo Cai, Xin Ma, Dong Wang, Shouwen Chen. (2023) Enhancing the activity of disulfide-bond-containing proteins via promoting disulfide bond formation in Bacillus licheniformis. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 233 (123468). [PMID:36731702] |
| 8. Lian Xu, Dan Nie, Bing-Mei Su, Xin-Qi Xu, Juan Lin. (2023) A chemoenzymatic strategy for the efficient synthesis of amphenicol antibiotic chloramphenicol mediated by an engineered L-threonine transaldolase with high activity and stereoselectivity. Catalysis Science & Technology, 13 (3): (684-693). [PMID:] |
| 9. Sai Fang, Haoran Yu, Lanxin Xiao, Zhe Wang, Yixuan Lei, Gang Xu, Lirong Yang, Wenlong Zheng, Jianping Wu. (2022) Counteracting the Activity-Diastereoselectivity Trade-Off of l-Threonine Aldolase by Regulating the Proton Transfer Microenvironment. ADVANCED SYNTHESIS & CATALYSIS, 364 (24): (4363-4370). [PMID:] |
| 10. Kai Yuan, Kai Huang, Yiqi Yang, Yixuan Lin, Yihao Liu, Fupeng Li, Yakun Liang, Haishuang Chang, Yuhui Chen, Tingting Tang, Shengbing Yang. (2022) Multi-roles of nanoscale bismuth metal-organic frameworks: Infectious photoacoustic probe and inhibitor of antibiotics tolerant bacteria via targeting endogenous H2S. Nano Today, 47 (101683). [PMID:] |
| 11. Guozeng Wang, Zhihao Jiang, Qing Xiao, Chang Jiang, Xian'ai Shi. (2022) Visible spectrophotometric assay for characterization of ω-transaminases. ANALYTICAL BIOCHEMISTRY, 658 (114933). [PMID:36208685] |
| 12. Deng Hao-Hua, Yang Hui-Jing, Huang Kai-Yuan, Zheng Yi-Jing, Xu Ying-Ying, Peng Hua-Ping, Liu Yin-Huan, Chen Wei, Hong Guo-Lin. (2022) Antenna effect of pyridoxal phosphate on the fluorescence of mitoxantrone-silicon nanoparticles and its application in alkaline phosphatase assay. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (17): (4877-4884). [PMID:35576012] |
| 13. Wang Dong-En, You Shangqi, Huo Wenjing, Han Xiang, Xu Huiyun. (2022) Colorimetric detection of alkaline phosphatase activity based on pyridoxal phosphate–induced chromatic switch of polydiacetylene nano-liposomes. MICROCHIMICA ACTA, 189 (2): (1-12). [PMID:35067757] |
| 14. Hang-Qin Zhu, Wen-Ye Hu, Xiao-Ling Tang, Ren-Chao Zheng, Yu-Guo Zheng. (2022) High-throughput assay of tyrosine phenol-lyase activity using a cascade of enzymatic reactions. ANALYTICAL BIOCHEMISTRY, 640 (114547). [PMID:35026146] |
| 15. Jiahao Yao, Zhuang Li, Xiuling Ji, Yaju Xue, Baozeng Ren, Hai Zhao, Yuhong Huang. (2021) Novel enzyme-metal-organic framework composite for efficient cadaverine production. BIOCHEMICAL ENGINEERING JOURNAL, 176 (108222). [PMID:] |
| 16. Ailin Xiao,Hongjuan Wang,Xin Lu,Jianchun Zhu,Di Huang,Tonghui Xu,Jianqiang Guo,Chuanyong Liu,Jingxin Li. (2015-11-05) H2S, a novel gasotransmitter, involves in gastric accommodation.. Scientific reports, 5 (16086-16086). [PMID:26531221] |
References
| 1. Zixin Teng, Xuewei Pan, Yunran Liu, Jiajia You, Hengwei Zhang, Zhenqiang Zhao, Zhina Qiao, Zhiming Rao. (2024) Engineering serine hydroxymethyltransferases for efficient synthesis of L-serine in Escherichia coli. BIORESOURCE TECHNOLOGY, 393 (22): (130153). [PMID:38052329] |
| 2. Nan Jiang, Xiaotong Du, Liangyu Zheng. (2023) Highly efficient synthesis of chiral lactams by using a ω-transaminase from Bacillus megaterium and its mutant enzymes. Molecular Catalysis, 547 (113364). [PMID:] |
| 3. Hongpeng Wang, Mercy Vimbai Masuku, Yachen Tao, Jiayao Yang, Yi Kuang, Changjiang Lyu, Jun Huang, Shengxiang Yang. (2023) Improved Stability and Catalytic Efficiency of ω-Transaminase in Aqueous Mixture of Deep Eutectic Solvents. MOLECULES, 28 (9): (3895). [PMID:37175305] |
| 4. Juanjuan Ding, Wenyan Ba, Shengping You, Wei Qi, Rongxin Su. (2023) Development of an oil-sealed anaerobic fermentation process for high production of γ-aminobutyric acid with Lactobacillus brevis isolated by directional colorimetric screening. BIOCHEMICAL ENGINEERING JOURNAL, 194 (108893). [PMID:] |
| 5. Xiao-Ling Tang, Ning Li, Yan-Lai Liu, Jing-Peng Li, Kai-Xuan Zhao, Zhi-Qiang Liu, Yu-Guo Zheng. (2023) Engineering O-Succinyl-L-Homoserine Mercaptotransferase for Efficient L-Methionine Biosynthesis by Fermentation-Enzymatic Coupling Route. ADVANCED SYNTHESIS & CATALYSIS, 365 (7): (1048-1057). [PMID:] |
| 6. Xingchang Cha, Juanjuan Ding, Wenyan Ba, Shengping You, Wei Qi, Rongxin Su. (2023) High Production of γ-Aminobutyric Acid by Activating the xyl Operon of Lactobacillus brevis. ACS Omega, 8 (8): (8101–8109). [PMID:36873027] |
| 7. Shiyi Wang, Yiwen Zhao, Shufen Mao, Jiang Zhu, Yangyang Zhan, Dongbo Cai, Xin Ma, Dong Wang, Shouwen Chen. (2023) Enhancing the activity of disulfide-bond-containing proteins via promoting disulfide bond formation in Bacillus licheniformis. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 233 (123468). [PMID:36731702] |
| 8. Lian Xu, Dan Nie, Bing-Mei Su, Xin-Qi Xu, Juan Lin. (2023) A chemoenzymatic strategy for the efficient synthesis of amphenicol antibiotic chloramphenicol mediated by an engineered L-threonine transaldolase with high activity and stereoselectivity. Catalysis Science & Technology, 13 (3): (684-693). [PMID:] |
| 9. Sai Fang, Haoran Yu, Lanxin Xiao, Zhe Wang, Yixuan Lei, Gang Xu, Lirong Yang, Wenlong Zheng, Jianping Wu. (2022) Counteracting the Activity-Diastereoselectivity Trade-Off of l-Threonine Aldolase by Regulating the Proton Transfer Microenvironment. ADVANCED SYNTHESIS & CATALYSIS, 364 (24): (4363-4370). [PMID:] |
| 10. Kai Yuan, Kai Huang, Yiqi Yang, Yixuan Lin, Yihao Liu, Fupeng Li, Yakun Liang, Haishuang Chang, Yuhui Chen, Tingting Tang, Shengbing Yang. (2022) Multi-roles of nanoscale bismuth metal-organic frameworks: Infectious photoacoustic probe and inhibitor of antibiotics tolerant bacteria via targeting endogenous H2S. Nano Today, 47 (101683). [PMID:] |
| 11. Guozeng Wang, Zhihao Jiang, Qing Xiao, Chang Jiang, Xian'ai Shi. (2022) Visible spectrophotometric assay for characterization of ω-transaminases. ANALYTICAL BIOCHEMISTRY, 658 (114933). [PMID:36208685] |
| 12. Deng Hao-Hua, Yang Hui-Jing, Huang Kai-Yuan, Zheng Yi-Jing, Xu Ying-Ying, Peng Hua-Ping, Liu Yin-Huan, Chen Wei, Hong Guo-Lin. (2022) Antenna effect of pyridoxal phosphate on the fluorescence of mitoxantrone-silicon nanoparticles and its application in alkaline phosphatase assay. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (17): (4877-4884). [PMID:35576012] |
| 13. Wang Dong-En, You Shangqi, Huo Wenjing, Han Xiang, Xu Huiyun. (2022) Colorimetric detection of alkaline phosphatase activity based on pyridoxal phosphate–induced chromatic switch of polydiacetylene nano-liposomes. MICROCHIMICA ACTA, 189 (2): (1-12). [PMID:35067757] |
| 14. Hang-Qin Zhu, Wen-Ye Hu, Xiao-Ling Tang, Ren-Chao Zheng, Yu-Guo Zheng. (2022) High-throughput assay of tyrosine phenol-lyase activity using a cascade of enzymatic reactions. ANALYTICAL BIOCHEMISTRY, 640 (114547). [PMID:35026146] |
| 15. Jiahao Yao, Zhuang Li, Xiuling Ji, Yaju Xue, Baozeng Ren, Hai Zhao, Yuhong Huang. (2021) Novel enzyme-metal-organic framework composite for efficient cadaverine production. BIOCHEMICAL ENGINEERING JOURNAL, 176 (108222). [PMID:] |
| 16. Ailin Xiao,Hongjuan Wang,Xin Lu,Jianchun Zhu,Di Huang,Tonghui Xu,Jianqiang Guo,Chuanyong Liu,Jingxin Li. (2015-11-05) H2S, a novel gasotransmitter, involves in gastric accommodation.. Scientific reports, 5 (16086-16086). [PMID:26531221] |