Determine the necessary mass, volume, or concentration for preparing a solution.
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Synonyms | pyridoxine | 65-23-6 | vitamin B6 | Pyridoxol | Pyridoxin | Gravidox | 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine | Adermine | Hydoxin | Pyridoxolum | 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl- | 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol | 5-Hydroxy-6-methyl-3,4-pyridi |
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Specifications & Purity | 10mM in DMSO |
Biochemical and Physiological Mechanisms | Pyridoxine (Vitamin B6) is a form of vitamin B6. Other forms include the aldehyde pyridoxal and the amide pyridoxamine. Pyridoxine is used in cell culture and other applications as a precursor to pyridoxal phosphate. |
Storage Temp | Protected from light,Store at -80°C |
Shipped In | Ice chest + Ice pads |
Product Description | Pyridoxine is used in cell culture and other applications as a precursor to pyridoxal phosphate. It has been used as a standard in RP-HPLC (reversed phase high performance liquid chromatography) method. Pyridoxine has been used as a diet supplement to study lipid profile in rats. |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol |
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INCHI | InChI=1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3 |
InChi Key | LXNHXLLTXMVWPM-UHFFFAOYSA-N |
Canonical SMILES | CC1=NC=C(C(=C1O)CO)CO |
Isomeric SMILES | CC1=NC=C(C(=C1O)CO)CO |
WGK Germany | 3 |
RTECS | UV1300000 |
Alternate CAS | 58-56-0 |
PubChem CID | 1054 |
Molecular Weight | 169.18 |
Enter Lot Number to search for COA:
Sensitivity | light sensitive |
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Melt Point(°C) | 159-162°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | UV1300000 |
1. Ye Shu, Tong Chen, Tao Liu, Hechen Xu, Jinjin He, Zhihui Cai, Wanning Zhu, Zihan Zhao, Jun Jiang. (2023) Preparation and characterization of mixed-mode hydrophilic stationary phase based on triple hydrophilic functionalized moieties and its application to traditional Chinese herbal compound. MICROCHEMICAL JOURNAL, 191 (108863). [PMID:] |
2. Luo Jialun, Jiang Cheng, Zhao Jihua, Zhao Luyao, Zheng Peizhu, Fang Jian. (2023) Hierarchical tungsten-doped bimetallic selenides nanosheets arrays/nickel foam composite electrode as efficient gallic acid electrochemical sensor. MICROCHIMICA ACTA, 190 (4): (1-13). [PMID:37000326] |
3. Juanjuan Ding, Wenyan Ba, Shengping You, Wei Qi, Rongxin Su. (2023) Development of an oil-sealed anaerobic fermentation process for high production of γ-aminobutyric acid with Lactobacillus brevis isolated by directional colorimetric screening. BIOCHEMICAL ENGINEERING JOURNAL, 194 (108893). [PMID:] |
4. Yuan Kaisong, Huang Rui, Gong Kaishuo, Xiao Ziyi, Chen Jialin, Cai Siyao, Shen Jiayi, Xiong Zuer, Lin Zhexuan. (2023) Smartphone-based hand-held polarized light microscope for on-site pharmaceutical crystallinity characterization. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 415 (18): (4401-4410). [PMID:36786836] |
5. Tong Chen, Shuya Wang, Xufang Zong, Bingxiang Li, Ye Shu, Xinyuan Di, Wanning Zhu, Guangsan Song, Jun Jiang. (2023) Preparation and application of sulfated lily polysaccharide bridged polyhedral oligomeric silsesquioxane hybrid organosilicas as stationary phase. JOURNAL OF CHROMATOGRAPHY A, 1691 (463822). [PMID:36709551] |
6. Xijuan Tu, Yunmin Tao, Jiaxu Chen, Chunping Du, Qian Jin, Yuchang He, Ji Yang, Shaokang Huang, Wenbin Chen. (2022) Dipicolinic Acid-Tb3+/Eu3+ Lanthanide Fluorescence Sensor Array for Rapid and Visual Discrimination of Botanical Origin of Honey. Foods, 11 (21): (3388). [PMID:36360001] |
7. Nanjun Li, Chongyang Wang, Liangjun Chen, Cui Ye, Yongwu Peng. (2022) Ultrathin Covalent Organic Framework Nanosheets/Ti3C2Tx-Based Photoelectrochemical Biosensor for Efficient Detection of Prostate-Specific Antigen. MOLECULES, 27 (19): (6732). [PMID:36235265] |
8. Weng Chunyue, Mi Zheyan, Li Meijing, Qin Haibin, Hu Zhongce, Liu Zhiqiang, Zheng Yuguo, Wang Yuanshan. (2022) Improvement of S-adenosyl-L-methionine production in Saccharomyces cerevisiae by atmospheric and room temperature plasma-ultraviolet compound mutagenesis and droplet microfluidic adaptive evolution. 3 Biotech, 12 (9): (1-15). [PMID:35975026] |
9. Xiuling Ji, Suping Wang, Yiyong Luo, Xiaotian Yuan, Yunlin Wei, Qi Zhang, Kunhao Qin, Yujiao Tu. (2021) Green synthesis of weissella-derived fluorescence carbon dots for microbial staining, cell imaging and dual sensing of vitamin B12 and hexavalent chromium. DYES AND PIGMENTS, 184 (108818). [PMID:] |
10. Naiyi Yin, Zeliang Han, Huili Du, Pengfei Wang, Yunpeng Li, Xiaochen Chen, Guoxin Sun, Yanshan Cui, Zhengyi Hu. (2020) Effect of dietary vitamins in oral bioaccessibility of lead in contaminated soils based on the physiologically based extraction test. SCIENCE OF THE TOTAL ENVIRONMENT, 747 (141299). [PMID:32791414] |
11. Siliang Liu, Chunyu Liu, Yu Ren, Shangqi Kuang, Chengcheng Zhou, Hongxing Cai, Zhihai Yao. (2020) Fluorescence spectra of nutrients in chicken and skin under baking conditions. OPTIK, 218 (164795). [PMID:] |
12. Shi-Qi Zhang, Jing Li, Lin Li, Xiaoting Yuan, Li Xu, Zhi-guo Shi. (2020) Fast separation of water-soluble vitamins by hydrophilic interaction liquid chromatography based on submicrometer flow-through silica microspheres. FOOD CHEMISTRY, 307 (125531). [PMID:31644979] |
13. Hui He, Pir Muhammad, Zhanchen Guo, Qiling Peng, Haifeng Lu, Zhen Liu. (2019) Controllably prepared molecularly imprinted core-shell plasmonic nanostructure for plasmon-enhanced fluorescence assay. BIOSENSORS & BIOELECTRONICS, 146 (111733). [PMID:31600624] |
14. Mengling Lin, Yingjie Guo, Zhiyong Liang, Xuesong Zhao, Jianan Chen, Yilin Wang. (2019) Simple and fast determination of biothiols using Fe3+-3, 3′, 5, 5′-tetramethylbenzidine as a colorimetric probe. MICROCHEMICAL JOURNAL, 147 (319). [PMID:] |
15. Zhenping Liu, Mingliang Jin, Jieping Cao, Ruiwen Niu, Pengfei Li, Guofu Zhou, Ying Yu, Albert van den Berg, Lingling Shui. (2018) Electrochemical sensor integrated microfluidic device for sensitive and simultaneous quantification of dopamine and 5-hydroxytryptamine. SENSORS AND ACTUATORS B-CHEMICAL, 273 (873). [PMID:] |
16. Huihui Li, Wei Liu, Fengyuan Zhang, Xinyue Zhu, Liqiu Huang, Haixia Zhang. (2018) Highly Selective Fluorescent Probe Based on Hydroxylation of Phenylboronic Acid Pinacol Ester for Detection of Tyrosinase in Cells. ANALYTICAL CHEMISTRY, 90 (1): (855–858). [PMID:29198104] |
17. Qiqin Wang, Huihui Wu, Kun Peng, Hanying Jin, Huikai Shao, Yuqiang Wang, Jacques Crommen, Zhengjin Jiang. (2018) Hydrophilic polymeric monoliths containing choline phosphate for separation science applications. ANALYTICA CHIMICA ACTA, 999 (184). [PMID:29254571] |
18. Meihui Fan, Guowen Zhang, Junhui Pan, Deming Gong. (2017) An inhibition mechanism of dihydromyricetin on tyrosinase and the joint effects of vitamins B6, D3 or E. Food & Function, 8 (7): (2601-2610). [PMID:28686246] |
19. Houmei Liu, Jia Chen, Zhan Li, Makoto Takafuji, Hirotaka Ihara, Hongdeng Qiu. (2017) A new route for synthesis of N-methylimidazolium-grafted silica stationary phase and reevaluation in hydrophilic interaction liquid chromatography. TALANTA, 164 (137). [PMID:28107907] |
20. Yuliang Li, Xiaojia Lu, Qi Zhu, Rong Huang, Jing Hu, Hongbin Yang, Yiliang Yao. (2016) Phase behavior of quaternary aqueous two-phase systems: Influence factors and extraction mechanism study. FLUID PHASE EQUILIBRIA, 430 (101). [PMID:] |
21. Daofan Ma, Xiaofeng Jiang, Guoqiang Wei, Chunying Zhu. (2015) Volumetric and Viscometric Studies of Amino Acids in Vitamin B6 Aqueous Solutions at Various Temperatures. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 60 (5): (1279–1290). [PMID:] |
22. Zifei Wang, Zhipeng Wang, Hui Zhang, Xuemin Duan, Jingkun Xu, Yangping Wen. (2015) Electrochemical sensing application of poly(acrylic acid modified EDOT-co-EDOT):PSS and its inorganic nanocomposite with high soaking stability, adhesion ability and flexibility. RSC Advances, 5 (16): (12237-12247). [PMID:] |
23. Cheng Xiao-Dong, Peng Xi-Tian, Yu Qiong-Wei, Yuan Bi-Feng, Feng Yu-Qi. (2013) Preparation of a Novel Amino-Phosphate Zwitterionic Stationary Phase for Hydrophilic Interaction Chromatography. CHROMATOGRAPHIA, 76 (23): (1569-1576). [PMID:] |
24. Xi-Tian Peng, Tao Liu, Shu-Xian Ji, Yu-Qi Feng. (2013) Preparation of a novel carboxyl stationary phase by “thiol-ene” click chemistry for hydrophilic interaction chromatography. JOURNAL OF SEPARATION SCIENCE, 36 (16): (2571-2577). [PMID:23749722] |
25. Xiao-Dong Cheng,Yan-Hong Hao,Xi-Tian Peng,Bi-Feng Yuan,Zhi-Guo Shi,Yu-Qi Feng. (2015-05-13) Preparation and chromatographic evaluation of zwitterionic stationary phases with controllable ratio of positively and negatively charged groups.. Talanta, 141 (8-14). [PMID:25966373] |
1. Ye Shu, Tong Chen, Tao Liu, Hechen Xu, Jinjin He, Zhihui Cai, Wanning Zhu, Zihan Zhao, Jun Jiang. (2023) Preparation and characterization of mixed-mode hydrophilic stationary phase based on triple hydrophilic functionalized moieties and its application to traditional Chinese herbal compound. MICROCHEMICAL JOURNAL, 191 (108863). [PMID:] |
2. Luo Jialun, Jiang Cheng, Zhao Jihua, Zhao Luyao, Zheng Peizhu, Fang Jian. (2023) Hierarchical tungsten-doped bimetallic selenides nanosheets arrays/nickel foam composite electrode as efficient gallic acid electrochemical sensor. MICROCHIMICA ACTA, 190 (4): (1-13). [PMID:37000326] |
3. Juanjuan Ding, Wenyan Ba, Shengping You, Wei Qi, Rongxin Su. (2023) Development of an oil-sealed anaerobic fermentation process for high production of γ-aminobutyric acid with Lactobacillus brevis isolated by directional colorimetric screening. BIOCHEMICAL ENGINEERING JOURNAL, 194 (108893). [PMID:] |
4. Yuan Kaisong, Huang Rui, Gong Kaishuo, Xiao Ziyi, Chen Jialin, Cai Siyao, Shen Jiayi, Xiong Zuer, Lin Zhexuan. (2023) Smartphone-based hand-held polarized light microscope for on-site pharmaceutical crystallinity characterization. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 415 (18): (4401-4410). [PMID:36786836] |
5. Tong Chen, Shuya Wang, Xufang Zong, Bingxiang Li, Ye Shu, Xinyuan Di, Wanning Zhu, Guangsan Song, Jun Jiang. (2023) Preparation and application of sulfated lily polysaccharide bridged polyhedral oligomeric silsesquioxane hybrid organosilicas as stationary phase. JOURNAL OF CHROMATOGRAPHY A, 1691 (463822). [PMID:36709551] |
6. Xijuan Tu, Yunmin Tao, Jiaxu Chen, Chunping Du, Qian Jin, Yuchang He, Ji Yang, Shaokang Huang, Wenbin Chen. (2022) Dipicolinic Acid-Tb3+/Eu3+ Lanthanide Fluorescence Sensor Array for Rapid and Visual Discrimination of Botanical Origin of Honey. Foods, 11 (21): (3388). [PMID:36360001] |
7. Nanjun Li, Chongyang Wang, Liangjun Chen, Cui Ye, Yongwu Peng. (2022) Ultrathin Covalent Organic Framework Nanosheets/Ti3C2Tx-Based Photoelectrochemical Biosensor for Efficient Detection of Prostate-Specific Antigen. MOLECULES, 27 (19): (6732). [PMID:36235265] |
8. Weng Chunyue, Mi Zheyan, Li Meijing, Qin Haibin, Hu Zhongce, Liu Zhiqiang, Zheng Yuguo, Wang Yuanshan. (2022) Improvement of S-adenosyl-L-methionine production in Saccharomyces cerevisiae by atmospheric and room temperature plasma-ultraviolet compound mutagenesis and droplet microfluidic adaptive evolution. 3 Biotech, 12 (9): (1-15). [PMID:35975026] |
9. Xiuling Ji, Suping Wang, Yiyong Luo, Xiaotian Yuan, Yunlin Wei, Qi Zhang, Kunhao Qin, Yujiao Tu. (2021) Green synthesis of weissella-derived fluorescence carbon dots for microbial staining, cell imaging and dual sensing of vitamin B12 and hexavalent chromium. DYES AND PIGMENTS, 184 (108818). [PMID:] |
10. Naiyi Yin, Zeliang Han, Huili Du, Pengfei Wang, Yunpeng Li, Xiaochen Chen, Guoxin Sun, Yanshan Cui, Zhengyi Hu. (2020) Effect of dietary vitamins in oral bioaccessibility of lead in contaminated soils based on the physiologically based extraction test. SCIENCE OF THE TOTAL ENVIRONMENT, 747 (141299). [PMID:32791414] |
11. Siliang Liu, Chunyu Liu, Yu Ren, Shangqi Kuang, Chengcheng Zhou, Hongxing Cai, Zhihai Yao. (2020) Fluorescence spectra of nutrients in chicken and skin under baking conditions. OPTIK, 218 (164795). [PMID:] |
12. Shi-Qi Zhang, Jing Li, Lin Li, Xiaoting Yuan, Li Xu, Zhi-guo Shi. (2020) Fast separation of water-soluble vitamins by hydrophilic interaction liquid chromatography based on submicrometer flow-through silica microspheres. FOOD CHEMISTRY, 307 (125531). [PMID:31644979] |
13. Hui He, Pir Muhammad, Zhanchen Guo, Qiling Peng, Haifeng Lu, Zhen Liu. (2019) Controllably prepared molecularly imprinted core-shell plasmonic nanostructure for plasmon-enhanced fluorescence assay. BIOSENSORS & BIOELECTRONICS, 146 (111733). [PMID:31600624] |
14. Mengling Lin, Yingjie Guo, Zhiyong Liang, Xuesong Zhao, Jianan Chen, Yilin Wang. (2019) Simple and fast determination of biothiols using Fe3+-3, 3′, 5, 5′-tetramethylbenzidine as a colorimetric probe. MICROCHEMICAL JOURNAL, 147 (319). [PMID:] |
15. Zhenping Liu, Mingliang Jin, Jieping Cao, Ruiwen Niu, Pengfei Li, Guofu Zhou, Ying Yu, Albert van den Berg, Lingling Shui. (2018) Electrochemical sensor integrated microfluidic device for sensitive and simultaneous quantification of dopamine and 5-hydroxytryptamine. SENSORS AND ACTUATORS B-CHEMICAL, 273 (873). [PMID:] |
16. Huihui Li, Wei Liu, Fengyuan Zhang, Xinyue Zhu, Liqiu Huang, Haixia Zhang. (2018) Highly Selective Fluorescent Probe Based on Hydroxylation of Phenylboronic Acid Pinacol Ester for Detection of Tyrosinase in Cells. ANALYTICAL CHEMISTRY, 90 (1): (855–858). [PMID:29198104] |
17. Qiqin Wang, Huihui Wu, Kun Peng, Hanying Jin, Huikai Shao, Yuqiang Wang, Jacques Crommen, Zhengjin Jiang. (2018) Hydrophilic polymeric monoliths containing choline phosphate for separation science applications. ANALYTICA CHIMICA ACTA, 999 (184). [PMID:29254571] |
18. Meihui Fan, Guowen Zhang, Junhui Pan, Deming Gong. (2017) An inhibition mechanism of dihydromyricetin on tyrosinase and the joint effects of vitamins B6, D3 or E. Food & Function, 8 (7): (2601-2610). [PMID:28686246] |
19. Houmei Liu, Jia Chen, Zhan Li, Makoto Takafuji, Hirotaka Ihara, Hongdeng Qiu. (2017) A new route for synthesis of N-methylimidazolium-grafted silica stationary phase and reevaluation in hydrophilic interaction liquid chromatography. TALANTA, 164 (137). [PMID:28107907] |
20. Yuliang Li, Xiaojia Lu, Qi Zhu, Rong Huang, Jing Hu, Hongbin Yang, Yiliang Yao. (2016) Phase behavior of quaternary aqueous two-phase systems: Influence factors and extraction mechanism study. FLUID PHASE EQUILIBRIA, 430 (101). [PMID:] |
21. Daofan Ma, Xiaofeng Jiang, Guoqiang Wei, Chunying Zhu. (2015) Volumetric and Viscometric Studies of Amino Acids in Vitamin B6 Aqueous Solutions at Various Temperatures. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 60 (5): (1279–1290). [PMID:] |
22. Zifei Wang, Zhipeng Wang, Hui Zhang, Xuemin Duan, Jingkun Xu, Yangping Wen. (2015) Electrochemical sensing application of poly(acrylic acid modified EDOT-co-EDOT):PSS and its inorganic nanocomposite with high soaking stability, adhesion ability and flexibility. RSC Advances, 5 (16): (12237-12247). [PMID:] |
23. Cheng Xiao-Dong, Peng Xi-Tian, Yu Qiong-Wei, Yuan Bi-Feng, Feng Yu-Qi. (2013) Preparation of a Novel Amino-Phosphate Zwitterionic Stationary Phase for Hydrophilic Interaction Chromatography. CHROMATOGRAPHIA, 76 (23): (1569-1576). [PMID:] |
24. Xi-Tian Peng, Tao Liu, Shu-Xian Ji, Yu-Qi Feng. (2013) Preparation of a novel carboxyl stationary phase by “thiol-ene” click chemistry for hydrophilic interaction chromatography. JOURNAL OF SEPARATION SCIENCE, 36 (16): (2571-2577). [PMID:23749722] |
25. Xiao-Dong Cheng,Yan-Hong Hao,Xi-Tian Peng,Bi-Feng Yuan,Zhi-Guo Shi,Yu-Qi Feng. (2015-05-13) Preparation and chromatographic evaluation of zwitterionic stationary phases with controllable ratio of positively and negatively charged groups.. Talanta, 141 (8-14). [PMID:25966373] |