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Basic Description
| Synonyms | pyridoxine|65-23-6|vitamin B6|Pyridoxol|Pyridoxin|Gravidox|3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine|Adermine|Hydoxin|Pyridoxolum|3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-|4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol|5-Hydroxy-6-methyl-3,4-pyridi |
|---|---|
| Specifications & Purity | 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Pyridoxine (Vitamin B6) is a form of vitamin B6. Other forms include the aldehyde pyridoxal and the amide pyridoxamine. Pyridoxine is used in cell culture and other applications as a precursor to pyridoxal phosphate. |
| Storage Temp | Protected from light,Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | Pyridoxine is used in cell culture and other applications as a precursor to pyridoxal phosphate. It has been used as a standard in RP-HPLC (reversed phase high performance liquid chromatography) method. Pyridoxine has been used as a diet supplement to study lipid profile in rats. |
Associated Targets
CYP1A2 Tchem Cytochrome P450 1A2 0 Activities
CYP2D6 Tclin Cytochrome P450 2D6 0 Activities
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CYP2C19 Tchem Cytochrome P450 2C19 0 Activities
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DRD1 Tclin D(1A) dopamine receptor 0 Activities
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CYP3A4 Tclin Cytochrome P450 3A4 0 Activities
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ESR1 Tclin Estrogen receptor 0 Activities
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GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities
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CYP2C9 Tchem Cytochrome P450 2C9 0 Activities
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HRH3 Tclin Histamine H3 receptor 0 Activities
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HSD17B10 Tchem 3-hydroxyacyl-CoA dehydrogenase type-2 0 Activities
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HDAC6 Tclin Histone deacetylase 6 0 Activities
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SLC6A2 Tclin Sodium-dependent noradrenaline transporter 0 Activities
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SLC6A3 Tclin Sodium-dependent dopamine transporter 0 Activities
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SLC6A4 Tclin Sodium-dependent serotonin transporter 0 Activities
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PGR Tclin Progesterone receptor 0 Activities
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PDE3A Tclin cGMP-inhibited 3',5'-cyclic phosphodiesterase A 0 Activities
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PTGS1 Tclin Prostaglandin G/H synthase 1 0 Activities
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PDE4A Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4A 0 Activities
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HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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PDXK Tbio Pyridoxal kinase 0 Activities
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DRD3 Tclin D(3) dopamine receptor 0 Activities
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KDR Tclin Vascular endothelial growth factor receptor 2 0 Activities
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CHRM2 Tclin Muscarinic acetylcholine receptor M2 0 Activities
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ACHE Tclin Acetylcholinesterase 0 Activities
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ABCB11 Tchem Bile salt export pump 0 Activities
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CHRM1 Tclin Muscarinic acetylcholine receptor M1 0 Activities
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ADRA2A Tclin Alpha-2A adrenergic receptor 0 Activities
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ADRA1A Tclin Alpha-1A adrenergic receptor 0 Activities
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AR Tclin Androgen receptor 0 Activities
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MAOA Tclin Amine oxidase [flavin-containing] A 0 Activities
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ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities
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HTR1A Tclin 5-hydroxytryptamine receptor 1A 0 Activities
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ADORA3 Tchem Adenosine receptor A3 0 Activities
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HTR2B Tclin 5-hydroxytryptamine receptor 2B 0 Activities
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TBXA2R Tclin Thromboxane A2 receptor 0 Activities
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F2 Tclin Prothrombin 0 Activities
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KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 0 Activities
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OPRM1 Tclin Mu-type opioid receptor 0 Activities
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KDM4E Tchem Lysine-specific demethylase 4E 0 Activities
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Names and Identifiers
| IUPAC Name | 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol |
|---|---|
| INCHI | InChI=1S/C8H11NO3/c1-5-8(12)7(4-11)6(3-10)2-9-5/h2,10-12H,3-4H2,1H3 |
| InChi Key | LXNHXLLTXMVWPM-UHFFFAOYSA-N |
| Canonical SMILES | CC1=NC=C(C(=C1O)CO)CO |
| Isomeric SMILES | CC1=NC=C(C(=C1O)CO)CO |
| WGK Germany | 3 |
| RTECS | UV1300000 |
| Alternate CAS | 58-56-0 |
| PubChem CID | 1054 |
| Molecular Weight | 169.18 |
Certificates
Certificate of Analysis(COA)
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Chemical and Physical Properties
| Sensitivity | light sensitive |
|---|---|
| Melt Point(°C) | 159-162°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
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| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |
| RTECS | UV1300000 |