QL-IX-55 , CAS No.1223002-54-7

Item Number
Q128082
Grouped product items
SKUSizeAvailabilityPrice Qty
Q128082-5mg
5mg
Available within 8-12 weeks(?)
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$1,845.90

Basic Description

SynonymsQL-IX-55 | 1223002-54-7 | 9-(6-aminopyridin-3-yl)-1-(4-fluoro-3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one | CHEMBL1765605 | 9-(6-aminopyridin-3-yl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2-one | 9-(6-Amino-3-pyridinyl)-1-[
Biochemical and Physiological Mechanisms

The functional target of QL-IX-55 is the ATP-binding site of TOR2 as evidenced by the discovery of resistant alleles of TOR2 through rational design and unbiased selection strategies. QL-IX-55 is capable of potently inhibiting both TOR co

Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

MTOR Tclin Serine/threonine-protein kinase mTOR (13850 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

PIK3CA PI3-kinase p110-alpha subunit (51 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 9-(6-aminopyridin-3-yl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2-one
INCHI InChI=1S/C24H14F4N4O/c25-19-5-4-16(10-18(19)24(26,27)28)32-22(33)8-3-15-12-30-20-6-1-13(9-17(20)23(15)32)14-2-7-21(29)31-11-14/h1-12H,(H2,29,31)
InChi Key MXRMEHBVJBSIPI-UHFFFAOYSA-N
Canonical SMILES C1=CC2=NC=C3C=CC(=O)N(C3=C2C=C1C4=CN=C(C=C4)N)C5=CC(=C(C=C5)F)C(F)(F)F
Isomeric SMILES C1=CC2=NC=C3C=CC(=O)N(C3=C2C=C1C4=CN=C(C=C4)N)C5=CC(=C(C=C5)F)C(F)(F)F
PubChem CID 51350805
Molecular Weight 450.39

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO

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Solution Calculators