QS11 - ≥98%, high purity , CAS No.944328-88-5

Item Number

Q274976

• Synonyms: MLS006010863 | QS11 | Q27166329 | BDBM50373058 | QS11 free | BDBM12590 | CS-6989 | (2S)-2-[[2-(2,3-dihydro-1H-inden-5-yloxy)-9-[(4-phenylphenyl)methyl]purin-6-yl]amino]-3-phenylpropan-1-ol | BRD-K02526760-001-01-5 | AKOS024457553 | Wnt Synergist, QS11 | (
• Specifications & Purity: ≥98%
• Biochemical and Physiological Mechanisms: Potent GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor (EC 50 = 0.5 μM). Wnt/β-catenin pathway modulator. Antitumor agent. Active in vitro .
• Storage Temp: Protected from light,Store at -20°C
• Shipped In: Ice chest + Ice pads
• Note: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Product Description

Product description

QS11 is an inhibitor of ARFGAP1 (ADP-ribosylation factor GTPase-activating protein 1), with an EC50 of 1.5 µM. QS11 modulates Wnt/β-catenin signaling through an effect on protein trafficking. QS11 inhibits migration of ARFGAP overexpressing breast cancer cells.