Determine the necessary mass, volume, or concentration for preparing a solution.
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Synonyms | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one | 2-[3,4-bis(oxidanyl)phenyl]-3-[(2S,3R,4S,5R,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5,7-bis(oxidanyl)chrom |
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Specifications & Purity | ≥97%(HPLC) |
Biochemical and Physiological Mechanisms | Protects against peroxide-induced oxidative damage to cells by scavenging reactive oxygen species and enhancing activity of anti-oxidant enzymes, in particular, catalase and glutathione peroxidase. |
Shipped In | Normal |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Pubchem Sid | 488195240 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488195240 |
IUPAC Name | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one |
INCHI | InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15+,17+,18-,21+/m1/s1 |
InChi Key | OVSQVDMCBVZWGM-DTGCRPNFSA-N |
Canonical SMILES | C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)OC4C(C(C(C(O4)CO)O)O)O)O)O |
Isomeric SMILES | C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O)O)O)O |
WGK Germany | 3 |
RTECS | DJ3009200 |
PubChem CID | 5281643 |
Molecular Weight | 464.38 |
Beilstein | 5784795 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
D2416465 | Certificate of Analysis | Apr 30, 2024 | Q123379 |
D2419433 | Certificate of Analysis | Apr 30, 2024 | Q123379 |
D2419434 | Certificate of Analysis | Apr 30, 2024 | Q123379 |
I2321914 | Certificate of Analysis | Sep 26, 2023 | Q123379 |
I2321963 | Certificate of Analysis | Sep 26, 2023 | Q123379 |
C23241325 | Certificate of Analysis | Apr 09, 2023 | Q123379 |
C23241388 | Certificate of Analysis | Apr 09, 2023 | Q123379 |
C23241389 | Certificate of Analysis | Apr 09, 2023 | Q123379 |
C23241554 | Certificate of Analysis | Apr 09, 2023 | Q123379 |
E1924159 | Certificate of Analysis | Mar 10, 2023 | Q123379 |
L2214273 | Certificate of Analysis | Dec 26, 2022 | Q123379 |
L2214282 | Certificate of Analysis | Dec 26, 2022 | Q123379 |
L2214286 | Certificate of Analysis | Dec 26, 2022 | Q123379 |
H1427045 | Certificate of Analysis | Jun 20, 2022 | Q123379 |
Pictogram(s) | GHS07 |
---|---|
Signal | Warning |
Hazard Statements | H302:Harmful if swallowed |
Precautionary Statements | P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
WGK Germany | 3 |
RTECS | DJ3009200 |
1. Liu Xinru, Ma Qianwei, Sun Yongjun, Ju Wenming, Kumrungsee Thanutchaporn, Zhou Zhongkai, Wang Lijuan, Cao Ruge. (2023) Effects of Processings and Complexation on Solubility, Antioxidant and Antibacterial Properties of Buckwheat Polyphenols. Food and Bioprocess Technology, (8): (1-13). [PMID:18063578] [10.1007/s11947-023-03217-8] |
2. Linzi Li, Xueying Lei, Lin Chen, Ya Ma, Jun Luo, Xuebo Liu, Xinglian Xu, Guanghong Zhou, Xianchao Feng. (2024) Protective mechanism of quercetin compounds against acrylamide-induced hepatotoxicity. Food Science and Human Wellness, 13 (225). [PMID:] [10.26599/FSHW.2022.9250019] |
3. Huiqun Fan, Mingshun Chen, Taotao Dai, Lizhen Deng, Chengmei Liu, Wei Zhou, Jun Chen. (2023) Phenolic compounds profile of Amomum tsaoko Crevost et Lemaire and their antioxidant and hypoglycemic potential. Food Bioscience, 52 (102508). [PMID:] [10.1016/j.fbio.2023.102508] |
4. Zhixin Xiao, Min Liu, Wentao Bi, David Da Yong Chen. (2023) Ionic liquid as hydrogen bond acceptor in the extraction of nutritional natural products. FOOD CHEMISTRY, 412 (135589). [PMID:36736187] [10.1016/j.foodchem.2023.135589] |
5. Zhixu Chen, Jincai Wang, Jiaming Yuan, Zhen Wang, Zhengchao Tu, Jacques Crommen, Wenhui Luo, Jialiang Guo, Tingting Zhang, Zhengjin Jiang. (2023) Rapid screening of neuraminidase inhibitors using an at-line nanofractionation platform involving parallel oseltamivir-sensitive/resistant neuraminidase bioassays. JOURNAL OF CHROMATOGRAPHY A, 1687 (463693). [PMID:36516530] [10.1016/j.chroma.2022.463693] |
6. Qi Dong, Na Hu, Huilan Yue, Honglun Wang, Yue Wei. (2022) Rapid screening of α-glucosidase inhibitors in Hypericum perforatum L. using bio-affinity chromatography coupled with UPLC/MS. BIOMEDICAL CHROMATOGRAPHY, 37 (2): (e5536). [PMID:36264709] [10.1002/bmc.5536] |
7. Yuan Pan, Hui-Wen Gu, Yi Lv, Xiao-Li Yin, Ying Chen, Wanjun Long, Haiyan Fu, Yuanbin She. (2022) Untargeted metabolomic analysis of Chinese red wines for geographical origin traceability by UPLC-QTOF-MS coupled with chemometrics. FOOD CHEMISTRY, 394 (133473). [PMID:35716498] [10.1016/j.foodchem.2022.133473] |
8. Liangmei Rao, Yifu Zhu, Zhongshu Duan, Ting Xue, Xuemin Duan, Yangping Wen, Annamalai Senthil Kumar, Weiming Zhang, Jingkun Xu, Akbar Hojjati-Najafabadi. (2022) Lotus seedpods biochar decorated molybdenum disulfide for portable, flexible, outdoor and inexpensive sensing of hyperin. CHEMOSPHERE, 301 (134595). [PMID:35427664] [10.1016/j.chemosphere.2022.134595] |
9. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin. Food & Function, 13 (9): (5061-5074). [PMID:35404372] [10.1039/D1FO03816H] |
10. Liuying Zhu, Wenting Li, Zeyuan Deng, Hongyan Li, Bing Zhang. (2020) The Composition and Antioxidant Activity of Bound Phenolics in Three Legumes, and Their Metabolism and Bioaccessibility of Gastrointestinal Tract. Foods, 9 (12): (1816). [PMID:33297502] [10.3390/foods9121816] |
11. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song. (2020) Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 239 (118519). [PMID:32480277] [10.1016/j.saa.2020.118519] |
12. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang. (2020) Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations. FOOD CHEMISTRY, 323 (126807). [PMID:32330646] [10.1016/j.foodchem.2020.126807] |
13. Guo Xiao, Zhang Yongtao, Lu Changhong, Qu Fengxia, Jiang Xianyan. (2020) Protective effect of hyperoside on heart failure rats via attenuating myocardial apoptosis and inducing autophagy. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 84 (4): (714-724). [PMID:31797747] [10.1080/09168451.2019.1685369] |
14. Yuhuan Chen, Qiwen Chen, Xiaozhong Wang, Fan Sun, Yawei Fan, Xiaoru Liu, Hongyan Li, Zeyuan Deng. (2020) Hemostatic action of lotus leaf charcoal is probably due to transformation of flavonol aglycons from flavonol glycosides in traditional Chinses medicine. JOURNAL OF ETHNOPHARMACOLOGY, 249 (112364). [PMID:31678413] [10.1016/j.jep.2019.112364] |
15. Na Wang, Jianyao Kou, Lijie Wang, Fei Wang, Kui Lu. (2019) Sensitive Electrochemical Determination of Hyperin Based on Electrochemically Activated ZrO2 Nanoparticles-Modified Carbon Paste Electrode. NANO, [PMID:] [10.1142/S1793292019500528] |
16. Li Wei, He Weiming, Xia Ping, Sun Wei, Shi Ming, Zhou Yao, Zhu Weiwei, Zhang Lu, Liu Buhui, Zhu Jingjing, Zhu Yiye, Zhou Enchao, Sun Minjie, Gao Kun. (2019) Total Extracts of Abelmoschus manihot L. Attenuates Adriamycin-Induced Renal Tubule Injury via Suppression of ROS-ERK1/2-Mediated NLRP3 Inflammasome Activation. Frontiers in Pharmacology, 10 [PMID:31191310] [10.3389/fphar.2019.00567] |
17. Nan Yang, Ruixia Qiu, Shuo Yang, Kangning Zhou, Chengtao Wang, Shiyi Ou, Jie Zheng. (2019) Influences of stir-frying and baking on flavonoid profile, antioxidant property, and hydroxymethylfurfural formation during preparation of blueberry-filled pastries. FOOD CHEMISTRY, 287 (167). [PMID:30857686] [10.1016/j.foodchem.2019.02.053] |
18. Yurong Ma, Qingfeng Ban, Jingying Shi, Tiantian Dong, Cai-Zhong Jiang, Qingguo Wang. (2019) 1-Methylcyclopropene (1-MCP), storage time, and shelf life and temperature affect phenolic compounds and antioxidant activity of ‘Jonagold’ apple. POSTHARVEST BIOLOGY AND TECHNOLOGY, 150 (71). [PMID:] [10.1016/j.postharvbio.2018.12.015] |
19. Danjing Wan, Yu Han, Farui Li, Hua Mao, Gang Chen. (2018) Far infrared-assisted removal of extraction solvent for capillary electrophoretic determination of the bioactive constituents in Plumula Nelumbinis. ELECTROPHORESIS, 40 (4): (582-586). [PMID:30488648] [10.1002/elps.201800477] |
20. Yu-Mei Zhao, Lv-Huan Wang, Si-Fan Luo, Qi-Qin Wang, Ruin Moaddel, Ting-Ting Zhang, Zheng-Jin Jiang. (2018) Magnetic beads-based neuraminidase enzyme microreactor as a drug discovery tool for screening inhibitors from compound libraries and fishing ligands from natural products. JOURNAL OF CHROMATOGRAPHY A, 1568 (123). [PMID:30005943] [10.1016/j.chroma.2018.07.031] |
21. Yang Huang, Ying Feng, Guangyun Tang, Minyi Li, Tingting Zhang, Marianne Fillet, Jacques Crommen, Zhengjin Jiang. (2017) Development and validation of a fast SFC method for the analysis of flavonoids in plant extracts. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 140 (384). [PMID:28347593] [10.1016/j.jpba.2017.03.012] |
22. Han Peng, Wenting Li, Hongyan Li, Zeyuan Deng, Bing Zhang. (2017) Extractable and non-extractable bound phenolic compositions and their antioxidant properties in seed coat and cotyledon of black soybean (Glycinemax (L.) merr). Journal of Functional Foods, 32 (296). [PMID:] [10.1016/j.jff.2017.03.003] |
23. Tong Wang, Hai-Long Wu, Li-Xia Xie, Li Zhu, Zhi Liu, Xiao-Dong Sun, Rong Xiao, Ru-Qin Yu. (2017) Fast and simultaneous determination of 12 polyphenols in apple peel and pulp by using chemometrics-assisted high-performance liquid chromatography with diode array detection. JOURNAL OF SEPARATION SCIENCE, 40 (8): (1651-1659). [PMID:28217915] [10.1002/jssc.201601293] |
24. Shuzhen Yang, Jie Zhou, Dongmei Li, Chunyu Shang, Litao Peng, Siyi Pan. (2017) The structure-antifungal activity relationship of 5,7-dihydroxyflavonoids against Penicillium italicum. FOOD CHEMISTRY, 224 (26). [PMID:28159264] [10.1016/j.foodchem.2016.12.001] |
25. Bai Yin, Zhou Wen-Di, Mu Xian-Min, Zhang Qian, Yu Chen, Di Bin, Su Meng-Xiang. (2017) Covalent Immobilization of Human Placental 17β-Hydroxysteroid Dehydrogenase Type 1 onto Glutaraldehyde Activated Silica Coupled with LC-TOF/MS for Anti-Cancer Drug Screening Applications. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 182 (2): (482-494). [PMID:27933483] [10.1007/s12010-016-2339-6] |
26. Huichao Li, Kai Sheng, Zhengkun Xie, Lina Zou, Baoxian Ye. (2016) Highly sensitive determination of hyperin on poly(diallyldimethylammonium chloride)-functionalized graphene modified electrode. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 776 (105). [PMID:] [10.1016/j.jelechem.2016.06.044] |
27. Hui Cao,Xiaojuan Liu,Nataša Poklar Ulrih,Pradeep K Sengupta,Jianbo Xiao. (2018-09-04) Plasma protein binding of dietary polyphenols to human serum albumin: A high performance affinity chromatography approach.. Food chemistry, 270 (257-263). [PMID:30174044] |
1. Liu Xinru, Ma Qianwei, Sun Yongjun, Ju Wenming, Kumrungsee Thanutchaporn, Zhou Zhongkai, Wang Lijuan, Cao Ruge. (2023) Effects of Processings and Complexation on Solubility, Antioxidant and Antibacterial Properties of Buckwheat Polyphenols. Food and Bioprocess Technology, (8): (1-13). [PMID:18063578] [10.1007/s11947-023-03217-8] |
2. Linzi Li, Xueying Lei, Lin Chen, Ya Ma, Jun Luo, Xuebo Liu, Xinglian Xu, Guanghong Zhou, Xianchao Feng. (2024) Protective mechanism of quercetin compounds against acrylamide-induced hepatotoxicity. Food Science and Human Wellness, 13 (225). [PMID:] [10.26599/FSHW.2022.9250019] |
3. Huiqun Fan, Mingshun Chen, Taotao Dai, Lizhen Deng, Chengmei Liu, Wei Zhou, Jun Chen. (2023) Phenolic compounds profile of Amomum tsaoko Crevost et Lemaire and their antioxidant and hypoglycemic potential. Food Bioscience, 52 (102508). [PMID:] [10.1016/j.fbio.2023.102508] |
4. Zhixin Xiao, Min Liu, Wentao Bi, David Da Yong Chen. (2023) Ionic liquid as hydrogen bond acceptor in the extraction of nutritional natural products. FOOD CHEMISTRY, 412 (135589). [PMID:36736187] [10.1016/j.foodchem.2023.135589] |
5. Zhixu Chen, Jincai Wang, Jiaming Yuan, Zhen Wang, Zhengchao Tu, Jacques Crommen, Wenhui Luo, Jialiang Guo, Tingting Zhang, Zhengjin Jiang. (2023) Rapid screening of neuraminidase inhibitors using an at-line nanofractionation platform involving parallel oseltamivir-sensitive/resistant neuraminidase bioassays. JOURNAL OF CHROMATOGRAPHY A, 1687 (463693). [PMID:36516530] [10.1016/j.chroma.2022.463693] |
6. Qi Dong, Na Hu, Huilan Yue, Honglun Wang, Yue Wei. (2022) Rapid screening of α-glucosidase inhibitors in Hypericum perforatum L. using bio-affinity chromatography coupled with UPLC/MS. BIOMEDICAL CHROMATOGRAPHY, 37 (2): (e5536). [PMID:36264709] [10.1002/bmc.5536] |
7. Yuan Pan, Hui-Wen Gu, Yi Lv, Xiao-Li Yin, Ying Chen, Wanjun Long, Haiyan Fu, Yuanbin She. (2022) Untargeted metabolomic analysis of Chinese red wines for geographical origin traceability by UPLC-QTOF-MS coupled with chemometrics. FOOD CHEMISTRY, 394 (133473). [PMID:35716498] [10.1016/j.foodchem.2022.133473] |
8. Liangmei Rao, Yifu Zhu, Zhongshu Duan, Ting Xue, Xuemin Duan, Yangping Wen, Annamalai Senthil Kumar, Weiming Zhang, Jingkun Xu, Akbar Hojjati-Najafabadi. (2022) Lotus seedpods biochar decorated molybdenum disulfide for portable, flexible, outdoor and inexpensive sensing of hyperin. CHEMOSPHERE, 301 (134595). [PMID:35427664] [10.1016/j.chemosphere.2022.134595] |
9. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin. Food & Function, 13 (9): (5061-5074). [PMID:35404372] [10.1039/D1FO03816H] |
10. Liuying Zhu, Wenting Li, Zeyuan Deng, Hongyan Li, Bing Zhang. (2020) The Composition and Antioxidant Activity of Bound Phenolics in Three Legumes, and Their Metabolism and Bioaccessibility of Gastrointestinal Tract. Foods, 9 (12): (1816). [PMID:33297502] [10.3390/foods9121816] |
11. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song. (2020) Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 239 (118519). [PMID:32480277] [10.1016/j.saa.2020.118519] |
12. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang. (2020) Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations. FOOD CHEMISTRY, 323 (126807). [PMID:32330646] [10.1016/j.foodchem.2020.126807] |
13. Guo Xiao, Zhang Yongtao, Lu Changhong, Qu Fengxia, Jiang Xianyan. (2020) Protective effect of hyperoside on heart failure rats via attenuating myocardial apoptosis and inducing autophagy. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 84 (4): (714-724). [PMID:31797747] [10.1080/09168451.2019.1685369] |
14. Yuhuan Chen, Qiwen Chen, Xiaozhong Wang, Fan Sun, Yawei Fan, Xiaoru Liu, Hongyan Li, Zeyuan Deng. (2020) Hemostatic action of lotus leaf charcoal is probably due to transformation of flavonol aglycons from flavonol glycosides in traditional Chinses medicine. JOURNAL OF ETHNOPHARMACOLOGY, 249 (112364). [PMID:31678413] [10.1016/j.jep.2019.112364] |
15. Na Wang, Jianyao Kou, Lijie Wang, Fei Wang, Kui Lu. (2019) Sensitive Electrochemical Determination of Hyperin Based on Electrochemically Activated ZrO2 Nanoparticles-Modified Carbon Paste Electrode. NANO, [PMID:] [10.1142/S1793292019500528] |
16. Li Wei, He Weiming, Xia Ping, Sun Wei, Shi Ming, Zhou Yao, Zhu Weiwei, Zhang Lu, Liu Buhui, Zhu Jingjing, Zhu Yiye, Zhou Enchao, Sun Minjie, Gao Kun. (2019) Total Extracts of Abelmoschus manihot L. Attenuates Adriamycin-Induced Renal Tubule Injury via Suppression of ROS-ERK1/2-Mediated NLRP3 Inflammasome Activation. Frontiers in Pharmacology, 10 [PMID:31191310] [10.3389/fphar.2019.00567] |
17. Nan Yang, Ruixia Qiu, Shuo Yang, Kangning Zhou, Chengtao Wang, Shiyi Ou, Jie Zheng. (2019) Influences of stir-frying and baking on flavonoid profile, antioxidant property, and hydroxymethylfurfural formation during preparation of blueberry-filled pastries. FOOD CHEMISTRY, 287 (167). [PMID:30857686] [10.1016/j.foodchem.2019.02.053] |
18. Yurong Ma, Qingfeng Ban, Jingying Shi, Tiantian Dong, Cai-Zhong Jiang, Qingguo Wang. (2019) 1-Methylcyclopropene (1-MCP), storage time, and shelf life and temperature affect phenolic compounds and antioxidant activity of ‘Jonagold’ apple. POSTHARVEST BIOLOGY AND TECHNOLOGY, 150 (71). [PMID:] [10.1016/j.postharvbio.2018.12.015] |
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