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Size

Availability

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Q104838-5g

In stock

$11.90

Q104838-10g

10g

In stock

$17.90

Q104838-25g

25g

In stock

$33.90

Q104838-50g

50g

In stock

$60.90

Q104838-100g

100g

In stock

$97.90

Q104838-250g

250g

In stock

$220.90

Q104838-500g

500g

Available within 4-8 weeks(?)

$418.90

Basic Description

Synonyms	BMK1-G2 \| Quercetin dihydrate \| Quercetin dihydrate - Sophoretin \| BCP07318 \| Quercetine dihydrate \| CCRIS 3304 \| Quercetin dihydrate (Sophoretin) \| HMS2096F15 \| QUERCETIN DIHYDRATE [WHO-DD] \| s2347 \| 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyr
Specifications & Purity	≥97%
Biochemical and Physiological Mechanisms	Quercetin dihydrate is a flavonoid with anticancer activity. Quercetin is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer
Storage Temp	Protected from light
Shipped In	Normal
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Quercetin is an antitrypanosomal and antileishmanial compound. Quercetin is a well-known bioflavonoid and its influence on tumour growth in vivo has been reported. Quercetic exhibits leishmanicidal effect on the amastigote stage of Leishmaniadonovani.

Associated Targets(Human)

CYP1A2 Tchem Cytochrome P450 1A2 (1 Activities)

Discover Target: CYP1A2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP2C9 Tchem Cytochrome P450 2C9 (1 Activities)

Discover Target: CYP2C9

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)

Discover Target: TSHR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX15B Tchem Arachidonate 15-lipoxygenase, type II (7244 Activities)

Discover Target: ALOX15B

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

Discover Target: CYP2D6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)

Discover Target: ALOX15

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

Discover Target: CYP1A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

Discover Target: CYP2C9

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)

Discover Target: CYP2C19

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TP53 Tchem Cellular tumor antigen p53 (48468 Activities)

Discover Target: TP53

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HEK293 (82097 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 Activities)

Discover Target: HIF1A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)

Discover Target: HSD17B10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLK Tbio DNA polymerase kappa (8653 Activities)

Discover Target: POLK

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

G6PD Tchem Glucose-6-phosphate 1-dehydrogenase (778 Activities)

Discover Target: G6PD

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)

Discover Target: KDM4E

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

USP2 Tbio Ubiquitin carboxyl-terminal hydrolase 2 (8818 Activities)

Discover Target: USP2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RECQL Tbio ATP-dependent DNA helicase Q1 (5575 Activities)

Discover Target: RECQL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)

Discover Target: USP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)

Discover Target: MEN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Cruzipain (33337 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Galc Galactocerebrosidase (11 Activities)

Discover Target: Galc

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Trypanosoma brucei brucei (13300 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

lef Anthrax lethal factor (7585 Activities)

Discover Target: lef

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Luciferin 4-monooxygenase (66902 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)

Discover Target: ffp

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488195287
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488195287
IUPAC Name	2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one;dihydrate
INCHI	InChI=1S/C15H10O7.2H2O/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6;;/h1-5,16-19,21H;2*1H2
InChi Key	GMGIWEZSKCNYSW-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O.O.O
Isomeric SMILES	C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O.O.O
WGK Germany	3
RTECS	LK8950000
Alternate CAS	849061-97-8
PubChem CID	5284452
UN Number	2811
Molecular Weight	338.27
Beilstein	317313

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

37 results found

Lot Number	Certificate Type	Date	Item
J2327639	Certificate of Analysis	Sep 28, 2023	Q104838
J2327642	Certificate of Analysis	Sep 20, 2023	Q104838
J2327640	Certificate of Analysis	Sep 20, 2023	Q104838
G2419020	Certificate of Analysis	Sep 20, 2023	Q104838
G2405077	Certificate of Analysis	Sep 20, 2023	Q104838
D2422073	Certificate of Analysis	Sep 20, 2023	Q104838
D2418084	Certificate of Analysis	Sep 20, 2023	Q104838
J2327641	Certificate of Analysis	Sep 20, 2023	Q104838
H2331041	Certificate of Analysis	Jul 04, 2023	Q104838
H2316039	Certificate of Analysis	Jul 04, 2023	Q104838
G2321923	Certificate of Analysis	Jul 04, 2023	Q104838
G2321902	Certificate of Analysis	Jul 04, 2023	Q104838
G2321901	Certificate of Analysis	Jul 04, 2023	Q104838
G2321889	Certificate of Analysis	Jul 04, 2023	Q104838
G2321888	Certificate of Analysis	Jul 04, 2023	Q104838
G2321879	Certificate of Analysis	Jul 04, 2023	Q104838
G2321880	Certificate of Analysis	Jul 04, 2023	Q104838
G2321884	Certificate of Analysis	Jul 04, 2023	Q104838
F2328839	Certificate of Analysis	Jun 12, 2023	Q104838
H1506032	Certificate of Analysis	Apr 11, 2023	Q104838
C2316363	Certificate of Analysis	Mar 04, 2023	Q104838
C2306368	Certificate of Analysis	Mar 04, 2023	Q104838
C2306369	Certificate of Analysis	Mar 04, 2023	Q104838
C2316330	Certificate of Analysis	Mar 04, 2023	Q104838
C2316343	Certificate of Analysis	Mar 04, 2023	Q104838
C2316374	Certificate of Analysis	Mar 04, 2023	Q104838
C2316373	Certificate of Analysis	Mar 04, 2023	Q104838
C2316372	Certificate of Analysis	Mar 04, 2023	Q104838
C2316371	Certificate of Analysis	Mar 04, 2023	Q104838
C2316370	Certificate of Analysis	Mar 04, 2023	Q104838
C2316364	Certificate of Analysis	Mar 04, 2023	Q104838
C2316344	Certificate of Analysis	Mar 04, 2023	Q104838
B2318464	Certificate of Analysis	Jun 08, 2022	Q104838
F2205294	Certificate of Analysis	Jun 08, 2022	Q104838
F2205297	Certificate of Analysis	Apr 06, 2022	Q104838
C2225055	Certificate of Analysis	Apr 06, 2022	Q104838
C2225054	Certificate of Analysis	Apr 06, 2022	Q104838

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Chemical and Physical Properties

Solubility	Soluble in DMSO (68 mg/ml at 25°C), Acetic Acid (1 mg/ml), Aqueous Alkali (1 mg/ml), water (<1 at 25°C), and ethanol (21 mg/ml at 25°C).
Sensitivity	Light sensitive.
Melt Point(°C)	>300°C

Safety and Hazards(GHS)

Pictogram(s)	GHS06
Signal	Danger
Hazard Statements	H301:Toxic if swallowed
Precautionary Statements	P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P316:IF SWALLOWED: Get emergency medical help immediately.
WGK Germany	3
RTECS	LK8950000

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Siyu Gui, Weiwei Tang, Zhihao Huang, Xinchen Wang, Siyin Gui, Xiang Gao, Duncheng Xiao, Liming Tao, Zhengxuan Jiang, Xianwen Wang. (2023) Ultrasmall Coordination Polymer Nanodots Fe-Quer Nanozymes for Preventing and Delaying the Development and Progression of Diabetic Retinopathy. ADVANCED FUNCTIONAL MATERIALS, (2300261). [PMID:] [10.1002/adfm.202300261]
2. Do Hee Kim, Eun Woo Jeong, Youjin Baek, Hyeon Gyu Lee. (2023) Development of propolis extract-loaded nanoparticles with chitosan and hyaluronic acid for improving solubility and stability. LWT-FOOD SCIENCE AND TECHNOLOGY, 181 (114738). [PMID:] [10.1016/j.lwt.2023.114738]
3. Jinhao Zhao, Minmin Liang, Zhongyan Wang, Yanyan Zhao, Jingli Cheng, Yongjun Du. (2022) Evaluation and optimization of blends for attracting Trichogramma dendrolimi based on semiochemicals mediating tritrophic interactions in the orchard habitat. BIOLOGICAL CONTROL, 173 (104998). [PMID:] [10.1016/j.biocontrol.2022.104998]
4. Jian-Feng Zhou, Wen-Jun Wang, Zhong-Ping Yin, Guo-Dong Zheng, Ji-Guang Chen, Jing-En Li, Ling-Li Chen, Qing-Feng Zhang. (2021) Quercetin is a promising pancreatic lipase inhibitor in reducing fat absorption in vivo. Food Bioscience, 43 (101248). [PMID:] [10.1016/j.fbio.2021.101248]
5. Chang Ping Yang, Li He, Cheng Zhi Huang, Yuan Fang Li, Shu Jun Zhen. (2021) Continuous singlet oxygen generation for persistent chemiluminescence in Cu-MOFs-based catalytic system. TALANTA, 221 (121498). [PMID:33076101] [10.1016/j.talanta.2020.121498]
6. Xu Lujing, Shu Tong, Liu Songbai. (2019) Simplified Quantification of Representative Bioactives in Food Through TLC Image Analysis. Food Analytical Methods, 12 (12): (2886-2894). [PMID:] [10.1007/s12161-019-01645-x]

References

1. Ishida K et al.. (2017) Inhibition of PI3K suppresses propagation of drug-tolerant cancer cell subpopulations enriched by 5-fluorouracil.. Sci Rep, 7 (2262). [PMID:28536445]
2. Lin YJ et al.. (2019) Network analysis and mechanisms of action of Chinese herb-related natural compounds in lung cancer cells.. Phytomedicine, 58 (152893). [PMID:30901663]
3. Siyu Gui, Weiwei Tang, Zhihao Huang, Xinchen Wang, Siyin Gui, Xiang Gao, Duncheng Xiao, Liming Tao, Zhengxuan Jiang, Xianwen Wang. (2023) Ultrasmall Coordination Polymer Nanodots Fe-Quer Nanozymes for Preventing and Delaying the Development and Progression of Diabetic Retinopathy. ADVANCED FUNCTIONAL MATERIALS, (2300261). [PMID:] [10.1002/adfm.202300261]
4. Do Hee Kim, Eun Woo Jeong, Youjin Baek, Hyeon Gyu Lee. (2023) Development of propolis extract-loaded nanoparticles with chitosan and hyaluronic acid for improving solubility and stability. LWT-FOOD SCIENCE AND TECHNOLOGY, 181 (114738). [PMID:] [10.1016/j.lwt.2023.114738]
5. Jinhao Zhao, Minmin Liang, Zhongyan Wang, Yanyan Zhao, Jingli Cheng, Yongjun Du. (2022) Evaluation and optimization of blends for attracting Trichogramma dendrolimi based on semiochemicals mediating tritrophic interactions in the orchard habitat. BIOLOGICAL CONTROL, 173 (104998). [PMID:] [10.1016/j.biocontrol.2022.104998]
6. Jian-Feng Zhou, Wen-Jun Wang, Zhong-Ping Yin, Guo-Dong Zheng, Ji-Guang Chen, Jing-En Li, Ling-Li Chen, Qing-Feng Zhang. (2021) Quercetin is a promising pancreatic lipase inhibitor in reducing fat absorption in vivo. Food Bioscience, 43 (101248). [PMID:] [10.1016/j.fbio.2021.101248]
7. Chang Ping Yang, Li He, Cheng Zhi Huang, Yuan Fang Li, Shu Jun Zhen. (2021) Continuous singlet oxygen generation for persistent chemiluminescence in Cu-MOFs-based catalytic system. TALANTA, 221 (121498). [PMID:33076101] [10.1016/j.talanta.2020.121498]
8. Xu Lujing, Shu Tong, Liu Songbai. (2019) Simplified Quantification of Representative Bioactives in Food Through TLC Image Analysis. Food Analytical Methods, 12 (12): (2886-2894). [PMID:] [10.1007/s12161-019-01645-x]

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Quercetin dihydrate - 97%, high purity , CAS No.6151-25-3

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Mechanisms of Action

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Show more⌵

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Citations of This Product

References

Solution Calculators

Molarity Calculator

Dilution Calculator

Reconstitution Calculator