Skip to the beginning of the images gallery

Quinidine Sulfate - 98%, high purity , Sodium channel alpha subunit blocker, CAS No.6591-63-5, Sodium channel alpha subunit blocker

≥98%

CAS#: 6591-63-5
Formula: C₄₀H₄₈N₄O₄.H₂SO₄.2H₂O
Molecular Weight: 782.94
Beilstein Registry Number: 23(2)415
EC Number: 200-046-3
MDL number: MFCD00149346
PubChem CID: 656862
PubChem SID: 488191000

Item Number

Q109529

Grouped product items
SKU	Size	Availability	Price
Q109529-1g	1g	In stock	$13.90
Q109529-5g	5g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$52.90
Q109529-25g	25g	In stock	$236.90
Q109529-100g	100g	In stock	$851.90

Basic Description

Synonyms	Quinidine sulfate dihydrate \| 6591-63-5 \| Quinidine sulfate \| Cin-Quin \| Quinidine sulfate hydrate \| Quinidex Extentabs \| quinidine sulphate dihydrate \| Quinidex \| Quinora \| Quinidine sulphate \| Quinidine, sulfate, hydrate (2:1:2) \| Quinidine sulfate salt dihydrate \| J13S2394HE \|
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Quinidine sulfate dihydrate is an antiarrhythmic agent and an effective K + channel blocker with an IC50 value of 19.9 μm. Quinidine sulfate dihydrate is an effective and selective cytochrome P450DB (cytochrome P450DB) inhibitor, which can also be used in
Storage Temp	Protected from light
Shipped In	Normal
Action Type	BLOCKER
Mechanism of action	Sodium channel alpha subunit blocker

Associated Targets(Human)

CYP2D6 Tclin Cytochrome P450 2D6 (2 Activities)

Discover Target: CYP2D6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

Discover Target: CYP2D6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

INPP5D Tbio Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 (17 Activities)

Discover Target: INPP5D

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

pol Human immunodeficiency virus type 1 reverse transcriptase (18245 Activities)

Discover Target: pol

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Plasmodium falciparum (966862 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cavia porcellus (23802 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rattus norvegicus (775804 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Inppl1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 (2 Activities)

Discover Target: Inppl1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

Pubchem Sid	488191000
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488191000
IUPAC Name	(S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;sulfuric acid;dihydrate
INCHI	InChI=1S/2C20H24N2O2.H2O4S.2H2O/c21-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h23-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);21H2/t213-,14-,19+,20-;;;/m00.../s1
InChi Key	ZHNFLHYOFXQIOW-AHSOWCEXSA-N
Canonical SMILES	COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O.COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O.O.O.OS(=O)(=O)O
Isomeric SMILES	COC1=CC2=C(C=CN=C2C=C1)[C@@H]([C@H]3C[C@@H]4CCN3C[C@@H]4C=C)O.COC1=CC2=C(C=CN=C2C=C1)[C@@H]([C@H]3C[C@@H]4CCN3C[C@@H]4C=C)O.O.O.OS(=O)(=O)O
WGK Germany	3
RTECS	VA5605000
PubChem CID	656862
Molecular Weight	782.94
Beilstein	23(2)415

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

4 results found

Lot Number	Certificate Type	Date	Item
J2219385	Certificate of Analysis	Aug 04, 2022	Q109529
J2219387	Certificate of Analysis	Aug 04, 2022	Q109529
J2219690	Certificate of Analysis	Aug 04, 2022	Q109529
J2219783	Certificate of Analysis	Aug 04, 2022	Q109529

Solubility

Soluble in chloroform, water (11 mg/ml at 20°C), alcohol, and ethanol (50 mg/ml).

Sensitivity

Light sensitive.

Melt Point(°C)

212-214°C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H302:Harmful if swallowed
Precautionary Statements	P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help.
WGK Germany	3
RTECS	VA5605000

Solution Calculators

Molarity Calculator

Determine the necessary mass, volume, or concentration for preparing a solution.

Dilution Calculator

Determine the dilution needed to prepare a stock solution.