Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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Q105030-1g | 1g | In stock | $31.90 | |
Q105030-5g | 5g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $99.90 | |
Q105030-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $343.90 | |
Q105030-100g | 100g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $961.90 |
Synonyms | (9R)-6'-methoxy-8alpha-cinchonan-9-ol | Quinoline alkaloid | Quinsan | (R)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol | GNF-Pf-506 | HMS2089E05 | (R)-(-)-Quinine, 6-methoxycinchonidine | DB00468 | EINECS 205-00 |
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Specifications & Purity | Moligand™, for fluorescence analysis, ≥98% |
Biochemical and Physiological Mechanisms | Potassium channel blocker |
Storage Temp | Protected from light,Argon charged |
Shipped In | Normal |
Grade | for fluorescence analysis, Moligand™ |
Action Type | AGONIST, CHANNEL BLOCKER, INHIBITOR |
Mechanism of action | Agonist of TAS2R14;Agonist of TAS2R40;Channel blocker of K 2P18.1;Channel blocker of K v2.2;Inhibitor of Plasma membrane monoamine transporter |
Product Description | Quinine is a primary alkaloid of various species of Cinchona, optical isomer of Quinidine and an anti-malarial, skeletal, muscle relaxant. |
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IUPAC Name | (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol |
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INCHI | InChI=1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1 |
InChi Key | LOUPRKONTZGTKE-WZBLMQSHSA-N |
Canonical SMILES | COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O |
Isomeric SMILES | COC1=CC2=C(C=CN=C2C=C1)[C@H]([C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)O |
WGK Germany | 3 |
RTECS | VA6020000 |
PubChem CID | 3034034 |
Molecular Weight | 324.42 |
Beilstein | 91867 |
Reaxy-Rn | 5293630 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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H2103381 | Certificate of Analysis | May 17, 2024 | Q105030 |
H2103380 | Certificate of Analysis | May 13, 2024 | Q105030 |
H2103382 | Certificate of Analysis | May 13, 2024 | Q105030 |
H2103383 | Certificate of Analysis | May 13, 2024 | Q105030 |
C2422084 | Certificate of Analysis | Jun 01, 2022 | Q105030 |
H2206218 | Certificate of Analysis | Jun 01, 2022 | Q105030 |
H2206248 | Certificate of Analysis | Jun 01, 2022 | Q105030 |
H2206272 | Certificate of Analysis | Jun 01, 2022 | Q105030 |
Solubility | Soluble in alcohol, chloroform and diethyl ether. Slightly soluble in water and glycerol. |
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Sensitivity | Light & Moisture Sensitive. |
Melt Point(°C) | 173-177°C |
Pictogram(s) | GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H302:Harmful if swallowed H317:May cause an allergic skin reaction H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P284:[In case of inadequate ventilation] Wear respiratory protection. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately. |
WGK Germany | 3 |
RTECS | VA6020000 |
Reaxy-Rn | 5293630 |
Merck Index | 8061 |
1. Qing Li, Yu-Meng Guo, Xiang-Yi He, Guang-Li Li. (2023) Bifunctional Cu(II)-containing PDA-PEI copolymer dots: Demonstration of a dual-mode platform for colorimetric-fluorescent detection of glyphosate in the environment. TALANTA, 265 (124865). [PMID:37418960] |
2. Qing Wang,Jing Li,Xin Yang,Li Xu,Zhi-guo Shi,Lan-Ying Xu. (2014-08-17) Investigation on performance of zirconia and magnesia-zirconia stationary phases in hydrophilic interaction chromatography.. Talanta, 129 (438-447). [PMID:25127617] |
3. Liyun Ma,Simin Liu,Qing Wang,Lin Yao,Li Xu. (2015-02-03) Cucurbit(6)uril immobilized on silica: a novel high-performance liquid chromatographic stationary phase.. Journal of separation science, 38 ((7)): (1082-1089). [PMID:25641573] |
1. Achan J, Talisuna AO, Erhart A, Yeka A, Tibenderana JK, Baliraine FN, Rosenthal PJ, D'Alessandro U. (2011) Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria.. Malar J, 10 (3): (144). [PMID:21609473] |
2. Qing Li, Yu-Meng Guo, Xiang-Yi He, Guang-Li Li. (2023) Bifunctional Cu(II)-containing PDA-PEI copolymer dots: Demonstration of a dual-mode platform for colorimetric-fluorescent detection of glyphosate in the environment. TALANTA, 265 (124865). [PMID:37418960] |
3. Qing Wang,Jing Li,Xin Yang,Li Xu,Zhi-guo Shi,Lan-Ying Xu. (2014-08-17) Investigation on performance of zirconia and magnesia-zirconia stationary phases in hydrophilic interaction chromatography.. Talanta, 129 (438-447). [PMID:25127617] |
4. Liyun Ma,Simin Liu,Qing Wang,Lin Yao,Li Xu. (2015-02-03) Cucurbit(6)uril immobilized on silica: a novel high-performance liquid chromatographic stationary phase.. Journal of separation science, 38 ((7)): (1082-1089). [PMID:25641573] |