Basic Description

Synonyms	SCHEMBL124520 \| AKOS027327559 \| Ext D and C Red No. 15 \| Pharmakon1600-01503420 \| 2-(1-Piperazinyl)quinoline (Z)-2-butenedioate (1:1) \| CAS-5786-68-5 \| MFCD00133796 \| Quipazine maleate salt \| 2-[1-PIPERAZINYL]QUINOLINE MALEATE SALT \| NSC 758469 \| Tox21_11
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Quipazine dimaleate is a selective agonist of 5-HT3 receptors (SR-3, HTR3). 5-HT3 receptors (SR-3, HTR3) are neuronal ligand-gated ion channels that produce excitatory responses in neurons when activated by seratonin or other agonists for the receptor. Qu
Shipped In	Normal
Product Description	A selective 5-HT3 receptor agonist

Associated Targets(Human)

GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HSD17B10 Tchem Endoplasmic reticulum-associated amyloid beta-peptide-binding protein (20669 Activities)

Discover Target: HSD17B10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

Discover Target: TDP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)

Discover Target: KDM4E

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)

Discover Target: SLCO1B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)

Discover Target: SLCO1B3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	(Z)-but-2-enedioic acid;2-piperazin-1-ylquinoline
INCHI	InChI=1S/C13H15N3.C4H4O4/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16;5-3(6)1-2-4(7)8/h1-6,14H,7-10H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChi Key	QYJJDHZHSCTBII-BTJKTKAUSA-N
Canonical SMILES	C1CN(CCN1)C2=NC3=CC=CC=C3C=C2.C(=CC(=O)O)C(=O)O
Isomeric SMILES	C1CN(CCN1)C2=NC3=CC=CC=C3C=C2.C(=C\C(=O)O)\C(=O)O
WGK Germany	3
RTECS	VC2515000
PubChem CID	5702242
Molecular Weight	329.35

Certificates

Certificate of Analysis(COA)

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1 results found

Lot Number	Certificate Type	Date	Item
E1719029	Certificate of Analysis	Nov 11, 2022	Q137284

Safety and Hazards(GHS)

Pictogram(s)	GHS05, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H335:May cause respiratory irritation H318:Causes serious eye damage
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection.
WGK Germany	3
RTECS	VC2515000

FAQs and Articles

FAQ

Cytokines and Inflammation

Categories: Technical articles

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Cytokines Inflammation

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SKU	Size	Availability	Price
Q137284-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$36.90
Q137284-100mg	100mg	In stock	$113.90
Q137284-500mg	500mg	In stock	$508.90

Quipazine maleate salt - ≥98%, high purity , CAS No.5786-68-5